2VJN
| Formyl-CoA transferase mutant variant G260A | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FORMYL-COENZYME A TRANSFERASE | Authors: | Berthold, C.L, Toyota, C.G, Richards, N.G.J, Lindqvist, Y. | Deposit date: | 2007-12-11 | Release date: | 2007-12-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Reinvestigation of the Catalytic Mechanism of Formyl-Coa Transferase, a Class III Coa-Transferase. J.Biol.Chem., 283, 2008
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2WG8
| Structure of Oryza Sativa (Rice) PLA2, orthorhombic crystal form | Descriptor: | CALCIUM ION, PUTATIVE PHOSPHOLIPASE A2, SODIUM ION | Authors: | Guy, J.E, Stahl, U, Lindqvist, Y. | Deposit date: | 2009-04-16 | Release date: | 2009-06-02 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of a Class Xib Phospholipase A2 (Pla2): Rice (Oryza Sativa) Isoform-2 Pla2 and an Octanoate Complex. J.Biol.Chem., 284, 2009
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2WG7
| Structure of Oryza Sativa (Rice) PLA2 | Descriptor: | CALCIUM ION, PUTATIVE PHOSPHOLIPASE A2, SODIUM ION | Authors: | Guy, J.E, Stahl, U, Lindqvist, Y. | Deposit date: | 2009-04-16 | Release date: | 2009-06-02 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of a Class Xib Phospholipase A2 (Pla2): Rice (Oryza Sativa) Isoform-2 Pla2 and an Octanoate Complex. J.Biol.Chem., 284, 2009
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2WG9
| Structure of Oryza Sativa (Rice) PLA2, complex with octanoic acid | Descriptor: | CALCIUM ION, OCTANOIC ACID (CAPRYLIC ACID), PUTATIVE PHOSPHOLIPASE A2, ... | Authors: | Guy, J.E, Stahl, U, Lindqvist, Y. | Deposit date: | 2009-04-16 | Release date: | 2009-06-02 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of a Class Xib Phospholipase A2 (Pla2): Rice (Oryza Sativa) Isoform-2 Pla2 and an Octanoate Complex. J.Biol.Chem., 284, 2009
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6T6P
| Crystal structure of Klebsiella pneumoniae FabG2(NADH-dependent) at 1.57 A resolution | Descriptor: | 3-oxoacyl-[acyl-carrier protein] reductase, GLYCEROL, PHOSPHATE ION | Authors: | Vella, P, Schnell, R, Lindqvist, Y, Schneider, G. | Deposit date: | 2019-10-18 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens. Bioorg.Med.Chem., 30, 2021
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1H7X
| Dihydropyrimidine dehydrogenase (DPD) from pig, ternary complex of a mutant enzyme (C671A), NADPH and 5-fluorouracil | Descriptor: | 5-FLUOROURACIL, DIHYDROPYRIMIDINE DEHYDROGENASE, FLAVIN MONONUCLEOTIDE, ... | Authors: | Dobritzsch, D, Schneider, G, Schnackerz, K.D, Lindqvist, Y. | Deposit date: | 2001-01-19 | Release date: | 2001-02-23 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal Structure of Dihydropyrimidine Dehydrogenase, a Major Determinant of the Pharmacokinetics of the Anti-Cancer Drug 5-Fluorouracil Embo J., 20, 2001
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1DAG
| DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID AND 5'-ADENOSYL-METHYLENE-TRIPHOSPHATE | Descriptor: | 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID, DETHIOBIOTIN SYNTHETASE, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | Authors: | Huang, W, Jia, J, Schneider, G, Lindqvist, Y. | Deposit date: | 1995-05-08 | Release date: | 1996-06-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate. Biochemistry, 34, 1995
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1DAI
| DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID | Descriptor: | 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID, DETHIOBIOTIN SYNTHETASE | Authors: | Huang, W, Jia, J, Schneider, G, Lindqvist, Y. | Deposit date: | 1995-05-08 | Release date: | 1996-06-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate. Biochemistry, 34, 1995
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1DAH
| DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 7,8-DIAMINO-NONANOIC ACID, 5'-ADENOSYL-METHYLENE-TRIPHOSPHATE, AND MANGANESE | Descriptor: | 7,8-DIAMINO-NONANOIC ACID, DETHIOBIOTIN SYNTHETASE, MANGANESE (II) ION, ... | Authors: | Huang, W, Jia, J, Schneider, G, Lindqvist, Y. | Deposit date: | 1995-05-08 | Release date: | 1996-06-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate. Biochemistry, 34, 1995
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1R7H
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1DAF
| DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID, ADP, AND CALCIUM | Descriptor: | 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | Authors: | Huang, W, Jia, J, Schneider, G, Lindqvist, Y. | Deposit date: | 1995-05-08 | Release date: | 1996-06-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate. Biochemistry, 34, 1995
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1DAE
| DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 3-(1-AMINOETHYL) NONANEDIOIC ACID | Descriptor: | 3-(1-AMINOETHYL)NONANEDIOIC ACID, DETHIOBIOTIN SYNTHETASE | Authors: | Huang, W, Jia, J, Schneider, G, Lindqvist, Y. | Deposit date: | 1995-05-08 | Release date: | 1996-06-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate. Biochemistry, 34, 1995
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1R9J
| Transketolase from Leishmania mexicana | Descriptor: | CALCIUM ION, THIAMINE DIPHOSPHATE, transketolase | Authors: | Veitch, N.J, Mauger, D.A, Cazzulo, J.J, Lindqvist, Y, Barrett, M.P. | Deposit date: | 2003-10-30 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Transketolase from Leishmania mexicana has a dual subcellular localization. Biochem.J., 382, 2004
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1R1Z
