8PMJ
| Vanadate-trapped BSEP in nanodiscs | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Bile salt export pump, ... | Authors: | Liu, H, Irobalieva, R.N, Kowal, J, Ni, D, Nosol, K, Bang-Sorensen, R, Lancien, L, Stahlberg, H, Stieger, B, Locher, K.P. | Deposit date: | 2023-06-28 | Release date: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (2.81 Å) | Cite: | Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP. Nat Commun, 14, 2023
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4MWH
| Crystal structure of scCK2 alpha in complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Casein kinase II subunit alpha, MAGNESIUM ION, ... | Authors: | Liu, H. | Deposit date: | 2013-09-24 | Release date: | 2013-11-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway. Acta Crystallogr.,Sect.D, 70, 2014
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3U06
| Crystal structure of the kinesin-14 NcdG347D | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Liu, H.-L, Pemble IV, C.W, Endow, S.A. | Deposit date: | 2011-09-28 | Release date: | 2012-03-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Neck-motor interactions trigger rotation of the kinesin stalk. Sci Rep, 2, 2012
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5ZVT
| Structure of RNA polymerase complex and genome within a dsRNA virus provides insights into the mechanisms of transcription and assembly | Descriptor: | C-terminus of outer capsid protein VP5, Core protein VP6, MYRISTIC ACID, ... | Authors: | Liu, H, Fang, Q, Cheng, L. | Deposit date: | 2018-05-12 | Release date: | 2018-07-04 | Last modified: | 2018-07-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of RNA polymerase complex and genome within a dsRNA virus provides insights into the mechanisms of transcription and assembly. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5BT1
| histone chaperone Hif1 playing with histone H2A-H2B dimer | Descriptor: | HAT1-interacting factor 1, Histone H2A.1, Histone H2B.1 | Authors: | Liu, H, Zhang, M, Gao, Y, Teng, M, Niu, L. | Deposit date: | 2015-06-02 | Release date: | 2016-10-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Structural Insights into the Association of Hif1 with Histones H2A-H2B Dimer and H3-H4 Tetramer Structure, 24, 2016
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8I4M
| Portal-tail complex structure of the Cyanophage P-SCSP1u | Descriptor: | Adaptor protein(gp22) of the cyanophage P-SCSP1u, Fiber protein(gp 28) of the cyanophage P-SCSP1u, Nozzle protein(gp 23) of the cyanophage P-SCSP1u, ... | Authors: | Liu, H, Dang, S. | Deposit date: | 2023-01-19 | Release date: | 2023-11-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.81 Å) | Cite: | Cryo-EM structure of cyanophage P-SCSP1u offers insights into DNA gating and evolution of T7-like viruses. Nat Commun, 14, 2023
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4JR7
| Crystal structure of scCK2 alpha in complex with GMPPNP | Descriptor: | Casein kinase II subunit alpha, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Liu, H. | Deposit date: | 2013-03-21 | Release date: | 2014-03-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway. Acta Crystallogr.,Sect.D, 70, 2014
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4JQE
| Crystal structure of scCK2 alpha in complex with AMPPN | Descriptor: | Casein kinase II subunit alpha, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Liu, H. | Deposit date: | 2013-03-20 | Release date: | 2014-03-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway. Acta Crystallogr.,Sect.D, 70, 2014
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7EYB
| core proteins | Descriptor: | Internal virion protein gp14, Internal virion protein gp15, Peptidoglycan transglycosylase gp16 | Authors: | Liu, H.R, Chen, W.Y. | Deposit date: | 2021-05-30 | Release date: | 2021-09-22 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural changes in bacteriophage T7 upon receptor-induced genome ejection. Proc.Natl.Acad.Sci.USA, 118, 2021
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7EY9
| tail proteins | Descriptor: | Tail fiber protein, Tail tubular protein gp11, Tail tubular protein gp12 | Authors: | Liu, H.R, Chen, W.Y. | Deposit date: | 2021-05-30 | Release date: | 2021-09-22 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural changes in bacteriophage T7 upon receptor-induced genome ejection. Proc.Natl.Acad.Sci.USA, 118, 2021
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7EY7
| bacteriophage T7 tail complex | Descriptor: | Internal virion protein gp14, Tail fiber protein, Tail tubular protein gp11, ... | Authors: | Liu, H.R, Chen, W.Y. | Deposit date: | 2021-05-30 | Release date: | 2021-09-22 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural changes in bacteriophage T7 upon receptor-induced genome ejection. Proc.Natl.Acad.Sci.USA, 118, 2021
