8H9J
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![BU of 8h9j by Molmil](/molmil-images/mine/8h9j) | Human ATP synthase state2 subregion 3 | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ... | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | Deposit date: | 2022-10-25 | Release date: | 2023-05-31 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9T
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![BU of 8h9t by Molmil](/molmil-images/mine/8h9t) | Human ATP synthase state 2 (combined) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | Deposit date: | 2022-10-25 | Release date: | 2023-05-31 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9F
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![BU of 8h9f by Molmil](/molmil-images/mine/8h9f) | Human ATP synthase state 1 subregion 3 | Descriptor: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ATP synthase F(0) complex subunit B1, mitochondrial, ... | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | Deposit date: | 2022-10-25 | Release date: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9I
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![BU of 8h9i by Molmil](/molmil-images/mine/8h9i) | Human ATP synthase F1 domain, state2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit O, ... | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | Deposit date: | 2022-10-25 | Release date: | 2023-05-31 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9R
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![BU of 8h9r by Molmil](/molmil-images/mine/8h9r) | Human ATP synthase state 3b subregion 2 | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase subunit d, ... | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | Deposit date: | 2022-10-25 | Release date: | 2023-05-31 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.97 Å) | Cite: | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9P
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![BU of 8h9p by Molmil](/molmil-images/mine/8h9p) | Human ATP synthase F1 domain, state 3b | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit O, ... | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | Deposit date: | 2022-10-25 | Release date: | 2023-05-31 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9N
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![BU of 8h9n by Molmil](/molmil-images/mine/8h9n) | Human ATP synthase state 3a subregion 2 | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase subunit d, ... | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | Deposit date: | 2022-10-25 | Release date: | 2023-05-31 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9K
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![BU of 8h9k by Molmil](/molmil-images/mine/8h9k) | Human ATP synthase state 2 subregion 2 | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase subunit d, ... | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | Deposit date: | 2022-10-25 | Release date: | 2023-05-31 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9L
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![BU of 8h9l by Molmil](/molmil-images/mine/8h9l) | Human ATP synthase F1 domain, state 3a | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit O, ... | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | Deposit date: | 2022-10-25 | Release date: | 2023-05-31 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.61 Å) | Cite: | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9E
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![BU of 8h9e by Molmil](/molmil-images/mine/8h9e) | Human ATP synthase F1 domain, state 1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit O, ... | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | Deposit date: | 2022-10-25 | Release date: | 2023-05-31 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9G
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![BU of 8h9g by Molmil](/molmil-images/mine/8h9g) | Human ATP synthase state 1 subregion 2 | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase subunit d, ... | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | Deposit date: | 2022-10-25 | Release date: | 2023-05-31 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8J0T
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![BU of 8j0t by Molmil](/molmil-images/mine/8j0t) | Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in the apo-form | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H. | Deposit date: | 2023-04-11 | Release date: | 2024-05-22 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587. Nature, 631, 2024
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8J0S
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![BU of 8j0s by Molmil](/molmil-images/mine/8j0s) | Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in complex with bedaquiline(BDQ) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H. | Deposit date: | 2023-04-11 | Release date: | 2024-05-22 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (2.58 Å) | Cite: | Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587. Nature, 631, 2024
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8J57
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![BU of 8j57 by Molmil](/molmil-images/mine/8j57) | Cryo-EM structure of Mycobacterium tuberculosis ATP synthase Fo in complex with bedaquiline(BDQ) | Descriptor: | ATP synthase subunit a, ATP synthase subunit c, Bedaquiline | Authors: | Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H. | Deposit date: | 2023-04-21 | Release date: | 2024-05-01 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587. Nature, 631, 2024
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8J58
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![BU of 8j58 by Molmil](/molmil-images/mine/8j58) | Cryo-EM structure of Mycobacterium tuberculosis ATP synthase Fo in the apo-form | Descriptor: | ATP synthase subunit a, ATP synthase subunit c | Authors: | Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H. | Deposit date: | 2023-04-21 | Release date: | 2024-05-01 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587. Nature, 631, 2024
