2AGQ
 
 | | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*CP*TP*AP*CP*AP*GP*GP*AP*CP*TP*(DOC))-3', 5'-D(*TP*CP*AP*TP*GP*AP*GP*TP*CP*CP*TP*GP*TP*AP*GP*CP*C)-3', ... | | 著者 | Ling, H, Yang, W. | | 登録日 | 2005-07-27 | | 公開日 | 2005-09-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis.
Embo J., 24, 2005
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2AGO
 | | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis | | 分子名称: | CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*TP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ... | | 著者 | Ling, H, Yang, W. | | 登録日 | 2005-07-27 | | 公開日 | 2005-09-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis.
Embo J., 24, 2005
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2AGP
 | | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*(DOC)-3'), ... | | 著者 | Ling, H, Yang, W. | | 登録日 | 2005-07-27 | | 公開日 | 2005-09-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis.
Embo J., 24, 2005
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1N48
 | | Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion | | 分子名称: | 5'-D(*CP*AP*(3DR)P*TP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*A)-3', ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Ling, H, Boudsocq, F, Woodgate, R, Yang, W. | | 登録日 | 2002-10-30 | | 公開日 | 2004-02-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A Y-family polymerase complexed with abasic lesions: catching DNA with a loaded nucleoside triphosphate
To be Published
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2IMW
 | | Mechanism of Template-Independent Nucleotide Incorporation Catalyzed by a Template-Dependent DNA Polymerase | | 分子名称: | 1,2-ETHANEDIOL, 2',3'-dideoxyadenosine triphosphate, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3', ... | | 著者 | Ling, H, Yang, W. | | 登録日 | 2006-10-05 | | 公開日 | 2007-01-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Mechanism of Template-independent Nucleotide Incorporation Catalyzed by a Template-dependent DNA Polymerase.
J.Mol.Biol., 365, 2007
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1N56
 | | Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion | | 分子名称: | 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*AP*A)-3', 5'-D(*TP*CP*AP*TP*(3DR)P*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Ling, H, Boudsocq, F, Woodgate, R, Yang, W. | | 登録日 | 2002-11-04 | | 公開日 | 2004-02-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Snapshots of replication through an abasic lesion; structural basis for base substitutions and frameshifts.
Mol.Cell, 13, 2004
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2B5E
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1ORL
 | | 1H NMR structure determination of Viscotoxin C1 | | 分子名称: | Viscotoxin C1 | | 著者 | Molinari, H, Romagnoli, S, Fogolari, F, Catalano, M, Urech, K, Giannattasio, M, Ragona, L. | | 登録日 | 2003-03-14 | | 公開日 | 2003-04-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structure of viscotoxin C1 from Viscum album species Coloratum ohwi: toward a structure-function analysis of viscotoxins.
Biochemistry, 42, 2003
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1P9H
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1Q7L
 | | Zn-binding domain of the T347G mutant of human aminoacylase-I | | 分子名称: | Aminoacylase-1, GLYCINE, ZINC ION | | 著者 | Lindner, H.A, Lunin, V.V, Alary, A, Hecker, R, Cygler, M, Menard, R. | | 登録日 | 2003-08-19 | | 公開日 | 2004-01-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Essential roles of zinc ligation and enzyme dimerization for catalysis in the aminoacylase-1/M20 family.
J.Biol.Chem., 278, 2003
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1CSP
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1D1I
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1D1K
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1CQF
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1EKS
 | | ASP128ALA VARIANT OF MOAC PROTEIN FROM E. COLI | | 分子名称: | L(+)-TARTARIC ACID, MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN C | | 著者 | Schindelin, H, Liu, M.T.W, Wuebbens, M.M, Rajagopalan, K.V. | | 登録日 | 2000-03-09 | | 公開日 | 2000-09-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Insights into molybdenum cofactor deficiency provided by the crystal structure of the molybdenum cofactor biosynthesis protein MoaC.
