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PDB: 64 件

5W7X
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Crystal Structure of FHA domain of human APLF in complex with XRCC1 bisphospho peptide
分子名称: Aprataxin and PNK-like factor, DNA repair protein XRCC1
著者Pedersen, L.C, Kim, K, London, R.E.
登録日2017-06-21
公開日2018-05-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.005 Å)
主引用文献Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.
Nucleic Acids Res., 45, 2017
1QVX
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SOLUTION STRUCTURE OF THE FAT DOMAIN OF FOCAL ADHESION KINASE
分子名称: Focal adhesion kinase 1
著者Gao, G, Prutzman, K.C, King, M.L, DeRose, E.F, London, R.E, Schaller, M.D, Campbell, S.L.
登録日2003-08-29
公開日2004-03-02
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献NMR Solution Structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase in Complex with a Paxillin LD Peptide: EVIDENCE FOR A TWO-SITE BINDING MODEL.
J.Biol.Chem., 279, 2004
6VCJ
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Crystal structure of hsDHFR in complex with NADP+, DAP, and R-naproxen
分子名称: (2R)-2-(6-methoxynaphthalen-2-yl)propanoic acid, Dihydrofolate reductase, FOLIC ACID, ...
著者Pedersen, L.C, London, R.E, Gabel, S.A, Krahn, J.M, DeRose, E.F.
登録日2019-12-21
公開日2020-10-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase.
J.Med.Chem., 63, 2020
4EHQ
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Crystal Structure of Calmodulin Binding Domain of Orai1 in Complex with Ca2+/Calmodulin Displays a Unique Binding Mode
分子名称: CALCIUM ION, Calcium release-activated calcium channel protein 1, Calmodulin, ...
著者Liu, Y, Zheng, X, Mueller, G.A, Sobhany, M, DeRose, E.F, Zhang, Y, London, R.E, Birnbaumer, L.
登録日2012-04-03
公開日2012-11-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9005 Å)
主引用文献Crystal structure of calmodulin binding domain of orai1 in complex with ca2+*calmodulin displays a unique binding mode.
J.Biol.Chem., 287, 2012
2A31
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Trypsin in complex with borate
分子名称: BORATE ION, CALCIUM ION, GUANIDINE-3-PROPANOL, ...
著者Transue, T.R, Gabel, S.A, London, R.E.
登録日2005-06-23
公開日2006-07-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献NMR and crystallographic characterization of adventitious borate binding by trypsin.
Bioconjug.Chem., 17, 2006
2A32
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Trypsin in complex with benzene boronic acid
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, BORATE ION, CALCIUM ION, ...
著者Transue, T.R, Gabel, S.A, London, R.E.
登録日2005-06-23
公開日2006-07-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献NMR and crystallographic characterization of adventitious borate binding by trypsin.
Bioconjug.Chem., 17, 2006
4ZCE
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Crystal Structure of the dust mite allergen Der p 23 from Dermatophagoides pteronyssinus
分子名称: 1,2-ETHANEDIOL, Dust mite allergen
著者Pedersen, L.C, Mueller, G.A, Randall, T.A, Glesner, J, Perera, L, Edwards, L.L, Chapman, M.D, London, R.E, Pomes, A.
登録日2015-04-15
公開日2015-11-25
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Serological, genomic and structural analyses of the major mite allergen Der p 23.
Clin Exp Allergy, 46, 2016
1ZM8
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Apo Crystal structure of Nuclease A from Anabaena sp.
分子名称: MANGANESE (II) ION, Nuclease, SODIUM ION, ...
著者Ghosh, M, Meiss, G, Pingoud, A, London, R.E, Pedersen, L.C.
登録日2005-05-10
公開日2005-06-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insights into the Mechanism of Nuclease A, a beta beta alpha Metal Nuclease from Anabaena.
