6KLB

Structure of LbCas12a-crRNA complex bound to AcrVA4 (form B complex)

Summary for 6KLB

• Entry DOI: 10.2210/pdb6klb/pdb
• EMDB information: 0705
• Descriptor: LbCas12a, AcrVA4, crRNA, ... (5 entities in total)
• Functional Keywords: crispr-cas, anti-crispr, rna binding protein, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Lachnospiraceae bacterium; More
• Total number of polymer chains: 6
• Total formula weight: 369576.30

Authors

Peng, R.,Li, Z.,Xu, Y.,He, S.,Peng, Q.,Shi, Y.,Gao, G.F. (deposition date: 2019-07-30, release date: 2019-09-11, Last modification date: 2019-11-06)

• Primary citation: Peng, R.,Li, Z.,Xu, Y.,He, S.,Peng, Q.,Wu, L.A.,Wu, Y.,Qi, J.,Wang, P.,Shi, Y.,Gao, G.F.; Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4.; Proc.Natl.Acad.Sci.USA, 116:18928-18936, 2019; PubMed: 31467167; DOI: 10.1073/pnas.1909400116

Experimental method

ELECTRON MICROSCOPY (4.1 Å)