Structure Fold.Des., 8, 2000
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1EKR
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5H9S
 | | Crystal Structure of Human Galectin-7 in Complex with TAZTDG | | 分子名称: | (2~{S},3~{R},4~{S},5~{R},6~{R})-2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]sulfanyl-6-(hydroxymethyl)oxane-3,4,5-triol, Galectin-7 | | 著者 | Hsieh, T.J, Lin, H.Y, Lin, C.H. | | 登録日 | 2015-12-29 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.821 Å) | | 主引用文献 | Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors
Sci Rep, 6, 2016
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5H9Q
 | | Crystal Structure of Human Galectin-7 in Complex with TD139 | | 分子名称: | 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, Galectin-7 | | 著者 | Hsieh, T.J, Lin, H.Y, Lin, C.H. | | 登録日 | 2015-12-29 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.931 Å) | | 主引用文献 | Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors
Sci Rep, 6, 2016
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5GGE
 | | Fatty Acid-Binding Protein in Brain Tissue of Drosophila melanogaster | | 分子名称: | CITRIC ACID, Fatty acid bindin protein, isoform B | | 著者 | Cheng, Y.-Y, Huang, Y.-F, Lin, H.-H, Chang, W.W, Lyu, P.-C. | | 登録日 | 2016-06-15 | | 公開日 | 2017-06-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.861 Å) | | 主引用文献 | The ligand-mediated affinity of brain-type fatty acid-binding protein for membranes determines the directionality of lipophilic cargo transport.
Biochim Biophys Acta Mol Cell Biol Lipids, 1864, 2019
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9CBT
 | | Crystal structure of human sirtuin 3 fragment (residues 118-399) bound to intermediates from reaction with NAD and inhibitor NH6-10 | | 分子名称: | (phenylmethyl) ~{N}-[(2~{S})-6-[[(2~{R},3~{a}~{R},5~{R},6~{R},6~{a}~{R})-5-[[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-6-oxidanyl-2-tridecyl-3~{a},5,6,6~{a}-tetrahydrofuro[2,3-d][1,3]oxathiol-2-yl]amino]-1-oxidanylidene-1-[2-(triethyl-$l^{4}-azanyl)ethylamino]hexan-2-yl]carbamate, 2-{[(2S)-6-[(Z)-(1-{[(2R,3R,4R,5R)-5-({[(R)-{[(R)-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-4-hydroxy-2-sulfanyloxolan-3-yl]oxy}tetradecylidene)amino]-2-{[(benzyloxy)carbonyl]amino}hexanoyl]amino}-N,N,N-triethylethan-1-aminium (non-preferred name), NAD-dependent protein deacetylase sirtuin-3, ... | | 著者 | Fenwick, M.K, Young, H.J, Lin, H. | | 登録日 | 2024-06-20 | | 公開日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of human sirtuin 3 fragment (residues 118-399) bound to intermediates from reaction with NAD and inhibitor NH6-10
To Be Published
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6DO4
 | | KLHDC2 ubiquitin ligase in complex with SelS C-end degron | | 分子名称: | Kelch domain-containing protein 2, SELS C-END DEGRON | | 著者 | Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N. | | 登録日 | 2018-06-08 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase.
Mol. Cell, 72, 2018
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6DO3
 | | KLHDC2 ubiquitin ligase in complex with SelK C-end degron | | 分子名称: | Kelch domain-containing protein 2, SelK C-end Degron | | 著者 | Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N. | | 登録日 | 2018-06-08 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.165 Å) | | 主引用文献 | Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase.
Mol. Cell, 72, 2018
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8WQM
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6JZ7
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6JZ6
 | | b-glucuronidase from Ruminococcus gnavus in complex with C6-substituted uronic isofagomine | | 分子名称: | (2~{S},3~{S},4~{R},5~{R})-4,5-bis(oxidanyl)-2-propyl-piperidine-3-carboxylic acid, Beta-glucuronidase | | 著者 | Dashnyam, P, Lin, H.Y. | | 登録日 | 2019-04-30 | | 公開日 | 2020-06-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.605 Å) | | 主引用文献 | Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes.
J.Med.Chem., 63, 2020
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