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PDB: 51586 results

5VK1
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BU of 5vk1 by Molmil
Crystal structure of human MDM4 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
Descriptor: Lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI, Protein Mdm4
Authors:Tolbert, W.D, Gohain, N, Pazgier, M.
Deposit date:2017-04-20
Release date:2018-04-25
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
Chem Sci, 10, 2019
1VPD
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BU of 1vpd by Molmil
X-Ray Crystal Structure of Tartronate Semialdehyde Reductase [Salmonella Typhimurium LT2]
Descriptor: CHLORIDE ION, L(+)-TARTARIC ACID, TARTRONATE SEMIALDEHYDE REDUCTASE
Authors:Osipiuk, J, Zhou, M, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2004-10-22
Release date:2004-10-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:X-ray crystal structure of GarR-tartronate semialdehyde reductase from Salmonella typhimurium.
J Struct Funct Genomics, 10, 2009
5VK0
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BU of 5vk0 by Molmil
Crystal structure of human MDM2 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, Lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
Authors:Tolbert, W.D, Gohain, N, Pazgier, M.
Deposit date:2017-04-20
Release date:2018-04-25
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
Chem Sci, 10, 2019
7CIF
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BU of 7cif by Molmil
Crystal structure of L-methionine decarboxylase from Streptomyces sp.590 (internal aldimine form).
Descriptor: L-methionine decarboxylase
Authors:Okawa, A, Shiba, T, Hayashi, M, Onoue, Y, Murota, M, Sato, D, Inagaki, J, Tamura, T, Harada, S, Inagaki, K.
Deposit date:2020-07-07
Release date:2021-01-27
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for substrate specificity of l-methionine decarboxylase.
Protein Sci., 30, 2021
1VYN
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BU of 1vyn by Molmil
STRUCTURE AND NUCLEIC ACID BINDING OF THE DROSOPHILA ARGONAUTE2 PAZ DOMAIN
Descriptor: ARGONAUTE2
Authors:Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
Deposit date:2004-05-03
Release date:2004-05-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain.
Nature, 426, 2003
5VLD
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BU of 5vld by Molmil
Crystal Structure of Medicago truncatula L-Histidinol Dehydrogenase in Complex with L-Histidine and NAD+
Descriptor: DI(HYDROXYETHYL)ETHER, HISTIDINE, Histidinol dehydrogenase, ...
Authors:Ruszkowski, M, Dauter, Z.
Deposit date:2017-04-25
Release date:2017-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structures of Medicago truncatula L-Histidinol Dehydrogenase Show Rearrangements Required for NAD(+) Binding and the Cofactor Positioned to Accept a Hydride.
Sci Rep, 7, 2017
5VRK
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BU of 5vrk by Molmil
Crystal structure of SsoPox AsA6 mutant (F46L-C258A-W263M-I280T) - open form
Descriptor: 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ...
Authors:Hiblot, J, Gotthard, G, Jacquet, P, Daude, D, Bergonzi, C, Chabriere, E, Elias, M.
Deposit date:2017-05-10
Release date:2018-01-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase.
Sci Rep, 7, 2017
1W3A
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BU of 1w3a by Molmil
Three dimensional structure of a novel pore-forming lectin from the mushroom Laetiporus sulphureus
Descriptor: GLYCEROL, HEMOLYTIC LECTIN LSLA, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose
Authors:Mancheno, J.M, Tateno, H, Goldstein, I.J, Martinez-Ripoll, M, Hermoso, J.A.
Deposit date:2004-07-14
Release date:2005-02-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Analysis of the Laetiporus Sulphureus Hemolytic Pore-Forming Lectin in Complex with Sugars
J.Biol.Chem., 280, 2005
1VT7
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BU of 1vt7 by Molmil
Structures of the mismatched duplex D(GGGTGCCC)
Descriptor: DNA (5'-D(*GP*GP*GP*TP*GP*CP*CP*C)-3')
Authors:Rabinovich, D, Haran, T, Eisenstein, M, Shakked, Z.
Deposit date:1996-12-02
Release date:2011-07-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of the mismatched duplex d(GGGTGCCC) and one of its Watson-Crick analogues d(GGGCGCCC).
J.Mol.Biol., 200, 1988
6QZR
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BU of 6qzr by Molmil
14-3-3 sigma in complex with FOXO1 pT24 peptide
Descriptor: 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Forkhead box protein O1, ...
Authors:Ottmann, C, Wolter, M, Lau, R.A.
Deposit date:2019-03-12
Release date:2019-07-31
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating interactions with 14-3-3 proteins.
J.Biol.Chem., 294, 2019
7MU4
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BU of 7mu4 by Molmil
Crystal Structure of HPV L1-directed D24.M01Fab
Descriptor: D24.M01 Fab Heavy Chain, D24.M01 Fab Light Chain, DI(HYDROXYETHYL)ETHER
Authors:Singh, S, Pancera, M.
Deposit date:2021-05-14
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural Characterisation of Immune Responses to HPV Vaccination
To Be Published
1VD7
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BU of 1vd7 by Molmil
Solution structure of FMBP-1 tandem repeat 1
Descriptor: Fibroin-modulator-binding-protein-1
Authors:Kawaguchi, K, Yamaki, T, Aizawa, T, Takiya, S, Demura, M, Nitta, K.
