7QOY
 
 | | A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability | | 分子名称: | CHLORIDE ION, COBALT (III) ION, Nitrile hydratase, ... | | 著者 | Van Wyk, J.C, Cowan, D.A, Danson, M.J, Tsekoa, T.L, Sayed, M.F, Sewell, B.T. | | 登録日 | 2021-12-29 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability
To be published
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7QOP
 | | A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability | | 分子名称: | CHLORIDE ION, COBALT (II) ION, MAGNESIUM ION, ... | | 著者 | Van Wyk, J.C, Cowan, D.A, Danson, M.J, Tsekoa, T.L, Sayed, M.F, Sewell, B.T. | | 登録日 | 2021-12-24 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Engineering enhanced thermostability into the Geobacillus pallidus nitrile hydratase.
Curr Res Struct Biol, 4, 2022
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5NG5
 | | multi-drug efflux; membrane transport; RND superfamily; Drug resistance | | 分子名称: | 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrA, ... | | 著者 | Wang, Z, Fan, G, Hryc, C.F, Blaza, J.N, Serysheva, I.I, Schmid, M.F, Chiu, W, Luisi, B.F, Du, D. | | 登録日 | 2017-03-16 | | 公開日 | 2017-04-19 | | 最終更新日 | 2017-08-02 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump.
Elife, 6, 2017
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7QOM
 | | A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability | | 分子名称: | CHLORIDE ION, COBALT (II) ION, Nitrile hydratase, ... | | 著者 | Van Wyk, J.C, Cowan, D.A, Danson, M.J, Tsekoa, T.L, Sayed, M.F, Sewell, B.T. | | 登録日 | 2022-03-17 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability
To be published
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5NPR
 | | The human O-GlcNAc transferase in complex with a thiol-linked bisubstrate inhibitor | | 分子名称: | POTASSIUM ION, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, [[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] propyl hydrogen phosphate, ... | | 著者 | Rafie, K, van Aalten, D.M.F. | | 登録日 | 2017-04-18 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Thio-Linked UDP-Peptide Conjugates as O-GlcNAc Transferase Inhibitors.
Bioconjug. Chem., 29, 2018
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5O0K
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5KNI
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5KQ5
 | | AMPK bound to allosteric activator | | 分子名称: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... | | 著者 | Calabrese, M.F, Kurumbail, R.G. | | 登録日 | 2016-07-05 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | | 主引用文献 | Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy.
J.Med.Chem., 59, 2016
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5O0M
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5O0R
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5O0O
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5OAT
 | | PINK1 structure | | 分子名称: | MAGNESIUM ION, Serine/threonine-protein kinase PINK1, mitochondrial-like Protein | | 著者 | Kumar, A, Tamjar, J, Woodroof, H.I, Raimi, O.G, Waddell, A.Y, Peggie, M, Muqit, M.M.K, van Aalten, D.M.F. | | 登録日 | 2017-06-23 | | 公開日 | 2017-10-11 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | Structure of PINK1 and mechanisms of Parkinson's disease associated mutations.
Elife, 6, 2017
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7PIZ
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5L2H
 | | Crystal Structure of W26A mutant of anti-EGFR Centyrin P54AR4-83v2 | | 分子名称: | Centyrin, GLYCEROL | | 著者 | Cardoso, R.M.F, Goldberg, S.D, O Neil, K.T, Gilliland, G.L. | | 登録日 | 2016-08-01 | | 公開日 | 2016-11-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.8013 Å) | | 主引用文献 | Engineering a targeted delivery platform using Centyrins.
Protein Eng. Des. Sel., 29, 2016
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5O0L
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5O0P
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5LFR
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5LFV
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5LJ3
 | | Structure of the core of the yeast spliceosome immediately after branching | | 分子名称: | CEF1, CLF1, CWC15, ... | | 著者 | Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K. | | 登録日 | 2016-07-17 | | 公開日 | 2016-08-03 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structure of the spliceosome immediately after branching.
Nature, 537, 2016
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5O0N
 | | Deglycosylated Nogo Receptor with native disulfide structure 4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Reticulon-4 receptor, ... | | 著者 | Pronker, M.F, Tas, R.P, Vlieg, H.C, Janssen, B.J.C. | | 登録日 | 2017-05-16 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Nogo Receptor crystal structures with a native disulfide pattern suggest a novel mode of self-interaction.
Acta Crystallogr D Struct Biol, 73, 2017
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5O0Q
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7QE5
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5LF5
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7SGN
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7SGO
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