1EVJ
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![BU of 1evj by Molmil](/molmil-images/mine/1evj) | CRYSTAL STRUCTURE OF GLUCOSE-FRUCTOSE OXIDOREDUCTASE (GFOR) DELTA1-22 S64D | Descriptor: | GLUCOSE-FRUCTOSE OXIDOREDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Lott, J.S, Halbig, D, Baker, H.M, Hardman, M.J, Sprenger, G.A, Baker, E.N. | Deposit date: | 2000-04-20 | Release date: | 2000-12-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of a truncated mutant of glucose-fructose oxidoreductase shows that an N-terminal arm controls tetramer formation. J.Mol.Biol., 304, 2000
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2GL0
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![BU of 2gl0 by Molmil](/molmil-images/mine/2gl0) | Structure of PAE2307 in complex with adenosine | Descriptor: | ADENOSINE, PHOSPHATE ION, conserved hypothetical protein | Authors: | Lott, J.S, Paget, B, Johnston, J.M, Baker, E.N. | Deposit date: | 2006-04-04 | Release date: | 2006-06-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The Structure of an Ancient Conserved Domain Establishes a Structural Basis for Stable Histidine Phosphorylation and Identifies a New Family of Adenosine-specific Kinases. J.Biol.Chem., 281, 2006
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1WVQ
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![BU of 1wvq by Molmil](/molmil-images/mine/1wvq) | Structure of conserved hypothetical protein PAE2307 from Pyrobaculum aerophilum | Descriptor: | PHOSPHATE ION, hypothetical protein PAE2307 | Authors: | Lott, J.S, Delbaere, L.T, Banfield, M.J, Sigrell-Simon, J.A, Baker, E.N. | Deposit date: | 2004-12-24 | Release date: | 2006-01-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The structure of an ancient conserved domain establishes a structural basis for stable histidine phosphorylation and identifies a new family of adenosine-specific kinases. J.Biol.Chem., 281, 2006
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4NF7
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![BU of 4nf7 by Molmil](/molmil-images/mine/4nf7) | |
2G5F
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![BU of 2g5f by Molmil](/molmil-images/mine/2g5f) | The structure of MbtI from Mycobacterium Tuberculosis, the first enzyme in the synthesis of Mycobactin, reveals it to be a salicylate synthase | Descriptor: | COG0147: Anthranilate/para-aminobenzoate synthases component I, GLYCEROL, IMIDAZOLE, ... | Authors: | Harrison, A.J, Lott, J.S, Yu, M, Ramsay, R, Baker, E.N, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2006-02-22 | Release date: | 2006-09-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Structure of MbtI from Mycobacterium tuberculosis, the First Enzyme in the Biosynthesis of the Siderophore Mycobactin, Reveals It To Be a Salicylate Synthase J.Bacteriol., 188, 2006
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4OWQ
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![BU of 4owq by Molmil](/molmil-images/mine/4owq) | Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 3-methylanthranilate, PRPP and Magnesium | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-azanyl-3-methyl-benzoic acid, Anthranilate phosphoribosyltransferase, ... | Authors: | Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S. | Deposit date: | 2014-02-03 | Release date: | 2014-04-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis. Biochem.J., 461, 2014
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4OWV
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![BU of 4owv by Molmil](/molmil-images/mine/4owv) | Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with anthranilate | Descriptor: | 2-AMINOBENZOIC ACID, Anthranilate phosphoribosyltransferase, GLYCEROL, ... | Authors: | Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S. | Deposit date: | 2014-02-04 | Release date: | 2014-04-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis. Biochem.J., 461, 2014
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4W1U
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2M3O
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![BU of 2m3o by Molmil](/molmil-images/mine/2m3o) | Structure and dynamics of a human Nedd4 WW domain-ENaC complex | Descriptor: | Amiloride-sensitive sodium channel subunit alpha, E3 ubiquitin-protein ligase NEDD4 | Authors: | Bobby, R, Medini, K, Neudecker, P, Lee, V, MacDonald, F.J, Brimble, M.A, Lott, J, Dingley, A.J. | Deposit date: | 2013-01-23 | Release date: | 2013-08-28 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure and dynamics of human Nedd4-1 WW3 in complex with the alpha ENaC PY motif. Biochim.Biophys.Acta, 1834, 2013
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5FCC
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![BU of 5fcc by Molmil](/molmil-images/mine/5fcc) | Structure of HutD from Pseudomonas fluorescens SBW25 (NaCl condition) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, HutD, ... | Authors: | Johnston, J.M, Gerth, M.L, Baker, E.N, Lott, J.S, Rainey, P.B. | Deposit date: | 2015-12-15 | Release date: | 2017-01-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structure of HutD from Pseudomonas fluorescens To Be Published
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4DWS
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3ITE
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![BU of 3ite by Molmil](/molmil-images/mine/3ite) | The third adenylation domain of the fungal SidN non-ribosomal peptide synthetase | Descriptor: | CHLORIDE ION, SULFATE ION, SidN siderophore synthetase | Authors: | Lee, T.V, Lott, J.S, Johnson, R.D, Johnson, L.J, Arcus, V.L. | Deposit date: | 2009-08-28 | Release date: | 2009-11-17 | Last modified: | 2014-02-05 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a eukaryotic nonribosomal peptide synthetase adenylation domain that activates a large hydroxamate amino acid in siderophore biosynthesis J.Biol.Chem., 285, 2010
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6VTJ
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6VTZ
