3QX3
 
 | | Human topoisomerase IIbeta in complex with DNA and etoposide | | Descriptor: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ... | | Authors: | Wu, C.C, Li, T.K, Farh, L, Lin, L.Y, Lin, T.S, Yu, Y.J, Yen, T.J, Chiang, C.W, Chan, N.L. | | Deposit date: | 2011-03-01 | | Release date: | 2011-07-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.162 Å) | | Cite: | Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide
Science, 333, 2011
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4J12
 | | monomeric Fc | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, human Fc fragment | | Authors: | Ishino, T, Wang, M, Mosyak, L, Tam, A, Duan, W, Svenson, K, Joyce, A, O'Hara, D, Lin, L, Somers, W, Kriz, R. | | Deposit date: | 2013-01-31 | | Release date: | 2013-05-01 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Engineering a Monomeric Fc Domain Modality by N-Glycosylation for the Half-life Extension of Biotherapeutics.
J.Biol.Chem., 288, 2013
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6CW0
 | | Crystal structure of Cryptosporidium parvum bromodomain cgd2_2690 | | Descriptor: | 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, Cgd2_2690 protein, GLYCEROL, ... | | Authors: | Dong, A, Lin, L, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Structural Genomics Consortium (SGC) | | Deposit date: | 2018-03-29 | | Release date: | 2018-04-18 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.38 Å) | | Cite: | Crystal structure of Cryptosporidium parvum bromodomain cgd2_2690
to be published
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8TO2
 | | Bottom cylinder of high-resolution phycobilisome quenched by OCP (local refinement) | | Descriptor: | Allophycocyanin alpha chain, Allophycocyanin beta chain, Allophycocyanin subunit alpha-B, ... | | Authors: | Sauer, P.V, Sutter, M, Cupellini, L. | | Deposit date: | 2023-08-02 | | Release date: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (2 Å) | | Cite: | Structural and quantum chemical basis for OCP-mediated quenching of phycobilisomes.
Sci Adv, 10, 2024
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1F2H
 | | SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF THE TNFR1 ASSOCIATED PROTEIN, TRADD. | | Descriptor: | TUMOR NECROSIS FACTOR RECEPTOR TYPE 1 ASSOCIATED DEATH DOMAIN PROTEIN | | Authors: | Tsao, D, McDonaugh, T, Malakian, K, Xu, G.-Y, Telliez, J.-B, Hsu, H, Lin, L.-L. | | Deposit date: | 2000-05-24 | | Release date: | 2001-05-30 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of N-TRADD and characterization of the interaction of N-TRADD and C-TRAF2, a key step in the TNFR1 signaling pathway.
Mol.Cell, 5, 2000
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2PBF
 | | Crystal structure of a putative protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase (PCMT) from Plasmodium falciparum in complex with S-adenosyl-L-homocysteine | | Descriptor: | Protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Wernimont, A.K, Hassanali, A, Lin, L, Lew, J, Zhao, Y, Ravichandran, M, Wasney, G, Vedadi, M, Kozieradzki, I, Bochkarev, A, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Qiu, W, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-03-28 | | Release date: | 2007-04-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of a putative protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase (PCMT) from Plasmodium falciparum in complex with S-adenosyl-L-homocysteine
To be Published
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8TRO
 | | Rod from high-resolution phycobilisome quenched by OCP (local refinement) | | Descriptor: | C-phycocyanin alpha subunit, C-phycocyanin beta subunit, PHYCOCYANOBILIN, ... | | Authors: | Sauer, P.V, Sutter, M, Cupellini, L. | | Deposit date: | 2023-08-09 | | Release date: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (1.9 Å) | | Cite: | Structural and quantum chemical basis for OCP-mediated quenching of phycobilisomes.
Sci Adv, 10, 2024
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8TO5
 | | Central rod disk in C1 symmetry of high-resolution phycobilisome quenched by OCP (local refinement) | | Descriptor: | C-phycocyanin alpha subunit, C-phycocyanin beta subunit, PHYCOCYANOBILIN, ... | | Authors: | Sauer, P.V, Sutter, M, Cupellini, L. | | Deposit date: | 2023-08-02 | | Release date: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (1.87 Å) | | Cite: | Structural and quantum chemical basis for OCP-mediated quenching of phycobilisomes.
