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PDB: 171 results

3BXM
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BU of 3bxm by Molmil
Structure of an inactive mutant of human glutamate carboxypeptidase II [GCPII(E424A)] in complex with N-acetyl-Asp-Glu (NAAG)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Lubkowski, J, Barinka, C.
Deposit date:2008-01-14
Release date:2009-01-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Reaction mechanism of glutamate carboxypeptidase II revealed by mutagenesis, X-ray crystallography, and computational methods.
Biochemistry, 48, 2009
5L04
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BU of 5l04 by Molmil
STRUCTURE OF INTERFERON LAMBDA 1 RECEPTOR WITH HUMAN KINASE JAK1
Descriptor: Interferon lambda receptor 1, Tyrosine-protein kinase JAK1
Authors:Lubkowski, J, Wlodawer, A, Zhang, D.
Deposit date:2016-07-26
Release date:2016-10-12
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of a Complex of the Intracellular Domain of Interferon lambda Receptor 1 (IFNLR1) and the FERM/SH2 Domains of Human JAK1.
J. Mol. Biol., 428, 2016
8F1F
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BU of 8f1f by Molmil
Structure of K48-linked tri-ubiquitin in complex with cyclic peptide
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Non-proteinogenic cyclic peptide (inhibitor), ...
Authors:Lubkowski, J, Fushman, D, Lemma, B.
Deposit date:2022-11-05
Release date:2023-11-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation.
Nat Commun, 14, 2023
5T5O
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BU of 5t5o by Molmil
LECTIN FROM BAUHINIA FORFICATA IN COMPLEX WITH TN-PEPTIDE
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, CALCIUM ION, Lectin, ...
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2016-08-31
Release date:2016-12-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural analysis and unique molecular recognition properties of a Bauhinia forficata lectin that inhibits cancer cell growth.
FEBS J., 284, 2017
6DF3
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BU of 6df3 by Molmil
Crystal structure of ternary complex of IL-24 with soluble receptors IL-22RA and IL-20RB
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2018-05-14
Release date:2018-08-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of the Labile Complex of IL-24 with the Extracellular Domains of IL-22R1 and IL-20R2.
J. Immunol., 201, 2018
5DUY
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BU of 5duy by Molmil
Structure of lectin from the sea mussel Crenomytilus grayanus
Descriptor: GLYCEROL, GalNAc/Gal-specific lectin
Authors:Lubkowski, J, Jakob, M, O'Keefe, B, Wlodawer, A.
Deposit date:2015-09-21
Release date:2015-11-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structure of a lectin from the sea mussel Crenomytilus grayanus (CGL).
Acta Crystallogr.,Sect.F, 71, 2015
2RA4
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BU of 2ra4 by Molmil
Crystal Structure of Human Monocyte Chemoattractant Protein 4 (MCP-4/CCL13)
Descriptor: SULFATE ION, Small-inducible cytokine A13, trifluoroacetic acid
Authors:Lubkowski, J, Barinka, C.
Deposit date:2007-09-14
Release date:2008-03-18
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of human monocyte chemoattractant protein 4 (MCP-4/CCL13).
Acta Crystallogr.,Sect.D, 64, 2008
3NR6
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BU of 3nr6 by Molmil
Crystal structure of xenotropic murine leukemia virus-related virus (XMRV) protease
Descriptor: PHOSPHATE ION, POTASSIUM ION, Protease p14
Authors:Lubkowski, J, Li, M, Gustchina, A, Zhou, D, Dauter, Z, Wlodawer, A.
Deposit date:2010-06-30
Release date:2011-02-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystal structure of XMRV protease differs from the structures of other retropepsins.
Nat.Struct.Mol.Biol., 18, 2011
3PGA
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BU of 3pga by Molmil
STRUCTURAL CHARACTERIZATION OF PSEUDOMONAS 7A GLUTAMINASE-ASPARAGINASE
Descriptor: GLUTAMINASE-ASPARAGINASE
Authors:Lubkowski, J, Wlodawer, A, Ammon, H.L, Copeland, T.D, Swain, A.L.
Deposit date:1994-07-19
Release date:1994-12-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural characterization of Pseudomonas 7A glutaminase-asparaginase.
Biochemistry, 33, 1994
1HFK
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BU of 1hfk by Molmil
Asparaginase from Erwinia chrysanthemi, hexagonal form with weak sulfate
Descriptor: L-ASPARAGINE AMIDOHYDROLASE, SULFATE ION
Authors:Lubkowski, J, Palm, G.J, Kozak, M, Jaskolski, M, Wlodawer, A.
Deposit date:2000-12-05
Release date:2000-12-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structures of Two Highly Homologous Bacterial L-Asparaginases: A Case of Enantiomorphic Space Groups
Acta Crystallogr.,Sect.D, 57, 2001
1HG1
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BU of 1hg1 by Molmil
X-ray structure of the complex between Erwinia chrysanthemi L-asparaginase and D-aspartate
Descriptor: D-ASPARTIC ACID, L-ASPARAGINASE
Authors:Lubkowski, J, Wlodawer, A, Kolyani, K.A.
Deposit date:2000-12-08
Release date:2001-08-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Stuctural Basis for the Activity and Substrate Specificity of Erwinia Chrysanthemi L-Asparaginase
