5L04
STRUCTURE OF INTERFERON LAMBDA 1 RECEPTOR WITH HUMAN KINASE JAK1
Summary for 5L04
Entry DOI | 10.2210/pdb5l04/pdb |
Descriptor | Tyrosine-protein kinase JAK1, Interferon lambda receptor 1 (3 entities in total) |
Functional Keywords | complex of jak1 and interferon lambda 1, jak kinase, intracellular domain of ifnlr1, ferm domain, sh2-like domain, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Endomembrane system; Peripheral membrane protein: P23458 Membrane ; Single-pass type I membrane protein : Q8IU57 |
Total number of polymer chains | 2 |
Total formula weight | 69430.31 |
Authors | Lubkowski, J.,Wlodawer, A.,Zhang, D. (deposition date: 2016-07-26, release date: 2016-10-12, Last modification date: 2024-03-06) |
Primary citation | Zhang, D.,Wlodawer, A.,Lubkowski, J. Crystal Structure of a Complex of the Intracellular Domain of Interferon lambda Receptor 1 (IFNLR1) and the FERM/SH2 Domains of Human JAK1. J. Mol. Biol., 428:4651-4668, 2016 Cited by PubMed: 27725180DOI: 10.1016/j.jmb.2016.10.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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