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5W81
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![BU of 5w81 by Molmil](/molmil-images/mine/5w81) | Phosphorylated, ATP-bound structure of zebrafish cystic fibrosis transmembrane conductance regulator (CFTR) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | Authors: | Zhang, Z, Liu, F, Chen, J. | Deposit date: | 2017-06-21 | Release date: | 2017-07-19 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Conformational Changes of CFTR upon Phosphorylation and ATP Binding. Cell, 170, 2017
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7WNX
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![BU of 7wnx by Molmil](/molmil-images/mine/7wnx) | Cryo-EM structure of Mycobacterium smegmatis MmpL3 complexed with ST004 in lipid nanodiscs | Descriptor: | N-[2-(2-adamantylamino)ethyl]-1-[2,4-bis(fluoranyl)phenyl]-5-(4-chlorophenyl)-4-methyl-pyrazole-3-carboxamide, Trehalose monomycolate exporter MmpL3 | Authors: | Zhang, B, Hu, T, Yang, X, Liu, F, Rao, Z. | Deposit date: | 2022-01-20 | Release date: | 2022-08-03 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Structure-based design of anti-mycobacterial drug leads that target the mycolic acid transporter MmpL3. Structure, 30, 2022
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7D94
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![BU of 7d94 by Molmil](/molmil-images/mine/7d94) | Crystal Structure of the Na+,K+-ATPase in the E2P state with bound one Mg2+ and one Rb+ in the presence of bufalin | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kanai, R, Cornelius, F, Ogawa, H, Motoyama, K, Vilsen, B, Toyoshima, C. | Deposit date: | 2020-10-12 | Release date: | 2021-01-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state. Proc.Natl.Acad.Sci.USA, 118, 2021
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7DDF
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![BU of 7ddf by Molmil](/molmil-images/mine/7ddf) | Crystal structures of Na+,K+-ATPase in complex with beryllium fluoride | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ogawa, H, Cornelius, F, Kanai, R, Motoyama, K, Vilsen, B, Toyoshima, C. | Deposit date: | 2020-10-29 | Release date: | 2021-01-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (4.62 Å) | Cite: | Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state. Proc.Natl.Acad.Sci.USA, 118, 2021
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3WGV
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![BU of 3wgv by Molmil](/molmil-images/mine/3wgv) | Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state with oligomycin | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Kanai, R, Ogawa, H, Vilsen, B, Cornelius, F, Toyoshima, C. | Deposit date: | 2013-08-09 | Release date: | 2013-10-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a Na1-bound Na1,K1-ATPase preceding the E1P state Nature, 502, 2013
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8JFZ
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![BU of 8jfz by Molmil](/molmil-images/mine/8jfz) | Cryo-EM structure of Na+,K+-ATPase in the E1.Mg2+ state. | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kanai, R, Vilsen, B, Cornelius, F, Toyoshima, C. | Deposit date: | 2023-05-19 | Release date: | 2023-08-09 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Crystal structures of Na + ,K + -ATPase reveal the mechanism that converts the K + -bound form to Na + -bound form and opens and closes the cytoplasmic gate. Febs Lett., 597, 2023
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8JBM
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![BU of 8jbm by Molmil](/molmil-images/mine/8jbm) | Crystal structure of Na+,K+-ATPase in the E1.Mn2+ state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kanai, R, Vilsen, B, Cornelius, F, Toyoshima, C. | Deposit date: | 2023-05-09 | Release date: | 2023-08-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structures of Na + ,K + -ATPase reveal the mechanism that converts the K + -bound form to Na + -bound form and opens and closes the cytoplasmic gate. Febs Lett., 597, 2023
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8JBL
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![BU of 8jbl by Molmil](/molmil-images/mine/8jbl) | Crystal structure of Na+,K+-ATPase in the E1.Mg2+ state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kanai, R, Vilsen, B, Cornelius, F, Toyoshima, C. | Deposit date: | 2023-05-09 | Release date: | 2023-08-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structures of Na + ,K + -ATPase reveal the mechanism that converts the K + -bound form to Na + -bound form and opens and closes the cytoplasmic gate. Febs Lett., 597, 2023
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8JBK
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![BU of 8jbk by Molmil](/molmil-images/mine/8jbk) | Crystal structure of Na+,K+-ATPase in the E1.3Na+ state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kanai, R, Vilsen, B, Cornelius, F, Toyoshima, C. | Deposit date: | 2023-05-09 | Release date: | 2023-08-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structures of Na + ,K + -ATPase reveal the mechanism that converts the K + -bound form to Na + -bound form and opens and closes the cytoplasmic gate. Febs Lett., 597, 2023
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3WGU
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![BU of 3wgu by Molmil](/molmil-images/mine/3wgu) | Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state without oligomycin | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Kanai, R, Ogawa, H, Vilsen, B, Cornelius, F, Toyoshima, C. | Deposit date: | 2013-08-09 | Release date: | 2013-10-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a Na1-bound Na1,K1-ATPase preceding the E1P state Nature, 502, 2013
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