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PDB: 14 件

2AZT
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Crystal structure of H176N mutant of human Glycine N-Methyltransferase
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, CITRIC ACID, ...
著者Luka, Z, Pakhomova, S, Luka, Y, Newcomer, M.E, Wagner, C.
登録日2005-09-12
公開日2006-09-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Destabilization of human glycine N-methyltransferase by H176N mutation.
Protein Sci., 16, 2007
6E1F
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Crystal structure of the SWIRM domain of human histone lysine-specific demethylase LSD1
分子名称: Lysine-specific histone demethylase 1A, SULFATE ION
著者Luka, Z, Pakhomova, S, Reiter, N.J.
登録日2018-07-09
公開日2019-07-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Transient and highly ordered structural domains exist within the N-terminus of LSD1 and differentially interact with mononucleosomes
To be Published
3THS
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Crystal structure of rat native liver Glycine N-methyltransferase complexed with 5-methyltetrahydrofolate pentaglutamate
分子名称: 5-methyltetrahydrofolate pentaglutamate, BETA-MERCAPTOETHANOL, Glycine N-methyltransferase, ...
著者Luka, Z, Pakhomova, S, Loukachevitch, L.V, Newcomer, M.E, Wagner, C.
登録日2011-08-19
公開日2011-11-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Differences in folate-protein interactions result in differing inhibition of native rat liver and recombinant glycine N-methyltransferase by 5-methyltetrahydrofolate.
Biochim.Biophys.Acta, 1824, 2011
4KUM
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Structure of LSD1-CoREST-Tetrahydrofolate complex
分子名称: (6S)-5,6,7,8-TETRAHYDROFOLATE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Luka, Z, Pakhomova, S, Loukachevitch, L.V, Calcutt, M.W, Newcomer, M.E, Wagner, C.
登録日2013-05-22
公開日2014-05-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal structure of the histone lysine specific demethylase LSD1 complexed with tetrahydrofolate.
Protein Sci., 23, 2014
3THR
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Crystal structure of rat native liver Glycine N-methyltransferase complexed with 5-methyltetrahydrofolate monoglutamate
分子名称: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, Glycine N-methyltransferase, TRIS(HYDROXYETHYL)AMINOMETHANE
著者Luka, Z, Pakhomova, S, Loukachevitch, L.V, Newcomer, M.E, Wagner, C.
登録日2011-08-19
公開日2011-11-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Differences in folate-protein interactions result in differing inhibition of native rat liver and recombinant glycine N-methyltransferase by 5-methyltetrahydrofolate.
Biochim.Biophys.Acta, 1824, 2011
4XBF
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Structure of LSD1:CoREST in complex with ssRNA
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ...
著者Luka, Z, Loukachevitch, L.V, Martin, W.J, Wagner, C, Reiter, N.J.
登録日2014-12-16
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献G-quadruplex RNA binding and recognition by the lysine-specific histone demethylase-1 enzyme.
RNA, 22, 2016
2IDK
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Crystal Structure of Rat Glycine N-Methyltransferase Complexed With Folate
分子名称: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, Glycine N-methyltransferase
著者Luka, Z, Pakhomova, S, Loukachevitch, L.V, Egli, M, Newcomer, M.E, Wagner, C.
登録日2006-09-15
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献5-methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferase.
J.Biol.Chem., 282, 2007
2IDJ
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Crystal Structure of Rat Glycine N-Methyltransferase Apoprotein, Monoclinic Form
分子名称: CALCIUM ION, Glycine N-methyltransferase
著者Luka, Z, Pakhomova, S, Loukachevitch, L.V, Egli, M, Newcomer, M.E, Wagner, C.
登録日2006-09-15
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献5-methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferase.
J.Biol.Chem., 282, 2007
4PAA
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Crystal structure of the mature form of rat DMGDH complexed with tetrahydrofolate
分子名称: (6S)-5,6,7,8-TETRAHYDROFOLATE, Dimethylglycine dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE
著者Luka, Z, Pakhomova, S, Loukachevitch, L.V, Newcomer, M.E, Wagner, C.
登録日2014-04-07
公開日2014-06-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Folate in demethylation: The crystal structure of the rat dimethylglycine dehydrogenase complexed with tetrahydrofolate.
Biochem.Biophys.Res.Commun., 449, 2014
4PAB
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Crystal structure of the precursor form of rat DMGDH complexed with tetrahydrofolate
分子名称: (6S)-5,6,7,8-TETRAHYDROFOLATE, Dimethylglycine dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Luka, Z, Pakhomova, S, Loukachevitch, L.V, Newcomer, M.E, Wagner, C.
登録日2014-04-07
公開日2014-06-18
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Folate in demethylation: The crystal structure of the rat dimethylglycine dehydrogenase complexed with tetrahydrofolate.
Biochem.Biophys.Res.Commun., 449, 2014
4P9S
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Crystal structure of the mature form of rat DMGDH
分子名称: Dimethylglycine dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE
著者Luka, Z, Pakhomova, S, Loukachevitch, L.V, Newcomer, M.E, Wagner, C.
登録日2014-04-04
公開日2014-06-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Folate in demethylation: The crystal structure of the rat dimethylglycine dehydrogenase complexed with tetrahydrofolate.
Biochem.Biophys.Res.Commun., 449, 2014
1R8X
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Crystal Structure of Mouse Glycine N-Methyltransferase (Tetragonal Form)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, glycine N-methyltransferase
著者Pakhomova, S, Luka, Z, Wagner, C, Newcomer, M.E.
登録日2003-10-28
公開日2004-09-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.
Proteins, 57, 2004
1R8Y
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Crystal Structure of Mouse Glycine N-Methyltransferase (Monoclinic Form)
分子名称: BETA-MERCAPTOETHANOL, glycine N-methyltransferase
著者Pakhomova, S, Luka, Z, Wagner, C, Newcomer, M.E.
登録日2003-10-28
公開日2004-09-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.
Proteins, 57, 2004
1R74
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Crystal Structure of Human Glycine N-Methyltransferase
分子名称: BETA-MERCAPTOETHANOL, CITRIC ACID, Glycine N-methyltransferase
著者Pakhomova, S, Luka, Z, Wagner, C, Newcomer, M.E.
登録日2003-10-17
公開日2004-09-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.
Proteins, 57, 2004

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件を2024-11-06に公開中

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