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PDB: 180 results
4PZ8
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BU of 4pz8 by Molmil
PCE1 guanylyltransferase bound to SPT5 CTD
Descriptor: SULFATE ION, Transcription elongation factor spt5, mRNA-capping enzyme subunit alpha
Authors:Doamekpor, S.K, Lima, C.D.
Deposit date:2014-03-28
Release date:2014-06-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes.
Genes Dev., 28, 2014
4PZ6
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BU of 4pz6 by Molmil
PCE1 guanylyltransferase bound to SER2/SER5 phosphorylated RNA pol II CTD
Descriptor: DNA-directed RNA polymerase II subunit rpb1, GUANOSINE, mRNA-capping enzyme subunit alpha
Authors:Doamekpor, S.K, Lima, C.D.
Deposit date:2014-03-28
Release date:2014-06-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes.
Genes Dev., 28, 2014
7S7B
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BU of 7s7b by Molmil
Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1)
Descriptor: Exosome RNA helicase MTR4, RNA (46-MER), RNA-binding protein 7, ...
Authors:Puno, M.R, Lima, C.D.
Deposit date:2021-09-15
Release date:2022-06-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
Cell, 185, 2022
7S7C
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BU of 7s7c by Molmil
Human Nuclear Exosome Targeting (NEXT) complex bound to RNA (substrate 2)
Descriptor: Exosome RNA helicase MTR4, RNA (30-MER), RNA-binding protein 7, ...
Authors:Puno, M.R, Lima, C.D.
Deposit date:2021-09-15
Release date:2022-06-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
Cell, 185, 2022
3RTX
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BU of 3rtx by Molmil
Crystal structure of mammalian capping enzyme (Mce1) and Pol II CTD complex
Descriptor: GUANINE, RNA Polymerase II C-terminal domain, mRNA-capping enzyme
Authors:Ghosh, A, Lima, C.D.
Deposit date:2011-05-04
Release date:2011-06-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural insights to how mammalian capping enzyme reads the CTD code.
Mol.Cell, 43, 2011
3SAF
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BU of 3saf by Molmil
Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site
Descriptor: Exosome component 10, MAGNESIUM ION, YTTRIUM (III) ION
Authors:Januszyk, K, Liu, Q, Lima, C.D.
Deposit date:2011-06-02
Release date:2011-07-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Activities of human RRP6 and structure of the human RRP6 catalytic domain.
Rna, 17, 2011
3SAG
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BU of 3sag by Molmil
Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site
Descriptor: Exosome component 10, MAGNESIUM ION, YTTRIUM (III) ION
Authors:Januszyk, K, Liu, Q, Lima, C.D.
Deposit date:2011-06-02
Release date:2011-07-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Activities of human RRP6 and structure of the human RRP6 catalytic domain.
Rna, 17, 2011
3SAH
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BU of 3sah by Molmil
Crystal structure of the human RRP6 catalytic domain with Y436A mutation in the catalytic site
Descriptor: Exosome component 10, MAGNESIUM ION, YTTRIUM (III) ION
Authors:Januszyk, K, Liu, Q, Lima, C.D.
Deposit date:2011-06-02
Release date:2011-07-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Activities of human RRP6 and structure of the human RRP6 catalytic domain.
Rna, 17, 2011
4II2
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BU of 4ii2 by Molmil
Crystal structure of Ubiquitin activating enzyme 1 (Uba1) in complex with the Ub E2 Ubc4, ubiquitin, and ATP/Mg
Descriptor: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Olsen, S.K, Lima, C.D.
Deposit date:2012-12-19
Release date:2013-02-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer.
Mol.Cell, 49, 2013
9B5E
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BU of 9b5e by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - Ub(T) class 10 map and model from consensus
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5O
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BU of 9b5o by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 10 map and model from consensus
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
4II3
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BU of 4ii3 by Molmil
Crystal structure of S. pombe Ubiquitin activating enzyme 1 (Uba1) in complex with ubiquitin and ATP/Mg
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ...
Authors:Olsen, S.K, Lima, C.D.
Deposit date:2012-12-19
Release date:2013-02-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer.
Mol.Cell, 49, 2013
9B58
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BU of 9b58 by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 4
Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5D
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BU of 9b5d by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - Ub(T) class 1 map and model from consensus
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5J
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BU of 9b5j by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 5 map and model (Ub(A)-AMP)
Descriptor: 4-aminobutanenitrile, ADENOSINE MONOPHOSPHATE, Large ribosomal subunit protein eL40B, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5U
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BU of 9b5u by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 1 map and model from cluster 1 (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B55
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BU of 9b55 by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 1
Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B59
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BU of 9b59 by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 5
Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5G
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BU of 9b5g by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 2 map and model (Ub(A)/ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.67 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5P
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BU of 9b5p by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - cluster 1 map and model (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5W
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BU of 9b5w by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 1 map and model from cluster 5 (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5K
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BU of 9b5k by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - Ub(T) class 1 map and model from cluster 1 (Ub(A)/ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5T
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BU of 9b5t by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - cluster 5 map and model (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B57
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BU of 9b57 by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 3
Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5C
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BU of 9b5c by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - consensus map and model
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024

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