6KEF
 
 | | BRD4 Bromodomain1 with an inhibitor | | 分子名称: | Bromodomain-containing protein 4, N-[3-(8-methyl-1-oxidanylidene-2H-pyrrolo[1,2-a]pyrazin-6-yl)-4-phenoxy-phenyl]methanesulfonamide | | 著者 | Xiao, S, Li, Z, Chen, S, Zhou, B, Luo, C. | | 登録日 | 2019-07-04 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.44467545 Å) | | 主引用文献 | BRD4 Bromodomain1 with an inhibitor
To Be Published
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6KL9
 | | Structure of LbCas12a-crRNA complex bound to AcrVA4 (form A complex) | | 分子名称: | AcrVA4, LbCas12a, MAGNESIUM ION, ... | | 著者 | Peng, R, Li, Z, Xu, Y, He, S, Peng, Q, Shi, Y, Gao, G.F. | | 登録日 | 2019-07-30 | | 公開日 | 2019-09-11 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6KED
 | | BRD4 Bromodomain1 with an inhibitor | | 分子名称: | 6-[2-[2,4-bis(fluoranyl)phenoxy]-5-(methylsulfonylmethyl)pyridin-3-yl]-8-methyl-2H-pyrrolo[1,2-d][1,2,4]triazin-1-one, Bromodomain-containing protein 4 | | 著者 | Xiao, S, Li, Z, Chen, S, Zhou, B, Luo, C. | | 登録日 | 2019-07-04 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.548447 Å) | | 主引用文献 | BRD4 Bromodomain1 with an inhibitor
To Be Published
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7V55
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7V53
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6KLB
 | | Structure of LbCas12a-crRNA complex bound to AcrVA4 (form B complex) | | 分子名称: | AcrVA4, LbCas12a, MAGNESIUM ION, ... | | 著者 | Peng, R, Li, Z, Xu, Y, He, S, Peng, Q, Shi, Y, Gao, G.F. | | 登録日 | 2019-07-30 | | 公開日 | 2019-09-11 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4.
Proc.Natl.Acad.Sci.USA, 116, 2019
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5XGP
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7VPA
 | | Crystal structure of Ple629 from marine microbial consortium | | 分子名称: | hydrolase Ple629 | | 著者 | Wu, P, Zhao, Y.P, Li, Z.S, Ingrid, M.C, Lara, P, Gao, J, Han, X, Li, Q, Basak, O, Liu, W.D, Wei, R. | | 登録日 | 2021-10-15 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Molecular and Biochemical Differences of the Tandem and Cold-Adapted PET Hydrolases Ple628 and Ple629, Isolated From a Marine Microbial Consortium.
Front Bioeng Biotechnol, 10, 2022
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7VMD
 | | Crystal structure of a hydrolases Ple628 from marine microbial consortium | | 分子名称: | CALCIUM ION, hydrolase Ple628 | | 著者 | Wu, P, Zhao, Y.P, Li, Z.S, Ingrid, M.C, Lara, P, Gao, J, Han, X, Li, Q, Basak, O, Liu, W.D, Wei, R. | | 登録日 | 2021-10-08 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Molecular and Biochemical Differences of the Tandem and Cold-Adapted PET Hydrolases Ple628 and Ple629, Isolated From a Marine Microbial Consortium.
Front Bioeng Biotechnol, 10, 2022
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7W8N
 | | Microbial Hormone-sensitive lipase E53 wild type | | 分子名称: | (4-nitrophenyl) hexanoate, 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, ... | | 著者 | Yang, X, Li, Z, Xu, X, Li, J. | | 登録日 | 2021-12-08 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Mechanism and Structural Insights Into a Novel Esterase, E53, Isolated From Erythrobacter longus .
Front Microbiol, 12, 2021
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5YBZ
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5X0M
 | | Structure of a eukaryotic voltage-gated sodium channel at near atomic resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium channel protein, ... | | 著者 | Shen, H, Zhou, Q, Pan, X, Li, Z, Wu, J, Yan, N. | | 登録日 | 2017-01-21 | | 公開日 | 2017-03-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution.
Science, 355, 2017
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7YE9
 | | SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32 Fab, ... | | 著者 | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | | 登録日 | 2022-07-05 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | | 主引用文献 | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope.
