7P03
 
 | | Cryo-EM structure of Pdr5 from Saccharomyces cerevisiae in inward-facing conformation without nucleotides | | Descriptor: | Pleiotropic ABC efflux transporter of multiple drugs | | Authors: | Szewczak-Harris, A, Wagner, M, Du, D, Schmitt, L, Luisi, B.F. | | Deposit date: | 2021-06-29 | | Release date: | 2021-11-10 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5.
Nat Commun, 12, 2021
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4O7J
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4OWG
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8BVM
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3GME
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8BVH
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3GLL
 | | Crystal structure of Polynucleotide Phosphorylase (PNPase) core | | Descriptor: | Polyribonucleotide nucleotidyltransferase | | Authors: | Nurmohamed, S, Luisi, B.L. | | Deposit date: | 2009-03-12 | | Release date: | 2009-06-09 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of Escherichia coli polynucleotide phosphorylase core bound to RNase E, RNA and manganese: implications for catalytic mechanism and RNA degradosome assembly.
J.Mol.Biol., 389, 2009
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1W88
 | | The crystal structure of pyruvate dehydrogenase E1(D180N,E183Q) bound to the peripheral subunit binding domain of E2 | | Descriptor: | DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE, MAGNESIUM ION, PYRUVATE DEHYDROGENASE E1 COMPONENT, ... | | Authors: | Frank, R.A.W, Pratap, J.V, Pei, X.Y, Perham, R.N, Luisi, B.F. | | Deposit date: | 2004-09-16 | | Release date: | 2004-11-02 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A Molecular Switch and Proton-Wire Synchronize the Active Sites in Thiamine-Dependent Enzymes
Science, 306, 2004
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2YJN
 | | Structure of the glycosyltransferase EryCIII from the erythromycin biosynthetic pathway, in complex with its activating partner, EryCII | | Descriptor: | DTDP-4-KETO-6-DEOXY-HEXOSE 3,4-ISOMERASE, GLYCOSYLTRANSFERASE | | Authors: | Moncrieffe, M.C, Fernandez, M.J, Spiteller, D, Matsumura, H, Gay, N.J, Luisi, B.F, Leadlay, P.F. | | Deposit date: | 2011-05-20 | | Release date: | 2011-11-09 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.091 Å) | | Cite: | Structure of the Glycosyltransferase Eryciii in Complex with its Activating P450 Homologue Erycii.
J.Mol.Biol., 415, 2012
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1P7I
 | | CRYSTAL STRUCTURE OF ENGRAILED HOMEODOMAIN MUTANT K52A | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | | Authors: | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | | Deposit date: | 2003-05-02 | | Release date: | 2003-10-14 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS
J.Biol.Chem., 278, 2003
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1W85
 | | The crystal structure of pyruvate dehydrogenase E1 bound to the peripheral subunit binding domain of E2 | | Descriptor: | DI(HYDROXYETHYL)ETHER, DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE, MAGNESIUM ION, ... | | Authors: | Frank, R.A.W, Pratap, J.V, Pei, X.Y, Perham, R.N, Luisi, B.F. | | Deposit date: | 2004-09-16 | | Release date: | 2004-11-02 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A molecular switch and proton wire synchronize the active sites in thiamine enzymes.
Science, 306, 2004
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1P7J
 | | Crystal structure of engrailed homeodomain mutant K52E | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | | Authors: | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | | Deposit date: | 2003-05-02 | | Release date: | 2003-10-14 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS
J.Biol.Chem., 278, 2003
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2FIC
 | | The crystal structure of the BAR domain from human Bin1/Amphiphysin II and its implications for molecular recognition | | Descriptor: | Myc box-dependent-interacting protein 1, XENON | | Authors: | Casal, E, Federici, L, Zhang, W, Fernandez-Recio, J, Priego, E.M, Miguel, R.N, Duhadaway, J.B, Prendergast, G.C, Luisi, B.F, Laue, E.D. | | Deposit date: | 2005-12-29 | | Release date: | 2006-11-14 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | The Crystal Structure of the BAR Domain from Human Bin1/Amphiphysin II and Its Implications for Molecular Recognition
Biochemistry, 45, 2006
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4QKK
 | | Crystal structure of an oligonucleotide containing 5-formylcytosine | | Descriptor: | DNA (5'-D(*CP*TP*AP*(5FC)P*GP*(5FC)P*GP*(5FC)P*GP*TP*AP*G)-3') | | Authors: | Raiber, E.-A, Murat, P, Chirgadze, D.Y, Luisi, B.F, Balasubramanian, S. | | Deposit date: | 2014-06-06 | | Release date: | 2014-12-10 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | 5-Formylcytosine alters the structure of the DNA double helix.