Deposit date:2004-03-20
Release date:2005-03-29
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of FMBP-1 tandem repeat 1
To be Published
4OWF
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BU of 4owf by Molmil
Crystal structure of the NEMO CoZi in complex with HOIP NZF1 domain
Descriptor: E3 ubiquitin-protein ligase RNF31, NF-kappa-B essential modulator, ZINC ION
Authors:Rahighi, S, Fujita, H, Kawasaki, M, Kato, R, Iwai, K, Wakatsuki, S.
Deposit date:2014-01-31
Release date:2014-02-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism Underlying I kappa B Kinase Activation Mediated by the Linear Ubiquitin Chain Assembly Complex.
Mol.Cell.Biol., 34, 2014
7C61
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BU of 7c61 by Molmil
Crystal structure of 5-HT1B-BRIL and SRP2070_Fab complex
Descriptor: 5-hydroxytryptamine receptor 1B,Soluble cytochrome b562,5-hydroxytryptamine receptor 1B, Ergotamine, IGG HEAVY CHAIN, ...
Authors:Suzuki, M, Miyagi, H, Asada, H, Yasunaga, M, Suno, C, Takahashi, Y, Saito, J, Iwata, S.
Deposit date:2020-05-21
Release date:2020-07-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:The discovery of a new antibody for BRIL-fused GPCR structure determination.
Sci Rep, 10, 2020
1VEG
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BU of 1veg by Molmil
Solution Structure of RSGI RUH-012, a UBA Domain from Mouse cDNA
Descriptor: NEDD8 ultimate buster-1
Authors:Abe, T, Hirota, H, Izumi, K, Yoshida, M, Yamazaki, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-03-31
Release date:2004-09-30
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of RSGI RUH-012, a UBA Domain from Mouse cDNA
To be Published
4UBD
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BU of 4ubd by Molmil
Crystal structure of a neutralizing human monoclonal antibody with 1968 H3 HA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Shore, D.A, Yang, H, Cho, M, Donis, R.O, Stevens, J.
Deposit date:2014-08-12
Release date:2015-06-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus.
Nat Commun, 6, 2015
7MWN
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BU of 7mwn by Molmil
An engineered PYL2-based WIN 55,212-2 synthetic cannabinoid sensor with a stabilized HAB1 variant
Descriptor: ACETATE ION, Abscisic acid receptor PYL2, CHLORIDE ION, ...
Authors:Peterson, F.C, Beltran, J, Bedewitz, M, Steiner, P.J, Cutler, S.R, Whitehead, T.A.
Deposit date:2021-05-17
Release date:2022-06-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Rapid biosensor development using plant hormone receptors as reprogrammable scaffolds.
Nat.Biotechnol., 40, 2022
7MNW
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BU of 7mnw by Molmil
Crystal Structure of Nup358/RanBP2 Ran-binding domain 1 in complex with Ran-GPPNHP
Descriptor: E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, MAGNESIUM ION, ...
Authors:Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
Deposit date:2021-05-01
Release date:2022-06-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
1VGO
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BU of 1vgo by Molmil
Crystal Structure of Archaerhodopsin-2
Descriptor: Archaerhodopsin 2, RETINAL, SULFATE ION, ...
Authors:Yoshimura, K, Enami, N, Murakami, M, Okumura, H, Ihara, K, Kouyama, T.
Deposit date:2004-04-28
Release date:2005-10-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of archaerhodopsin-1 and -2: Common structural motif in archaeal light-driven proton pumps
J.Mol.Biol., 358, 2006
7MNZ
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BU of 7mnz by Molmil
Crystal Structure of Nup358/RanBP2 Ran-binding domain 4 in complex with Ran-GPPNHP
Descriptor: E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, MAGNESIUM ION, ...
Authors:Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
Deposit date:2021-05-01
Release date:2022-06-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MO1
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BU of 7mo1 by Molmil
Crystal Structure of the ZnF1 of Nucleoporin NUP153 in complex with Ran-GDP
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
Deposit date:2021-05-01
Release date:2022-06-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
1VIP
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BU of 1vip by Molmil
ANTICOAGULANT CLASS II PHOSPHOLIPASE A2 FROM THE VENOM OF VIPERA RUSSELLI RUSSELLI
Descriptor: PHOSPHOLIPASE A2, SULFATE ION
Authors:Carredano, E, Westerlund, B, Persson, B, Saarinen, M, Ramaswamy, S, Eaker, D, Eklund, H.
Deposit date:1997-02-27
Release date:1997-06-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The three-dimensional structures of two toxins from snake venom throw light on the anticoagulant and neurotoxic sites of phospholipase A2.
Toxicon, 36, 1998
7MNP
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BU of 7mnp by Molmil
Crystal Structure of the ZnF2 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP
Descriptor: E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
Deposit date:2021-05-01
Release date:2022-06-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
6QMF
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BU of 6qmf by Molmil
Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis in complex with 5-[3-(1H-indol-3-yl)propoxy]-1-phenyl-1H-pyrazole-4-carboxylic acid at 1.8A resolution.
Descriptor: 3-indol-1-ylpropanoic acid, DIMETHYL SULFOXIDE, Phosphopantetheine adenylyltransferase
Authors:Blaszczyk, M, Blundell, T.L.
Deposit date:2019-02-07
Release date:2020-02-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.771 Å)
Cite:Fragment linking applied to the discovery of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase inhibitors
To Be Published
7MNJ
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BU of 7mnj by Molmil
Crystal structure of the N-terminal domain of NUP358/RanBP2 (residues 145-673)
Descriptor: E3 SUMO-protein ligase RanBP2
Authors:Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Patke, A, Dasso, M, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
Deposit date:2021-05-01
Release date:2022-06-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022

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