Sci Adv, 10, 2024
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3W9D
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3W9E
 | | Structure of Human Monoclonal Antibody E317 Fab Complex with HSV-2 gD | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ... | | Authors: | Lee, C.C, Lin, L.L, Wang, A.H.J. | | Deposit date: | 2013-04-03 | | Release date: | 2013-10-02 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for the antibody neutralization of herpes simplex virus
Acta Crystallogr.,Sect.D, 69, 2013
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3WHM
 | | Structure of Hemoglobin Complex with 18-crown-6 | | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | | Authors: | Lee, C.C, Lin, L.L, Wang, A.H.J. | | Deposit date: | 2013-08-27 | | Release date: | 2014-10-15 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crowning proteins: modulating the protein surface properties using crown ethers.
Angew.Chem.Int.Ed.Engl., 53, 2014
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3G7N
 | | Crystal Structure of a Triacylglycerol Lipase from Penicillium Expansum at 1.3 | | Descriptor: | DI(HYDROXYETHYL)ETHER, Lipase, PENTAETHYLENE GLYCOL, ... | | Authors: | Bian, C.B, Yuan, C, Chen, L.Q, Edward, J.M, Lin, L, Jiang, L.G, Huang, Z.X, Huang, M.D. | | Deposit date: | 2009-02-10 | | Release date: | 2010-02-23 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Crystal structure of a triacylglycerol lipase from Penicillium expansum at 1.3 A determined by sulfur SAD
Proteins, 78, 2010
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3ES5
 | | Crystal Structure of Partitivirus (PsV-F) | | Descriptor: | Putative capsid protein | | Authors: | Pan, J, Dong, L, Lin, L, Ochoa, W.F, Sinkovits, R.S, Havens, W.M, Nibert, M.L, Baker, T.S, Ghabrial, S.A, Tao, Y.J. | | Deposit date: | 2008-10-03 | | Release date: | 2009-03-10 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Atomic structure reveals the unique capsid organization of a dsRNA virus.
Proc.Natl.Acad.Sci.USA, 106, 2009
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8IMS
 | | Crystal structure of TRAF7 coiled-coil domain | | Descriptor: | E3 ubiquitin-protein ligase TRAF7 | | Authors: | Hu, R, Lin, L, Lu, Q. | | Deposit date: | 2023-03-07 | | Release date: | 2024-01-24 | | Last modified: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | The structure of TRAF7 coiled-coil trimer provides insight into its function in zebrafish embryonic development.
J Mol Cell Biol, 16, 2024
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1F7T
 | | HOLO-(ACYL CARRIER PROTEIN) SYNTHASE AT 1.8A | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, GLYCEROL, ... | | Authors: | Parris, K.D, Lin, L, Tam, A, Mathew, R, Hixon, J, Stahl, M, Fritz, C.C, Seehra, J, Somers, W.S. | | Deposit date: | 2000-06-27 | | Release date: | 2001-06-27 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites.
Structure Fold.Des., 8, 2000
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1F80
 | | HOLO-(ACYL CARRIER PROTEIN) SYNTHASE IN COMPLEX WITH HOLO-(ACYL CARRIER PROTEIN) | | Descriptor: | ACYL CARRIER PROTEIN, HOLO-(ACYL CARRIER PROTEIN) SYNTHASE, SODIUM ION | | Authors: | Parris, K.D, Lin, L, Tam, A, Mathew, R, Hixon, J, Stahl, M, Fritz, C.C, Seehra, J, Somers, W.S. | | Deposit date: | 2000-06-28 | | Release date: | 2001-06-28 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites.
Structure Fold.Des., 8, 2000
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2N3D
 | | Atomic structure of the cytoskeletal bactofilin BacA revealed by solid-state NMR | | Descriptor: | Bactofilin A | | Authors: | Shi, C, Fricke, P, Lin, L, Chevelkov, V, Wegstroth, M, Giller, K, Becker, S, Thanbichler, M, Lange, A. | | Deposit date: | 2015-05-29 | | Release date: | 2015-12-16 | | Last modified: | 2024-05-15 | | Method: | SOLID-STATE NMR | | Cite: | Atomic-resolution structure of cytoskeletal bactofilin by solid-state NMR.
Sci Adv, 1, 2015
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2O8P
 | | Crystal structure of a putative 14-3-3 protein from Cryptosporidium parvum, cgd7_2470 | | Descriptor: | 14-3-3 domain containing protein | | Authors: | Dong, A, Lew, J, Wasney, G, Lin, L, Hassanali, A, Zhao, Y, Vedadi, M, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Walker, J.R, Bochkarev, A, Hui, R, Brokx, S.J, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-12-12 | | Release date: | 2007-01-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Characterization of 14-3-3 proteins from Cryptosporidium parvum.
