1W99
 
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3KB3
 | | Crystal structure of abscisic acid-bound PYL2 in complex with HAB1 | | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, MAGNESIUM ION, Protein phosphatase 2C 16, ... | | 著者 | Zhou, X.E, Melcher, K, Soon, F.-F, Ng, L.-M, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Xu, H.E. | | 登録日 | 2009-10-20 | | 公開日 | 2009-12-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
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4ELW
 | | Structure of E. coli. 1,4-dihydroxy-2- naphthoyl coenzyme A synthases (MENB) in complex with nitrate | | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, CHLORIDE ION, GLYCEROL, ... | | 著者 | Sun, Y.R, Song, H.G, Li, J, Jiang, M, Li, Y, Zhou, J.H, Guo, Z.H. | | 登録日 | 2012-04-11 | | 公開日 | 2012-06-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.551 Å) | | 主引用文献 | Active site binding and catalytic role of bicarbonate in 1,4-dihydroxy-2-naphthoyl coenzyme A synthases from vitamin K biosynthetic pathways
Biochemistry, 51, 2012
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5JI8
 | | Crystal structure of the BRD9 bromodomain and hit 1 | | 分子名称: | 2-amino-1,3-benzothiazole-6-carboxamide, Bromodomain-containing protein 9 | | 著者 | Wang, N, Li, F, Bao, H, Li, J, Wu, J, Ruan, K. | | 登録日 | 2016-04-22 | | 公開日 | 2016-06-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | NMR Fragment Screening Hit Induces Plasticity of BRD7/9 Bromodomains
Chembiochem, 17, 2016
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1WUG
 | | complex structure of PCAF bromodomain with small chemical ligand NP1 | | 分子名称: | Histone acetyltransferase PCAF, N-(3-AMINOPROPYL)-4-METHYL-2-NITROBENZENAMINE | | 著者 | Zeng, L, Li, J, Muller, M, Yan, S, Mujtaba, S, Pan, C, Wang, Z, Zhou, M.M. | | 登録日 | 2004-12-07 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Selective small molecules blocking HIV-1 Tat and coactivator PCAF association
J.Am.Chem.Soc., 127, 2005
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1WUM
 | | Complex structure of PCAF bromodomain with small chemical ligand NP2 | | 分子名称: | Histone acetyltransferase PCAF, N-(3-AMINOPROPYL)-2-NITROBENZENAMINE | | 著者 | Zeng, L, Li, J, Muller, M, Yan, S, Mujtaba, S, Pan, C, Wang, Z, Zhou, M.M. | | 登録日 | 2004-12-08 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Selective small molecules blocking HIV-1 Tat and coactivator PCAF association
J.Am.Chem.Soc., 127, 2005
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4Y07
 | | Crystal structure of the HECT domain of human WWP2 | | 分子名称: | NEDD4-like E3 ubiquitin-protein ligase WWP2 | | 著者 | Gong, W, Li, J, Li, Z, Xu, Y. | | 登録日 | 2015-02-05 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.507 Å) | | 主引用文献 | Structure of the HECT domain of human WWP2
Acta Crystallogr.,Sect.F, 71, 2015
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8C54
 | | Cryo-EM structure of NADH bound SLA dehydrogenase RlGabD from Rhizobium leguminosarum bv. trifolii SRD1565 | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Succinate semialdehyde dehydrogenase | | 著者 | Sharma, M, Meek, R.W, Armstrong, Z, Blaza, J.N, Alhifthi, A, Li, J, Goddard-Borger, E.D, Williams, S.J, Davies, G.J. | | 登録日 | 2023-01-06 | | 公開日 | 2023-09-20 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | | 主引用文献 | Molecular basis of sulfolactate synthesis by sulfolactaldehyde dehydrogenase from Rhizobium leguminosarum.
Chem Sci, 14, 2023
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2R2N
 | | The crystal structure of human kynurenine aminotransferase II in complex with kynurenine | | 分子名称: | (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, GLYCEROL, ... | | 著者 | Han, Q, Robinson, H, Li, J. | | 登録日 | 2007-08-27 | | 公開日 | 2007-12-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of human kynurenine aminotransferase II.
J.Biol.Chem., 283, 2008
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2QLD
 | | human Hsp40 Hdj1 | | 分子名称: | DnaJ homolog subfamily B member 1 | | 著者 | Hu, J, Wu, Y, Li, J, Fu, Z, Sha, B. | | 登録日 | 2007-07-12 | | 公開日 | 2008-07-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The crystal structure of the putative peptide-binding fragment from the human Hsp40 protein Hdj1.
Bmc Struct.Biol., 8, 2008
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2QTW
 | | The Crystal Structure of PCSK9 at 1.9 Angstroms Resolution Reveals structural homology to Resistin within the C-terminal domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Proprotein convertase subtilisin/kexin type 9, ... | | 著者 | Hampton, E.N, Knuth, M.W, Li, J, Harris, J.L, Lesley, S.A, Spraggon, G. | | 登録日 | 2007-08-02 | | 公開日 | 2007-09-18 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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4N6F
 | | Crystal structure of Amycolatopsis orientalis BexX complexed with G6P | | 分子名称: | CALCIUM ION, FRUCTOSE -6-PHOSPHATE, Putative thiosugar synthase | | 著者 | Zhang, X, Zhang, Y, Kinsland, C, Sasaki, E, Sun, H.G, Lu, M.J, Liu, T, Ou, A, Li, J, Chen, Y, Liu, H, Ealick, S.E. | | 登録日 | 2013-10-11 | | 公開日 | 2014-05-14 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis.