J.Biol.Chem., 280, 2005
2AE9
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Solution Structure of the theta subunit of DNA polymerase III from E. coli
分子名称: DNA polymerase III, theta subunit
著者Mueller, G.A, Kirby, T.W, Derose, E.F, Li, D, Schaaper, R.M, London, R.E.
登録日2005-07-21
公開日2005-10-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Nuclear Magnetic Resonance Solution Structure of the Escherichia coli DNA Polymerase III {theta} Subunit.
J.Bacteriol., 187, 2005
8TCK
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Apo crystal Structure of modified HIV reverse transcriptase p51 domain (FPC1)
分子名称: p51 subunit
著者Pedersen, L.C, London, R.E.
登録日2023-07-02
公開日2024-07-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Apo crystal Structure of modified HIV reverse transcriptase p51 domain (FPC2)
To Be Published
8TCL
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Crystal Structure of modified HIV reverse transcriptase p51 domain (FPC2) with picrate bound
分子名称: PICRIC ACID, p51 subunit
著者Pedersen, L.C, London, R.E.
登録日2023-07-02
公開日2024-07-17
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Apo crystal Structure of modified HIV reverse transcriptase p51 domain (FPC2)
To Be Published
8TCJ
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Apo crystal Structure of modified HIV reverse transcriptase p51 domain (FPC2)
分子名称: p51 subunit
著者Pedersen, L.C, London, R.E.
登録日2023-07-02
公開日2024-07-17
実験手法X-RAY DIFFRACTION (1.848 Å)
主引用文献Apo crystal Structure of modified HIV reverse transcriptase p51 domain (FPC2)
To Be Published
8TCM
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Crystal Structure of modified HIV reverse transcriptase p51 domain (FPC1) with picric acid and Xanthene-1,3,6,8-tetrol bound
分子名称: 9H-xanthene-1,3,6,8-tetrol, PICRIC ACID, p51 subunit
著者Pedersen, L.C, London, R.E.
登録日2023-07-02
公開日2024-07-17
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal Structure of modified HIV reverse transcriptase p51 domain (FPC1) with picric acid and xanthene bound
To Be Published
4OUO
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anti-Bla g 1 scFv
分子名称: CHLORIDE ION, SULFATE ION, anti Bla g 1 scFv
著者Mueller, G.A, Ankney, J.A, Glesner, J, Khurana, T, Edwards, L.L, Pedersen, L.C, Perera, L, Slater, J.E, Pomes, A, London, R.E.
登録日2014-02-18
公開日2014-03-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Characterization of an anti-Bla g 1 scFv: Epitope mapping and cross-reactivity.
Mol.Immunol., 59, 2014
4X9E
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DEOXYGUANOSINETRIPHOSPHATE TRIPHOSPHOHYDROLASE from Escherichia coli with two DNA effector molecules
分子名称: Deoxyguanosinetriphosphate triphosphohydrolase, MAGNESIUM ION, RNA (5'-R(P*CP*CP*C)-3')
著者Singh, D, Gawel, D, Itsko, M, Krahn, J.M, London, R.E, Schaaper, R.M.
登録日2014-12-11
公開日2015-02-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of Escherichia coli dGTP Triphosphohydrolase: A HEXAMERIC ENZYME WITH DNA EFFECTOR MOLECULES.
J.Biol.Chem., 290, 2015
5DZM
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HIV-1 Reverse Transcriptase RH domain
分子名称: Ribonuclease H
著者Pedersen, L.C, London, R.E, Gabel, S.A, Zheng, X.H.
登録日2015-09-25
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Unfolding the HIV-1 reverse transcriptase RNase H domain - how to lose a molecular tug-of-war.
Nucleic Acids Res., 44, 2016
4XDS
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Deoxyguanosinetriphosphate Triphosphohydrolase from Escherichia coli with Nickel
分子名称: Deoxyguanosinetriphosphate triphosphohydrolase, NICKEL (II) ION, SULFATE ION
著者Singh, D, Gawel, D, Itsko, M, Krahn, J.M, London, R.E, Schaaper, R.M.