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5KIS
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![BU of 5kis by Molmil](/molmil-images/mine/5kis) | YenB/RHS2 complex | Descriptor: | CALCIUM ION, CHLORIDE ION, RHS2, ... | Authors: | Busby, J.N, Hurst, M.R.H, Lott, J.S. | Deposit date: | 2016-06-16 | Release date: | 2017-08-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of a new BC complex from Yersinia entomophaga To Be Published
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2B7O
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![BU of 2b7o by Molmil](/molmil-images/mine/2b7o) | The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase from Mycobacterium tuberculosis | Descriptor: | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, MANGANESE (II) ION, O-DODECANYL OCTAETHYLENE GLYCOL, ... | Authors: | Webby, C.J, Baker, H.M, Lott, J.S, Baker, E.N, Parker, E.J, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | Deposit date: | 2005-10-05 | Release date: | 2005-10-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes J.Mol.Biol., 354, 2005
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6AQK
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2BPQ
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![BU of 2bpq by Molmil](/molmil-images/mine/2bpq) | Anthranilate phosphoribosyltransferase (TrpD) from Mycobacterium tuberculosis (Apo structure) | Descriptor: | ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE, BENZAMIDINE, GLYCEROL | Authors: | Lee, C.E, Goodfellow, C, Javid-Majd, F, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2005-04-22 | Release date: | 2006-01-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Crystal Structure of Trpd, a Metabolic Enzyme Essential for Lung Colonization by Mycobacterium Tuberculosis, in Complex with its Substrate Phosphoribosylpyrophosphate J.Mol.Biol., 355, 2006
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5V00
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![BU of 5v00 by Molmil](/molmil-images/mine/5v00) | Structure of HutD from Pseudomonas fluorescens SBW25 (Formate condition) | Descriptor: | FORMIC ACID, GLYCEROL, Uncharacterized protein | Authors: | Liu, Y, Johnston, J.M, Gerth, M.L, Baker, E.N, Lott, J.S, Rainey, P.B. | Deposit date: | 2017-02-27 | Release date: | 2017-03-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of a bicupin protein HutD involved in histidine utilization in Pseudomonas. Proteins, 85, 2017
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2JB7
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![BU of 2jb7 by Molmil](/molmil-images/mine/2jb7) | PAE2307 with AMP | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ADENOSINE MONOPHOSPHATE, ... | Authors: | Rajasekaran, K, Lott, J.S, Johnston, J.M. | Deposit date: | 2006-12-04 | Release date: | 2008-08-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Pae2307 a Phosphotransferase To be Published
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1H5Y
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![BU of 1h5y by Molmil](/molmil-images/mine/1h5y) | HisF protein from Pyrobaculum aerophilum | Descriptor: | GLYCEROL, HISF, PHOSPHATE ION | Authors: | Banfield, M.J, Lott, J.S, McCarthy, A.A, Baker, E.N. | Deposit date: | 2001-05-31 | Release date: | 2001-06-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of Hisf, a Histidine Biosynthetic Protein from Pyrobaculum Aerophilum Acta Crystallogr.,Sect.D, 57, 2001
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5UA1
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![BU of 5ua1 by Molmil](/molmil-images/mine/5ua1) | Mycobacterium tuberculosis KstR in complex with a 18-bp DNA operator | Descriptor: | DNA (5'-D(*AP*CP*TP*AP*GP*AP*AP*CP*GP*TP*GP*TP*TP*CP*TP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*AP*GP*AP*AP*CP*AP*CP*GP*TP*TP*CP*TP*AP*GP*T)-3'), HTH-type transcriptional repressor KstR, ... | Authors: | Ho, N.A.T, Dawes, S.S, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2016-12-18 | Release date: | 2017-11-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of KstR in complex with cognate DNA operator To Be Published
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4A5Q
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![BU of 4a5q by Molmil](/molmil-images/mine/4a5q) | Crystal structure of the chitinase Chi1 fitted into the 3D structure of the Yersinia entomophaga toxin complex | Descriptor: | CHI1 | Authors: | Busby, J.N, Landsberg, M.J, Simpson, R.M, Jones, S.A, Hankamer, B, Hurst, M.R.H, Lott, J.S. | Deposit date: | 2011-10-27 | Release date: | 2011-11-16 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (17 Å) | Cite: | Structural Analysis of Chi1 Chitinase from Yen-Tc: The Multisubunit Insecticidal Abc Toxin Complex of Yersinia Entomophaga. J.Mol.Biol., 415, 2012
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3VEH
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![BU of 3veh by Molmil](/molmil-images/mine/3veh) | Structure of a M. tuberculosis salicylate synthase, MbtI, in complex with an inhibitor methylAMT | Descriptor: | 3-{[(1Z)-1-carboxyprop-1-en-1-yl]oxy}-2-hydroxybenzoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Bulloch, E.M, Chi, G, Manos-Turvey, A, Johnston, J.M, Baker, E.N, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2012-01-08 | Release date: | 2012-06-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis. Biochemistry, 51, 2012
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3OA5
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![BU of 3oa5 by Molmil](/molmil-images/mine/3oa5) | The structure of chi1, a chitinase from Yersinia entomophaga | Descriptor: | Chi1, GLYCEROL, NONAETHYLENE GLYCOL | Authors: | Busby, J.N, Lott, J.S, Hurst, M.R.H. | Deposit date: | 2010-08-04 | Release date: | 2011-08-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structural analysis of Chi1 Chitinase from Yen-Tc: the multisubunit insecticidal ABC toxin complex of Yersinia entomophaga J.Mol.Biol., 415, 2012
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