5OGC
| Molecular basis of human kinesin-8 function and inhibition | Descriptor: | 4-chloranyl-2-nitro-1-(phenylsulfonyl)benzene, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Locke, J, Joseph, A.P, Topf, M, Moores, C.A. | Deposit date: | 2017-07-12 | Release date: | 2017-10-25 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structural basis of human kinesin-8 function and inhibition. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5OCU
| Molecular basis of human kinesin-8 function and inhibition | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF18A, ... | Authors: | Locke, J, Joseph, A.P, Topf, M, Moores, C.A. | Deposit date: | 2017-07-03 | Release date: | 2017-10-25 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | Structural basis of human kinesin-8 function and inhibition. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5OAM
| Molecular basis of human kinesin-8 function and inhibition | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF18A, ... | Authors: | Locke, J, Joseph, A.P, Topf, M, Moores, C.A. | Deposit date: | 2017-06-23 | Release date: | 2017-10-25 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | Structural basis of human kinesin-8 function and inhibition. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6ZPH
| Kinesin binding protein complexed with Kif15 motor domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, KIF-binding protein, Kinesin-like protein KIF15, ... | Authors: | Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A. | Deposit date: | 2020-07-08 | Release date: | 2020-12-30 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | The mechanism of kinesin inhibition by kinesin-binding protein. Elife, 9, 2020
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6F0L
| S. cerevisiae MCM double hexamer bound to duplex DNA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (62-MER), DNA replication licensing factor MCM2, ... | Authors: | Abid Ali, F, Pye, V.E, Douglas, M.E, Locke, J, Nans, A, Diffley, J.F.X, Costa, A. | Deposit date: | 2017-11-20 | Release date: | 2017-12-06 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (4.77 Å) | Cite: | Cryo-EM structure of a licensed DNA replication origin. Nat Commun, 8, 2017
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7ZPP
| Cryo-EM structure of the MVV CSC intasome at 4.5A resolution | Descriptor: | Integrase, vDNA, non-transferred strand, ... | Authors: | Ballandras-Colas, A, Maskell, D, Pye, V.E, Locke, J, Swuec, S, Kotecha, A, Costa, A, Cherepanov, P. | Deposit date: | 2022-04-28 | Release date: | 2022-05-11 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | A supramolecular assembly mediates lentiviral DNA integration Science, 355, 2017
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6ZPG
| Kinesin binding protein (KBP) | Descriptor: | KIF-binding protein | Authors: | Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A. | Deposit date: | 2020-07-08 | Release date: | 2020-12-30 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | The mechanism of kinesin inhibition by kinesin-binding protein. Elife, 9, 2020
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6ZPI
| Microtubule complexed with Kif15 motor domain. Symmetrised asymmetric unit | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF15, ... | Authors: | Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A. | Deposit date: | 2020-07-08 | Release date: | 2020-12-30 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | The mechanism of kinesin inhibition by kinesin-binding protein. Elife, 9, 2020
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5M0R
| Cryo-EM reconstruction of the maedi-visna virus (MVV) strand transfer complex | Descriptor: | integrase, tDNA, vDNA, ... | Authors: | Pye, V.E, Ballandras-Colas, A, Maskell, D, Locke, J, Kotecha, A, Costa, A, Cherepanov, P. | Deposit date: | 2016-10-05 | Release date: | 2017-01-18 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | A supramolecular assembly mediates lentiviral DNA integration. Science, 355, 2017
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2JOZ
| Solution NMR structure of protein yxeF, Northeast Structural Genomics Consortium target Sr500a | Descriptor: | Hypothetical protein yxeF | Authors: | Wu, Y, Liu, G, Zhang, Q, Bhatnagar, S, Chen, C, Nwosu, C, Xiao, R, Cunningham, K, Locke, J, Ma, L, Swapna, G, Baran, M, Acton, T, Montelione, G, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-04-10 | Release date: | 2007-05-15 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of protein yxeF , Northeast Structural Genomics Consortium target Sr500a To be Published
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6RQC
| Cryo-EM structure of an MCM loading intermediate | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (88-MER), ... | Authors: | Miller, T.C.R, Locke, J, Costa, A. | Deposit date: | 2019-05-15 | Release date: | 2019-11-20 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM. Nature, 575, 2019
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