Nat Microbiol, 7, 2022
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5ZF3
 | | Crystal Structures of Endo-beta-1,4-xylanase II Complexed with Xylotriose | | 分子名称: | Endo-1,4-beta-xylanase 2, GLYCEROL, IODIDE ION, ... | | 著者 | Zhang, X, Wan, Q, Li, Z. | | 登録日 | 2018-03-02 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Crystal Structures of Endo-beta-1,4-xylanase II Complexed with Xylotriose
To be published
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5ZH0
 | | Crystal Structures of Endo-beta-1,4-xylanase II | | 分子名称: | Endo-1,4-beta-xylanase 2, GLYCEROL, IODIDE ION | | 著者 | Zhang, X, Wan, Q, Li, Z. | | 登録日 | 2018-03-10 | | 公開日 | 2019-03-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | | 主引用文献 | Crystal Structures of Endo-beta-1,4-xylanase II
To be published
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7F0D
 | | Cryo-EM structure of Mycobacterium tuberculosis 50S ribosome subunit bound with clarithromycin | | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Zhang, W, Sun, Y, Gao, N, Li, Z. | | 登録日 | 2021-06-03 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structure of Mycobacterium tuberculosis 50S ribosomal subunit bound with clarithromycin reveals dynamic and specific interactions with macrolides.
Emerg Microbes Infect, 11, 2022
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7DTC
 | | voltage-gated sodium channel Nav1.5-E1784K | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium channel protein type 5 subunit alpha | | 著者 | Yan, N, Pan, X, Li, Z. | | 登録日 | 2021-01-04 | | 公開日 | 2021-03-24 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure of human Na v 1.5 reveals the fast inactivation-related segments as a mutational hotspot for the long QT syndrome.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7YFV
 | | Structure of Rpgrip1l CC1 | | 分子名称: | Protein fantom | | 著者 | He, R, Chen, G, Li, Z, Li, J. | | 登録日 | 2022-07-09 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the N-terminal coiled-coil domains of the ciliary protein Rpgrip1l.
Iscience, 26, 2023
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7YFU
 | | Structure of Rpgrip1l CC2 | | 分子名称: | Protein fantom | | 著者 | He, R, Chen, G, Li, Z, Li, J. | | 登録日 | 2022-07-09 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of the N-terminal coiled-coil domains of the ciliary protein Rpgrip1l.
Iscience, 26, 2023
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1ULW
 | | Crystal structure of P450nor Ser73Gly/Ser75Gly mutant | | 分子名称: | Cytochrome P450 55A1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Oshima, R, Fushinobu, S, Su, F, Li, Z, Takaya, N, Shoun, H. | | 登録日 | 2003-09-16 | | 公開日 | 2004-10-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural evidence for direct hydride transfer from NADH to cytochrome P450nor
J.Mol.Biol., 342, 2004
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5X3P
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5X4L
 | | Crystal structure of the UBX domain of human UBXD7 in complex with p97 N domain | | 分子名称: | Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 7 | | 著者 | Jiang, T, Li, Z, Wang, Y, Xu, M. | | 登録日 | 2017-02-13 | | 公開日 | 2017-03-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | | 主引用文献 | Crystal structures of the UBX domain of human UBXD7 and its complex with p97 ATPase
Biochem. Biophys. Res. Commun., 486, 2017
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7W66
 | | Crystal structure of a PSH1 mutant in complex with ligand | | 分子名称: | PSH1, bis(2-hydroxyethyl) benzene-1,4-dicarboxylate | | 著者 | Gao, J, Lara, P, Li, Z.S, Han, X, Wei, R, Liu, W.D. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
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7W6C
 | | Crystal structure of a PSH1 in complex with ligand J1K | | 分子名称: | 4-(2-hydroxyethylcarbamoyl)benzoic acid, PSH1 | | 著者 | Gao, J, Lara, P, Li, Z.S, Han, X, Wei, R, Liu, W.D. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
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7W69
 | | Crystal structure of a PSH1 mutant in complex with EDO | | 分子名称: | 1,2-ETHANEDIOL, PSH1 | | 著者 | Gao, J, Lara, P, Li, Z.S, Han, X, Wei, R, Liu, W.D. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
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