1H7W
Dihydropyrimidine dehydrogenase (DPD) from pig
Summary for 1H7W
Entry DOI | 10.2210/pdb1h7w/pdb |
Related | 1H7X |
Descriptor | DIHYDROPYRIMIDINE DEHYDROGENASE, IRON/SULFUR CLUSTER, FLAVIN MONONUCLEOTIDE, ... (5 entities in total) |
Functional Keywords | electron transfer, flavin, iron-sulfur clusters, pyrimidine catabolism, oxidoreductase |
Biological source | SUS SCROFA (WILD BOAR) |
Total number of polymer chains | 4 |
Total formula weight | 457007.19 |
Authors | Dobritzsch, D.,Schneider, G.,Schnackerz, K.D.,Lindqvist, Y. (deposition date: 2001-01-19, release date: 2001-02-23, Last modification date: 2024-05-08) |
Primary citation | Dobritzsch, D.,Schneider, G.,Schnackerz, K.D.,Lindqvist, Y. Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracil. EMBO J., 20:650-660, 2001 Cited by PubMed: 11179210DOI: 10.1093/emboj/20.4.650 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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