5ZNG
 
 | | The crystal complex of immune receptor RGA5A_S of Pia from rice (Oryzae sativa) with rice blast (Magnaporthe oryzae) effector protein AVR1-CO39 | | Descriptor: | AVR1-CO39, NBS-LRR type protein | | Authors: | Guo, L.W, Zhang, Y.K, Liu, Q, Ma, M.Q, Liu, J.F, Peng, Y.L. | | Deposit date: | 2018-04-09 | | Release date: | 2018-10-24 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.189 Å) | | Cite: | Specific recognition of two MAX effectors by integrated HMA domains in plant immune receptors involves distinct binding surfaces
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5YOX
 | | HD domain-containing protein YGK1(YGL101W) | | Descriptor: | HD domain-containing protein YGL101W, ZINC ION | | Authors: | Yang, J, Wang, F, Gao, Z, Zhou, K, Liu, Q. | | Deposit date: | 2017-10-31 | | Release date: | 2018-11-21 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | HD domain-containing protein YGK1(YGL101W)
To Be Published
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7X8R
 | | Cryo-EM structure of the Boc5-bound hGLP-1R-Gs complex | | Descriptor: | 2,4-bis(3-methoxy-4-thiophen-2-ylcarbonyloxy-phenyl)-1,3-bis[[4-[(2-methylpropan-2-yl)oxycarbonylamino]phenyl]carbonylamino]cyclobutane-1,3-dicarboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Cong, Z.T, Zhou, Q.T, Li, Y, Chen, L.N, Zhang, Z.C, Liang, A.Y, Liu, Q, Wu, X.Y, Dai, A.T, Xia, T, Wu, W, Zhang, Y, Yang, D.H, Wang, M.W. | | Deposit date: | 2022-03-14 | | Release date: | 2022-06-29 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Structural basis of peptidomimetic agonism revealed by small- molecule GLP-1R agonists Boc5 and WB4-24.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7X8S
 | | Cryo-EM structure of the WB4-24-bound hGLP-1R-Gs complex | | Descriptor: | 2,4-bis(3-methoxy-4-thiophen-2-ylcarbonyloxy-phenyl)-1,3-bis[[4-(2-methylpropanoylamino)phenyl]carbonylamino]cyclobutane-1,3-dicarboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Cong, Z.T, Zhou, Q.T, Li, Y, Chen, L.N, Zhang, Z.C, Liang, A.Y, Liu, Q, Wu, X.Y, Dai, A.T, Xia, T, Wu, W, Zhang, Y, Yang, D.H, Wang, M.W. | | Deposit date: | 2022-03-14 | | Release date: | 2022-06-29 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Structural basis of peptidomimetic agonism revealed by small- molecule GLP-1R agonists Boc5 and WB4-24.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7V7C
 | | CryoEM structure of DDB1-VprBP-Vpr-UNG2(94-313) complex | | Descriptor: | DDB1- and CUL4-associated factor 1, DNA damage-binding protein 1, Protein Vpr, ... | | Authors: | Wang, D, Xu, J, Liu, Q, Xiang, Y. | | Deposit date: | 2021-08-21 | | Release date: | 2022-08-31 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural insights into the HIV-1 Vpr mediated ubiquitination through the Cullin-RING E3 ubiquitin ligase
To Be Published
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7V7B
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7XH0
 | | crystal structure of Csn-PD from Paenibacillus dendritiformis | | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, Chitosanase | | Authors: | Sun, H.H, Cheng, Y.M, Cao, R, Liu, Q, Zhao, L. | | Deposit date: | 2022-04-07 | | Release date: | 2022-06-08 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | crystal structure of Csn-PD from Paenibacillus dendritiformis
To Be Published
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4CMH
 | | Crystal structure of CD38 with a novel CD38-targeting antibody SAR650984 | | Descriptor: | ADP-RIBOSYL CYCLASE 1, HEAVY CHAIN OF SAR650984-FAB FRAGMENT, LIGHT CHAIN OF SAR650984-FAB FRAGMENT | | Authors: | Deckert, J, Wetzel, M.C, Park, P.U, Bartle, L.M, Skaletskaya, A, Goldmacher, V, Vallee, F, ZhouLiu, Q, Ferrari, P, Pouzieux, S, Lahoute, C, Dumontet, C, Plesa, A, Chiron, M, Lejeune, P, Chittenden, T, Blanc, V. | | Deposit date: | 2014-01-15 | | Release date: | 2014-07-16 | | Last modified: | 2018-10-24 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic malignancies.
Clin. Cancer Res., 20, 2014
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