7P03
Cryo-EM structure of Pdr5 from Saccharomyces cerevisiae in inward-facing conformation without nucleotides
Summary for 7P03
| Entry DOI | 10.2210/pdb7p03/pdb |
| EMDB information | 13142 |
| Descriptor | Pleiotropic ABC efflux transporter of multiple drugs (1 entity in total) |
| Functional Keywords | abc transporter, antibiotic resistance, membrane protein, fungal infection, transport protein |
| Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| Total number of polymer chains | 1 |
| Total formula weight | 170617.25 |
| Authors | Szewczak-Harris, A.,Wagner, M.,Du, D.,Schmitt, L.,Luisi, B.F. (deposition date: 2021-06-29, release date: 2021-11-10) |
| Primary citation | Harris, A.,Wagner, M.,Du, D.,Raschka, S.,Nentwig, L.M.,Gohlke, H.,Smits, S.H.J.,Luisi, B.F.,Schmitt, L. Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5. Nat Commun, 12:5254-5254, 2021 Cited by PubMed: 34489436DOI: 10.1038/s41467-021-25574-8 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.45 Å) |
Structure validation
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