| The Crystal structure of the Carbohydrate recognition domain of the glycoprotein sorting receptor p58/ERGIC-53 reveals a novel metal binding site and conformational changes associated with calcium ion binding | Descriptor: | CALCIUM ION, ERGIC-53 protein | Authors: | Velloso, L.M, Svensson, K, Pettersson, R.F, Lindqvist, Y. | Deposit date: | 2003-09-25 | Release date: | 2003-12-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Crystal Structure of the Carbohydrate-recognition Domain of the Glycoprotein Sorting Receptor p58/ERGIC-53 Reveals an Unpredicted Metal-binding Site and Conformational Changes Associated with Calcium Ion Binding. J.Mol.Biol., 334, 2003
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1FF9
| APO SACCHAROPINE REDUCTASE | Descriptor: | SACCHAROPINE REDUCTASE, SULFATE ION | Authors: | Johansson, E, Steffens, J.J, Lindqvist, Y, Schneider, G. | Deposit date: | 2000-07-25 | Release date: | 2000-11-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of saccharopine reductase from Magnaporthe grisea, an enzyme of the alpha-aminoadipate pathway of lysine biosynthesis. Structure Fold.Des., 8, 2000
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1FOH
| PHENOL HYDROXYLASE FROM TRICHOSPORON CUTANEUM | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PHENOL, PHENOL HYDROXYLASE | Authors: | Enroth, C, Neujahr, H, Schneider, G, Lindqvist, Y. | Deposit date: | 1998-03-26 | Release date: | 1998-06-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The crystal structure of phenol hydroxylase in complex with FAD and phenol provides evidence for a concerted conformational change in the enzyme and its cofactor during catalysis. Structure, 6, 1998
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1DAD
| DETHIOBIOTIN SYNTHETASE COMPLEXED WITH ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DETHIOBIOTIN SYNTHETASE | Authors: | Huang, W, Jia, J, Schneider, G, Lindqvist, Y. | Deposit date: | 1995-05-08 | Release date: | 1996-06-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate. Biochemistry, 34, 1995
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1E5L
| Apo saccharopine reductase from Magnaporthe grisea | Descriptor: | SACCHAROPINE REDUCTASE | Authors: | Johansson, E, Steffens, J.J, Lindqvist, Y, Schneider, G. | Deposit date: | 2000-07-27 | Release date: | 2000-11-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of Saccharopine Reductase from Magnaporthe Grisea, an Enzyme of the Alpha-Aminoadipate Pathway of Lysine Biosynthesis Structure, 8, 2000
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6T77
| Crystal structure of Klebsiella pneumoniae FabG(NADPH-dependent) NADP-complex at 1.75 A resolution | Descriptor: | 3-oxoacyl-ACP reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Vella, P, Schnell, R, Lindqvist, Y, Schneider, G. | Deposit date: | 2019-10-21 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens. Bioorg.Med.Chem., 30, 2021
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1E5M
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1E5Q
| Ternary complex of saccharopine reductase from Magnaporthe grisea, NADPH and saccharopine | Descriptor: | N-(5-AMINO-5-CARBOXYPENTYL)GLUTAMIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Saccharopine dehydrogenase [NADP(+), ... | Authors: | Johansson, E, Steffens, J.J, Lindqvist, Y, Schneider, G. | Deposit date: | 2000-07-28 | Release date: | 2000-12-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of Saccharopine Reductase from Magnaporthe Grisea, an Enzyme of the Alpha-Aminoadipate Pathway of Lysine Biosynthesis Structure, 8, 2000
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1H7W
| Dihydropyrimidine dehydrogenase (DPD) from pig | Descriptor: | DIHYDROPYRIMIDINE DEHYDROGENASE, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Dobritzsch, D, Schneider, G, Schnackerz, K.D, Lindqvist, Y. | Deposit date: | 2001-01-19 | Release date: | 2001-02-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracil. EMBO J., 20, 2001
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1DAK
| DETHIOBIOTIN SYNTHETASE FROM ESCHERICHIA COLI, COMPLEX REACTION INTERMEDIATE ADP AND MIXED ANHYDRIDE | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DETHIOBIOTIN SYNTHETASE, MAGNESIUM ION, ... | Authors: | Kaeck, H, Gibson, K.J, Lindqvist, Y, Schneider, G. | Deposit date: | 1998-03-31 | Release date: | 1999-04-06 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Snapshot of a phosphorylated substrate intermediate by kinetic crystallography. Proc.Natl.Acad.Sci.USA, 95, 1998
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1DTS
| CRYSTAL STRUCTURE OF AN ATP DEPENDENT CARBOXYLASE, DETHIOBIOTIN SYNTHASE, AT 1.65 ANGSTROMS RESOLUTION | Descriptor: | DETHIOBIOTIN SYNTHETASE | Authors: | Huang, W, Lindqvist, Y, Schneider, G. | Deposit date: | 1995-03-28 | Release date: | 1995-04-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of an ATP-dependent carboxylase, dethiobiotin synthetase, at 1.65 A resolution. Structure, 2, 1994
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4A7Z
| Complex of bifunctional aldos-2-ulose dehydratase with the reaction intermediate ascopyrone M | Descriptor: | ALDOS-2-ULOSE DEHYDRATASE, Ascopyrone M, MAGNESIUM ION, ... | Authors: | Claesson, M, Lindqvist, Y, Madrid, S, Sandalova, T, Fiskesund, R, Yu, S, Schneider, G. | Deposit date: | 2011-11-15 | Release date: | 2012-03-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of Bifunctional Aldos-2-Ulose Dehydratase/Isomerase from Phanerochaete Chrysosporium with the Reaction Intermediate Ascopyrone M. J.Mol.Biol., 417, 2012
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