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8PMD
| Nucleotide-bound BSEP in nanodiscs | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Bile salt export pump, MAGNESIUM ION | Authors: | Liu, H, Irobalieva, R.N, Kowal, J, Ni, D, Nosol, K, Bang-Sorensen, R, Lancien, L, Stahlberg, H, Stieger, B, Locher, K.P. | Deposit date: | 2023-06-28 | Release date: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP. Nat Commun, 14, 2023
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6KTR
| Crystal structure of fibroblast growth factor 19 in complex with Fab | Descriptor: | Fibroblast growth factor 19, G1A8-Fab-HC, G1A8-Fab-LC, ... | Authors: | Liu, H, Zheng, S, Hou, X, Liu, X, Lv, X, Li, Y, Li, W, Sui, J. | Deposit date: | 2019-08-28 | Release date: | 2020-07-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.59775758 Å) | Cite: | Novel Abs targeting the N-terminus of fibroblast growth factor 19 inhibit hepatocellular carcinoma growth without bile-acid-related side-effects. Cancer Sci., 111, 2020
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5Y4M
| Discoidin domain of human CASPR2 | Descriptor: | 1,2-ETHANEDIOL, human CASPR2 Disc domain | Authors: | Liu, H, Xu, F, Zhang, J, Liang, W. | Deposit date: | 2017-08-04 | Release date: | 2018-08-08 | Last modified: | 2019-02-20 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Structural mapping of hot spots within human CASPR2 discoidin domain for autoantibody recognition. J. Autoimmun., 96, 2019
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7EY6
| The portal protein (GP8) of bacteriophage T7 | Descriptor: | Portal protein | Authors: | Liu, H.R, Chen, W.Y. | Deposit date: | 2021-05-30 | Release date: | 2021-09-22 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural changes in bacteriophage T7 upon receptor-induced genome ejection. Proc.Natl.Acad.Sci.USA, 118, 2021
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7EY8
| portal | Descriptor: | Portal protein | Authors: | Liu, H.R, Chen, W.Y. | Deposit date: | 2021-05-30 | Release date: | 2021-09-22 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural changes in bacteriophage T7 upon receptor-induced genome ejection. Proc.Natl.Acad.Sci.USA, 118, 2021
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3NTI
| Crystal structure of Tudor and Aubergine [R15(me2s)] complex | Descriptor: | Maternal protein tudor, peptide from Aubergine | Authors: | Liu, H.P, Huang, Y, Li, Z.Z, Gong, W.M, Xu, R.M. | Deposit date: | 2010-07-05 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for methylarginine-dependent recognition of Aubergine by Tudor Genes Dev., 24, 2010
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3NTK
| Crystal structure of Tudor | Descriptor: | Maternal protein tudor | Authors: | Liu, H.P, Huang, Y, Li, Z.Z, Gong, W.M, Xu, R.M. | Deposit date: | 2010-07-05 | Release date: | 2010-09-15 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for methylarginine-dependent recognition of Aubergine by Tudor Genes Dev., 24, 2010
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2O26
| Structure of a class III RTK signaling assembly | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Kit ligand, Mast/stem cell growth factor receptor, ... | Authors: | Liu, H, Chen, X, Focia, P.J, He, X. | Deposit date: | 2006-11-29 | Release date: | 2007-03-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for stem cell factor-KIT signaling and activation of class III receptor tyrosine kinases. Embo J., 26, 2007
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3NTH
| Crystal structure of Tudor and Aubergine [R13(me2s)] complex | Descriptor: | Maternal protein tudor, peptide from Aubergine | Authors: | Liu, H.P, Huang, Y, Li, Z.Z, Gong, W.M, Xu, R.M. | Deposit date: | 2010-07-05 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for methylarginine-dependent recognition of Aubergine by Tudor Genes Dev., 24, 2010
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5ZVS
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4QU2
| The structure of JMJD7 with alpha-KG | Descriptor: | 2-OXOGLUTARIC ACID, JmjC domain-containing protein 7, NICKEL (II) ION | Authors: | Liu, H.L, Wang, C, Zhang, G.Y. | Deposit date: | 2014-07-10 | Release date: | 2015-07-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structure of JMJD7 with alpha-KG To be Published
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3P40
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3P3Y
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6DKU
| Crystal structure of Myotis VP35 mutant of interferon inhibitory domain | Descriptor: | VP35 | Authors: | Liu, H, Ginell, G.M, Keefe, L.J, Leung, D.W, Amarasinghe, G.K. | Deposit date: | 2018-05-30 | Release date: | 2018-07-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes. Cell Rep, 24, 2018
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