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PDB: 37 results

4HRF
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BU of 4hrf by Molmil
Atomic structure of DUSP26
Descriptor: Dual specificity protein phosphatase 26
Authors:Lokareddy, R.K, Bhardwaj, A, Cingolani, G.
Deposit date:2012-10-27
Release date:2013-01-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Atomic structure of dual-specificity phosphatase 26, a novel p53 phosphatase.
Biochemistry, 52, 2013
7UXE
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BU of 7uxe by Molmil
Pseudomonas phage E217 small terminase (TerS)
Descriptor: Small terminase
Authors:Lokareddy, R.K, Hou, C.-F.D, Doll, S.G, Li, F, Gillilan, R, Forti, F, Briani, F, Cingolani, G.
Deposit date:2022-05-05
Release date:2022-09-28
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Terminase Subunits from the Pseudomonas-Phage E217.
J.Mol.Biol., 434, 2022
4XZR
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BU of 4xzr by Molmil
Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh1
Descriptor: Importin subunit alpha, Inner nuclear membrane protein SRC1
Authors:Lokareddy, R.K, Cingolani, G.
Deposit date:2015-02-04
Release date:2015-06-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2.
Structure, 23, 2015
4YI0
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BU of 4yi0 by Molmil
Structure of mouse importin a1 bound to Pom121NLS
Descriptor: Importin subunit alpha-1, Nuclear envelope pore membrane protein POM 121
Authors:Lokareddy, R.K, Cingolani, G.
Deposit date:2015-02-27
Release date:2016-01-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.806 Å)
Cite:Mammalian Pom121 and yeast Heh2 share IBB-like NLSs that support targeting to the inner nuclear membrane
To Be Published
3GZ2
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BU of 3gz2 by Molmil
Crystal structure of IpgC in complex with an IpaB peptide
Descriptor: Chaperone protein ipgC, GLYCEROL, IMIDAZOLE, ...
Authors:Lokareddy, R.K, Lunelli, M, Kolbe, M.
Deposit date:2009-04-06
Release date:2010-04-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Combination of two separate binding domains defines stoichiometry between type III secretion system chaperone IpgC and translocator protein IpaB
J.Biol.Chem., 285, 2010
4PVZ
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BU of 4pvz by Molmil
Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh2
Descriptor: Importin subunit alpha, Inner nuclear membrane protein HEH2
Authors:Lokareddy, R.K, Hapsari, A.R, van Rheenen, M, Bhardwaj, A, Veenhoff, L.M, Cingolani, C.
Deposit date:2014-03-18
Release date:2015-08-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2.
Structure, 23, 2015
5JJ3
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BU of 5jj3 by Molmil
Refined Structure of the Mature Virion Conformation of P22 Portal Protein
Descriptor: Portal protein
Authors:Lokareddy, R.K, Sankhala, R.S, Cingolani, G.
Deposit date:2016-04-22
Release date:2017-02-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (7 Å)
Cite:Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation.
Nat Commun, 8, 2017
5JJ1
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Structure of the Immature Procapsid Conformation of P22 Portal Protein
Descriptor: Portal protein
Authors:Lokareddy, R.K, Cingolani, G.
Deposit date:2016-04-22
Release date:2017-02-08
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation.
Nat Commun, 8, 2017
5V5O
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BU of 5v5o by Molmil
Structure of NLS2K of influenza A virus nucleoprotein bound to importin alpha
Descriptor: Importin subunit alpha-1, Nucleoprotein
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2017-03-14
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.243 Å)
Cite:Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms.
Sci Rep, 7, 2017
6W7T
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BU of 6w7t by Molmil
Structure of PaP3 small terminase
Descriptor: small terminase subunit
Authors:Cingolani, G, Lokareddy, R.
Deposit date:2020-03-19
Release date:2020-11-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Biophysical analysis of Pseudomonas-phage PaP3 small terminase suggests a mechanism for sequence-specific DNA-binding by lateral interdigitation.
Nucleic Acids Res., 48, 2020
6VI2
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BU of 6vi2 by Molmil
Structure of the unaligned Fab4
Descriptor: FAB4 heavy chain, FAB4 light chain
Authors:Cingolani, G, Lokareddy, R, Ko, Y.
Deposit date:2020-01-11
Release date:2020-09-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
6VI1
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Structure of Fab4 bound to P22 TerL(1-33)
Descriptor: Synthetic Fab4 heavy chain, Synthetic Fab4 light chain, Terminase, ...
Authors:Cingolani, G, Lokareddy, R, Ko, Y.
Deposit date:2020-01-11