Plos One, 6, 2011
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1NY3
 | | Crystal structure of ADP bound to MAP KAP kinase 2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAP kinase-activated protein kinase 2 | | Authors: | Underwood, K.W, Parris, K.D, Federico, E, Mosyak, L, Shane, T, Taylor, M, Svenson, K, Liu, Y, Hsiao, C.L, Wolfrom, S, Maguire, M, Malakian, K, Telliez, J.B, Lin, L.L, Kriz, R.W, Seehra, J, Somers, W.S, Stahl, M.L. | | Deposit date: | 2003-02-11 | | Release date: | 2003-10-14 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme
Structure, 11, 2003
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2OQK
 | | Crystal structure of putative Cryptosporidium parvum translation initiation factor eIF-1A | | Descriptor: | Putative translation initiation factor eIF-1A, SULFATE ION | | Authors: | Dong, A, Lew, J, Zhao, Y, Hassanali, A, Lin, L, Qiu, W, Brokx, S.J, Wasney, G, Vedadi, M, Kozieradzki, I, Bochkarev, A, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Altamentova, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-01-31 | | Release date: | 2007-02-13 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of putative Cryptosporidium parvum translation initiation factor eIF-1A
To be Published
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1NXK
 | | Crystal structure of staurosporine bound to MAP KAP kinase 2 | | Descriptor: | MAP kinase-activated protein kinase 2, STAUROSPORINE, SULFATE ION | | Authors: | Underwood, K.W, Parris, K.D, Federico, E, Mosyak, L, Czerwinski, R.M, Shane, T, Taylor, M, Svenson, K, Liu, Y, Hsiao, C.L, Wolfrom, S, Malakian, K, Telliez, J.B, Lin, L.L, Kriz, R.W, Seehra, J, Somers, W.S, Stahl, M.L. | | Deposit date: | 2003-02-10 | | Release date: | 2003-10-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme
Structure, 11, 2003
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2PLW
 | | Crystal structure of a ribosomal RNA methyltransferase, putative, from Plasmodium falciparum (PF13_0052). | | Descriptor: | Ribosomal RNA methyltransferase, putative, S-ADENOSYLMETHIONINE, ... | | Authors: | Wernimont, A.K, Hassanali, A, Lin, L, Lew, J, Zhao, Y, Ravichandran, M, Wasney, G, Vedadi, M, Kozieradzki, I, Schapira, M, Bochkarev, A, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Qiu, W, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-04-20 | | Release date: | 2007-05-08 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of a ribosomal RNA methyltransferase, putative, from Plasmodium falciparum (PF13_0052).
To be Published
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2Q2G
 | | Crystal structure of dimerization domain of HSP40 from Cryptosporidium parvum, cgd2_1800 | | Descriptor: | Heat shock 40 kDa protein, putative (fragment), SULFATE ION | | Authors: | Wernimont, A.K, Lew, J, Lin, L, Hassanali, A, Kozieradzki, I, Wasney, G, Vedadi, M, Walker, J.R, Zhao, Y, Schapira, M, Bochkarev, A, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Hui, R, Brokx, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-05-28 | | Release date: | 2007-06-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of dimerization domain of HSP40 from Cryptosporidium parvum, cgd2_1800.
To be Published
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2Q0V
 | | Crystal structure of ubiquitin conjugating enzyme E2, putative, from Plasmodium falciparum | | Descriptor: | PHOSPHATE ION, Ubiquitin-conjugating enzyme E2, putative | | Authors: | Wernimont, A.K, Lew, J, Hassanali, A, Lin, L, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Brokx, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-05-22 | | Release date: | 2007-06-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of ubiquitin conjugating enzyme E2, putative, from Plasmodium falciparum.
To be Published
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2PWQ
 | | Crystal structure of a putative ubiquitin conjugating enzyme from Plasmodium yoelii | | Descriptor: | Ubiquitin conjugating enzyme | | Authors: | Qiu, W, Dong, A, Hassanali, A, Lin, L, Brokx, S, Altamentova, S, Hills, T, Lew, J, Ravichandran, M, Kozieradzki, I, Zhao, Y, Schapira, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-05-11 | | Release date: | 2007-05-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of a putative ubiquitin conjugating enzyme from Plasmodium yoelii.
To be Published
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