Biochemistry, 40, 2001
1HG0
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BU of 1hg0 by Molmil
X-ray structure of the complex between Erwinia chrysanthemi L-asparaginase and succinic acid
Descriptor: L-ASPARAGINASE, SUCCINIC ACID
Authors:Lubkowski, J, Wlodawer, A, Kolyani, K.A.
Deposit date:2000-12-08
Release date:2001-08-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Stuctural Basis for the Activity and Substrate Specificity of Erwinia Chrysanthemi L-Asparaginase
Biochemistry, 40, 2001
3HJ2
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BU of 3hj2 by Molmil
Crystal structure of covalent dimer of HNP1
Descriptor: HUMAN NEUTROPHIL PEPTIDE 1
Authors:Lubkowski, J, Pazgier, M, Lu, W.
Deposit date:2009-05-20
Release date:2009-10-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:What Dictates the Multifaced Functions of the Human alpha-Defensin HNP1?
To be Published
3HJD
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BU of 3hjd by Molmil
X-ray structure of monomeric variant of HNP1
Descriptor: Human neutrophil peptide 1
Authors:Lubkowski, J, Pazgier, M, Lu, W.
Deposit date:2009-05-21
Release date:2009-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:What Dictates the Multifaced Functions of the Human alpha-Defensin HNP?
To be Published
1TOL
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BU of 1tol by Molmil
FUSION OF N-TERMINAL DOMAIN OF THE MINOR COAT PROTEIN FROM GENE III IN PHAGE M13, AND C-TERMINAL DOMAIN OF E. COLI PROTEIN-TOLA
Descriptor: PROTEIN (FUSION PROTEIN CONSISTING OF MINOR COAT PROTEIN, GLYCINE RICH LINKER, TOLA, ...
Authors:Lubkowski, J, Wlodawer, A, Hennecke, F, Plueckthun, A.
Deposit date:1999-05-17
Release date:1999-05-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Filamentous phage infection: crystal structure of g3p in complex with its coreceptor, the C-terminal domain of TolA.
Structure Fold.Des., 7, 1999
1AGX
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BU of 1agx by Molmil
REFINED CRYSTAL STRUCTURE OF ACINETOBACTER GLUTAMINASIFICANS GLUTAMINASE-ASPARAGINASE
Descriptor: GLUTAMINASE-ASPARAGINASE
Authors:Lubkowski, J, Wlodawer, A, Housset, D, Weber, I.T, Ammon, H.L, Murphy, K.C, Swain, A.L.
Deposit date:1994-07-13
Release date:1994-12-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Refined crystal structure of Acinetobacter glutaminasificans glutaminase-asparaginase.
Acta Crystallogr.,Sect.D, 50, 1994
6NX9
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BU of 6nx9 by Molmil
ECAII(D90T,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 7
Descriptor: ACETIC ACID, GLYCEROL, IMIDAZOLE, ...
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions.
Sci Rep, 9, 2019
6NXB
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BU of 6nxb by Molmil
ECAII IN COMPLEX WITH CITRATE AT PH 7
Descriptor: CITRIC ACID, GLYCEROL, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions.
Sci Rep, 9, 2019
6NX6
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BU of 6nx6 by Molmil
ECAII(D90T,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 5
Descriptor: ACETIC ACID, CITRIC ACID, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions.
Sci Rep, 9, 2019
6NXD
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BU of 6nxd by Molmil
TYPE I L-ASPARAGINASE FROM ESCHERICHIA COLI IN COMPLEX WITH CITRATE AT PH 4
Descriptor: 1,2-ETHANEDIOL, ASPARAGINE, CHLORIDE ION, ...
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Last modified:2020-01-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions.
Sci Rep, 9, 2019
6NX8
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BU of 6nx8 by Molmil
ECAII(D90T,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 6.2
Descriptor: ACETIC ACID, CITRIC ACID, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions.
Sci Rep, 9, 2019
6NX7
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BU of 6nx7 by Molmil
ECAII(D90T,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 5.6
Descriptor: ACETIC ACID, CITRIC ACID, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions.
Sci Rep, 9, 2019
6NXA
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BU of 6nxa by Molmil
ECAII(D90T,K162T) MUTANT AT PH 7
Descriptor: ACETIC ACID, GLYCEROL, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Last modified:2020-08-19
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions.
Sci Rep, 9, 2019
6NXC
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BU of 6nxc by Molmil
ECAI(T162A) MUTANT IN COMPLEX WITH CITRATE AT PH 4
Descriptor: 1,2-ETHANEDIOL, ASPARAGINE, CHLORIDE ION, ...
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions.
Sci Rep, 9, 2019
3BI0
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BU of 3bi0 by Molmil
X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a transition state analog of Glu-Glu
Descriptor: (2S)-2-{[(S)-[(3S)-3-amino-3-carboxypropyl](hydroxy)phosphoryl]methyl}pentanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lubkowski, J, Barinka, C.
Deposit date:2007-11-29
Release date:2008-01-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural basis of interactions between human glutamate carboxypeptidase II and its substrate analogs
J.Mol.Biol., 376, 2008

226707

數據於2024-10-30公開中

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