登録日2014-12-19
公開日2015-02-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.354 Å)
主引用文献Structure of Escherichia coli dGTP Triphosphohydrolase: A HEXAMERIC ENZYME WITH DNA EFFECTOR MOLECULES.
J.Biol.Chem., 290, 2015
5E6Q
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Importin alpha binding to XRCC1 NLS peptide
分子名称: CHLORIDE ION, DNA repair protein XRCC1 NLS peptide, GLYCEROL, ...
著者Pedersen, L.C, Kirby, T.W, Gassman, N.R, Smith, C.E, Gabel, S.A, Sobhany, M, Wilson, S.H, London, R.E.
登録日2015-10-10
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.305 Å)
主引用文献Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS.
Sci Rep, 5, 2015
3LQC
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X-ray crystal structure of oxidized XRCC1 bound to DNA pol beta Palm thumb domain
分子名称: CARBONATE ION, DNA polymerase beta, DNA repair protein XRCC1, ...
著者Cuneo, M.J, Krahn, J.M, London, R.E.
登録日2010-02-09
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.349 Å)
主引用文献Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MQ1
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Crystal Structure of Dust Mite Allergen Der p 5
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Mite allergen Der p 5, ...
著者Mueller, G.A, Gosavi, R.A, Krahn, J.M, Edwards, L.L, Cuneo, M.J, Glesner, J, Pomes, A, Chapman, M.D, London, R.E, Pedersen, L.C.
登録日2010-04-27
公開日2010-06-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Der p 5 crystal structure provides insight into the group 5 dust mite allergens.
J.Biol.Chem., 285, 2010
3OB4
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MBP-fusion protein of the major peanut allergen Ara h 2
分子名称: CHLORIDE ION, Maltose ABC transporter periplasmic protein,Arah 2, SULFATE ION, ...
著者Mueller, G.A, Gosavi, R.A, Moon, A.F, London, R.E, Pedersen, L.C.
登録日2010-08-06
公開日2011-02-02
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.706 Å)
主引用文献Ara h 2: crystal structure and IgE binding distinguish two subpopulations of peanut allergic patients by epitope diversity.
Allergy, 66, 2011
6D7N
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Crystal structure of the W357R/W399R Importin alpha mutant
分子名称: 1,2-ETHANEDIOL, Peroxidase,Importin subunit alpha-1
著者Pedersen, L.C, London, R.E, Gabel, S.A.
登録日2018-04-25
公開日2019-03-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Variations in nuclear localization strategies among pol X family enzymes.
Traffic, 2018
6D7M
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Crystal structure of the W184R/W231R Importin alpha mutant
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Peroxidase,Importin subunit alpha-1, ...
著者Pedersen, L.C, London, R.E, Gabel, S.A.
登録日2018-04-25
公開日2019-03-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.187 Å)
主引用文献Variations in nuclear localization strategies among pol X family enzymes.
Traffic, 2018
2HTF
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The solution structure of the BRCT domain from human polymerase reveals homology with the TdT BRCT domain
分子名称: DNA polymerase mu
著者DeRose, E.F, Clarkson, M.W, Gilmore, S.A, Ramsden, D.A, Mueller, G.A, London, R.E, Lee, A.L.
登録日2006-07-25
公開日2007-02-27
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of polymerase mu's BRCT Domain reveals an element essential for its role in nonhomologous end joining.
Biochemistry, 46, 2007
2IDO
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Structure of the E. coli Pol III epsilon-Hot proofreading complex
分子名称: 1,2-ETHANEDIOL, DNA polymerase III epsilon subunit, Hot protein, ...
著者Kirby, T.W, Harvey, S, DeRose, E.F, Chalov, S, Chikova, A.K, Perrino, F.W, Schaaper, R.M, London, R.E, Pedersen, L.C.
登録日2006-09-15
公開日2006-11-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the Escherichia coli DNA polymerase III epsilon-HOT proofreading complex.
J.Biol.Chem., 281, 2006

 

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