Nature, 509, 2014
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3KQI
 | | crystal structure of PHF2 PHD domain complexed with H3K4Me3 peptide | | 分子名称: | CHLORIDE ION, GLYCEROL, H3K4Me3 peptide, ... | | 著者 | Wen, H, Li, J.Z, Song, T, Lu, M, Lee, M. | | 登録日 | 2009-11-17 | | 公開日 | 2010-02-02 | | 最終更新日 | 2019-02-13 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation.
J.Biol.Chem., 285, 2010
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4N6E
 | | Crystal structure of Amycolatopsis orientalis BexX/CysO complex | | 分子名称: | Putative thiosugar synthase, SULFATE ION, ThiS/MoaD family protein | | 著者 | Zhang, X, Zhang, Y, Kinsland, C, Sasaki, E, Sun, H.G, Lu, M.J, Liu, T, Ou, A, Li, J, Chen, Y, Liu, H, Ealick, S.E. | | 登録日 | 2013-10-11 | | 公開日 | 2014-05-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis.
Nature, 509, 2014
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4MYD
 | | 1.37 Angstrom Crystal Structure of E. Coli 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (MenH) in complex with SHCHC | | 分子名称: | 2-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase | | 著者 | Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z. | | 登録日 | 2013-09-27 | | 公開日 | 2014-04-23 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.374 Å) | | 主引用文献 | Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad.
J.Biol.Chem., 289, 2014
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4MXD
 | | 1.45 angstronm crystal structure of E.coli 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (MenH) | | 分子名称: | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z. | | 登録日 | 2013-09-26 | | 公開日 | 2014-04-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad.
J.Biol.Chem., 289, 2014
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6XLT
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3UC4
 | | The crystal structure of Snf1-related kinase 2.6 | | 分子名称: | Serine/threonine-protein kinase SRK2E | | 著者 | Zhou, X.E, Ng, L.-M, Soon, F.-F, Kovach, A, Suino-Powell, K.M, Li, J, Melcher, K, Xu, H.E. | | 登録日 | 2011-10-26 | | 公開日 | 2011-12-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3L3Z
 | | Crystal structure of DHT-bound androgen receptor in complex with the third motif of steroid receptor coactivator 3 | | 分子名称: | 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor coactivator 3 | | 著者 | Zhou, X.E, Suino-Powell, K.M, Li, J, He, A, MacKeigan, J.P, Melcher, K, Yong, E.-L, Xu, H.E. | | 登録日 | 2009-12-18 | | 公開日 | 2010-01-12 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor.
J.Biol.Chem., 285, 2010
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3L3X
 | | Crystal structure of DHT-bound androgen receptor in complex with the first motif of steroid receptor coactivator 3 | | 分子名称: | 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor coactivator 3 | | 著者 | Zhou, X.E, Suino-Powell, K.M, Li, J, He, A, MacKeigan, J.P, Melcher, K, Yong, E.-L, Xu, H.E. | | 登録日 | 2009-12-18 | | 公開日 | 2010-01-12 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor.
J.Biol.Chem., 285, 2010
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5JHH
 | | Crystal structure of the ternary complex between the human RhoA, its inhibitor and the DH/PH domain of human ARHGEF11 | | 分子名称: | 3-{3-[ethyl(quinolin-2-yl)amino]phenyl}propanoic acid, GLYCEROL, Rho guanine nucleotide exchange factor 11, ... | | 著者 | Lv, Z, Wang, R, Ma, L, Miao, Q, Wu, J, Yan, Z, Li, J, Miao, L, Wang, F. | | 登録日 | 2016-04-21 | | 公開日 | 2017-04-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and PDZRhoGEF
To Be Published
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8H8D
 | | Structure of Xenopus tropicalis acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (intermediate state) | | 分子名称: | Proton-activated chloride channel | | 著者 | Chi, P, Wang, X, Li, J, Li, K, Zhang, Y, Geng, J, Wu, J, Deng, D. | | 登録日 | 2022-10-22 | | 公開日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (4.26 Å) | | 主引用文献 | Structure of Xenopus tropicalis acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (intermediate state)
To Be Published
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8H8F
 | | Structure of Xenopus tropicalis acid-sensitive outwardly rectifying channel ASOR (resting state) | | 分子名称: | Proton-activated chloride channel | | 著者 | Chi, P, Wang, X, Li, J, Li, K, Zhang, Y, Geng, J, Wu, J, Deng, D. | | 登録日 | 2022-10-22 | | 公開日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | Structure of Xenopus tropicalis acid-sensitive outwardly rectifying channel ASOR (resting state)
To Be Published
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8H8E
 | | Structure of the dimeric Xenopus tropical acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (closed state) | | 分子名称: | Proton-activated chloride channel, tRNA (75-MER)of Spodoptera frugiperda | | 著者 | Chi, P, Wang, X, Li, J, Li, K, Zhang, Y, Geng, J, Wu, J, Deng, D. | | 登録日 | 2022-10-22 | | 公開日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.81 Å) | | 主引用文献 | Structure of the dimeric Xenopus tropical acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (closed state)
To Be Published
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8H94
 | | Structure of mouse SCMC bound with KH domain of FILIA | | 分子名称: | NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ... | | 著者 | Chi, P, Ou, G, Han, Z, Li, J, Deng, D. | | 登録日 | 2022-10-24 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of the subcortical maternal complex and its implications in reproductive disorders.
Nat.Struct.Mol.Biol., 31, 2024
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