Release date:2020-09-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
6XMI
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BU of 6xmi by Molmil
Structure of Fab4 bound to P22 TerL(1-33)
Descriptor: Fab Heavy chain, Fab Light chain, Terminase, ...
Authors:Cingolani, G, Lokareddy, R, Ko, Y.
Deposit date:2020-06-30
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
7SZ6
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BU of 7sz6 by Molmil
Kinetically trapped Pseudomonas-phage PaP3 portal protein - delta barrel mutant class-3
Descriptor: Portal protein
Authors:Hou, C.-F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-11-25
Release date:2022-03-30
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (6.24 Å)
Cite:Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
7SZ4
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BU of 7sz4 by Molmil
Kinetically trapped Pseudomonas-phage PaP3 portal protein - delta barrel mutant class-2
Descriptor: Portal protein
Authors:Hou, C.-F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-11-25
Release date:2022-03-30
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
7SYA
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BU of 7sya by Molmil
Kinetically trapped Pseudomonas-phage PaP3 portal protein - Full Length
Descriptor: Portal protein
Authors:Hou, C.F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-11-24
Release date:2022-04-20
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
7SXK
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BU of 7sxk by Molmil
Kinetically trapped Pseudomonas-phage PaP3 portal protein - Full Length
Descriptor: Portal protein
Authors:Hou, C.F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-11-23
Release date:2022-04-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
7JOQ
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BU of 7joq by Molmil
Structure of NV1 small terminase
Descriptor: Small Terminase subunit
Authors:Cingolani, G, Lokareddy, R.
Deposit date:2020-08-07
Release date:2020-11-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Biophysical analysis of Pseudomonas-phage PaP3 small terminase suggests a mechanism for sequence-specific DNA-binding by lateral interdigitation.
Nucleic Acids Res., 48, 2020
6RGV
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BU of 6rgv by Molmil
Truncated FljB phase 2 flagellin
Descriptor: Flagellin
Authors:Lunelli, M, Lokareddy, R.K, Kolbe, M.
Deposit date:2019-04-17
Release date:2020-03-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion.
Nat Commun, 11, 2020
4MBB
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BU of 4mbb by Molmil
Cubic crystal form of PIR1 dual specificity phosphatase core
Descriptor: CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2013-08-19
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Biochemistry, 53, 2014
6E3B
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BU of 6e3b by Molmil
STRUCTURE OF Siw14 CATALYTIC CORE
Descriptor: SULFATE ION, Tyrosine-protein phosphatase SIW14
Authors:Florio, T, Lokareddy, R, Cingolani, G.
Deposit date:2018-07-13
Release date:2019-02-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular Architecture of the Inositol Phosphatase Siw14.
Biochemistry, 58, 2019
8DKR
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BU of 8dkr by Molmil
Pseudomonas-phage E217 TerL nuclease domain
Descriptor: Large terminase protein, MAGNESIUM ION
Authors:Cingolani, G, Lokareddy, R, Hou, D.
Deposit date:2022-07-06
Release date:2022-09-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Terminase Subunits from the Pseudomonas-Phage E217.
J.Mol.Biol., 434, 2022
4NYH
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BU of 4nyh by Molmil
Orthorhombic crystal form of pir1 dual specificity phosphatase core
Descriptor: CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2013-12-10
Release date:2014-01-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Biochemistry, 53, 2014
3GZ1
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BU of 3gz1 by Molmil
Crystal structure of IpgC in complex with the chaperone binding region of IpaB
Descriptor: Chaperone protein ipgC, GLYCEROL, Invasin ipaB
Authors:Lunelli, M, Lokareddy, R.K, Zychlinsky, A, Kolbe, M.
Deposit date:2009-04-06
Release date:2009-06-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:IpaB-IpgC interaction defines binding motif for type III secretion translocator
Proc.Natl.Acad.Sci.USA, 106, 2009
5T94
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BU of 5t94 by Molmil
Crystal structure of Kap60 bound to yeast RCC1 (Prp20)
Descriptor: Guanine nucleotide exchange factor SRM1, Importin subunit alpha
Authors:Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G.
Deposit date:2016-09-09
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.631 Å)
Cite:Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017

 

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