8ZWF
 
 | cryoEM structure of JR14a bound C3aR-BRIL-BAG2 complex | Descriptor: | (2~{S})-5-[bis(azanyl)methylideneamino]-2-[[5-[bis(4-chlorophenyl)methyl]-3-methyl-thiophen-2-yl]carbonylamino]pentanoic acid, Beta-2 adrenergic receptor,C3a anaphylatoxin chemotactic receptor,Soluble cytochrome b562, anti-BRIL Fab HC, ... | Authors: | Luo, P, Xu, Y, Xu, H.E. | Deposit date: | 2024-06-13 | Release date: | 2025-05-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into the agonist activity of the nonpeptide modulator JR14a on C3aR. Cell Discov, 11, 2025
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8ZWG
 
 | cryoEM structure of JR14a bound C3aR-Gi complex | Descriptor: | (2~{S})-5-[bis(azanyl)methylideneamino]-2-[[5-[bis(4-chlorophenyl)methyl]-3-methyl-thiophen-2-yl]carbonylamino]pentanoic acid, Beta-2 adrenergic receptor,C3a anaphylatoxin chemotactic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Luo, P, Xu, Y, Xu, H.E. | Deposit date: | 2024-06-13 | Release date: | 2025-05-14 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Structural insights into the agonist activity of the nonpeptide modulator JR14a on C3aR. Cell Discov, 11, 2025
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8GY7
 
 | Cryo-EM structure of ACTH-bound melanocortin-2 receptor in complex with MRAP1 and Gs protein | Descriptor: | CALCIUM ION, Corticotropin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Luo, P, Feng, W.B, Ma, S.S, Dai, A.T, Yuan, Q.N, Wu, K, Yang, D.H, Wang, M.W, Xu, H.E, Jiang, Y. | Deposit date: | 2022-09-21 | Release date: | 2023-01-11 | Last modified: | 2024-11-13 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of signaling regulation of the human melanocortin-2 receptor by MRAP1. Cell Res., 33, 2023
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3LET
 
 | Crystal Structure of Fic domain containing AMPylator, VopS | Descriptor: | Adenosine monophosphate-protein transferase vopS | Authors: | Luong, P.H, Kinch, L.N, Brautigam, C.A, Grishin, N.V, Tomchick, D.R, Orth, K. | Deposit date: | 2010-01-15 | Release date: | 2010-04-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Structural and Kinetic Analysis of VopS with Fic Domain Supports a Direct Transfer Mechanism for AMPylation To be Published
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