Nat.Struct.Mol.Biol., 22, 2015
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1TRO
 | | CRYSTAL STRUCTURE OF TRP REPRESSOR OPERATOR COMPLEX AT ATOMIC RESOLUTION | | Descriptor: | DNA (5'-D(*TP*GP*TP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*TP*AP*GP*T P*AP*C)-3'), PROTEIN (TRP REPRESSOR), TRYPTOPHAN | | Authors: | Otwinowski, Z, Schevitz, R.W, Zhang, R.-G, Lawson, C.L, Joachimiak, A, Marmorstein, R, Luisi, B.F, Sigler, P.B. | | Deposit date: | 1992-08-30 | | Release date: | 1994-01-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of trp repressor/operator complex at atomic resolution.
Nature, 335, 1988
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352D
 | | THE CRYSTAL STRUCTURE OF A PARALLEL-STRANDED PARALLEL-STRANDED GUANINE TETRAPLEX AT 0.95 ANGSTROM RESOLUTION | | Descriptor: | CALCIUM ION, DNA (5'-D(*TP*GP*GP*GP*GP*T)-3'), SODIUM ION | | Authors: | Phillips, K, Dauter, Z, Murchie, A.I.H, Lilley, D.M.J, Luisi, B. | | Deposit date: | 1997-09-04 | | Release date: | 1997-11-10 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (0.95 Å) | | Cite: | The crystal structure of a parallel-stranded guanine tetraplex at 0.95 A resolution.
J.Mol.Biol., 273, 1997
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2YJV
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2YJT
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2JGD
 | | E. COLI 2-oxoglutarate dehydrogenase (E1o) | | Descriptor: | 2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT, ADENOSINE MONOPHOSPHATE | | Authors: | Frank, R.A.W, Price, A.J, Northrop, F.D, Perham, R.N, Luisi, B.F. | | Deposit date: | 2007-02-12 | | Release date: | 2007-02-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of the E1 Component of the Escherichia Coli 2-Oxoglutarate Dehydrogenase Multienzyme Complex.
J.Mol.Biol., 368, 2007
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2FYM
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8CGL
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3H8A
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1W08
 | | STRUCTURE OF T70N HUMAN LYSOZYME | | Descriptor: | CHLORIDE ION, LYSOZYME | | Authors: | Johnson, R, Christodoulou, J, Luisi, B, Dumoulin, M, Caddy, G, Alcocer, M, Murtagh, G, Archer, D.B, Dobson, C.M. | | Deposit date: | 2004-06-02 | | Release date: | 2004-06-10 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Rationalising Lysozyme Amyloidosis: Insights from the Structure and Solution Dynamics of T70N Lysozyme.
J.Mol.Biol., 352, 2005
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5NC5
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8CBM
 | | Structure of human mitochondrial CCA-adding enzyme in complex with mitochondrial pre-tRNA-Ile | | Descriptor: | 3-hydroxyacyl-CoA dehydrogenase type-2, CCA tRNA nucleotidyltransferase 1, mitochondrial, ... | | Authors: | MEYNIER, V, HARDWICK, S, CATALA, M, ROSKE, J, OERUM, S, CHIRGADZE, D, BARRAUD, P, LUISI, B, TISNE, C. | | Deposit date: | 2023-01-25 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.14 Å) | | Cite: | Structural basis for human mitochondrial tRNA maturation.
Nat Commun, 15, 2024
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