5XGP

structure of Sizzled from Xenopus laevis at 2.08 angstroms resolution

Summary for 5XGP

DescriptorSecreted Xwnt8 inhibitor sizzled, SULFATE ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywordssecreted protein, unknown function
Biological sourceXenopus laevis (African clawed frog)
Total number of polymer chains1
Total molecular weight30268.69
Authors
Liu, H.,Li, Z.,Xu, F. (deposition date: 2017-04-15, release date: 2017-08-23, Last modification date: 2019-12-04)
Primary citation
Bu, Q.,Li, Z.,Zhang, J.,Xu, F.,Liu, J.,Liu, H.
The crystal structure of full-length Sizzled from Xenopus laevis yields insights into Wnt-antagonistic function of secreted Frizzled-related proteins
J. Biol. Chem., 292:16055-16069, 2017
PubMed: 28808056 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M117.791756
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.077 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23010 1.4% 10.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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168889
PDB entries from 2020-09-16