5XGP
structure of Sizzled from Xenopus laevis at 2.08 angstroms resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0007165 | biological_process | signal transduction |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0016055 | biological_process | Wnt signaling pathway |
| A | 0017147 | molecular_function | Wnt-protein binding |
| A | 0030154 | biological_process | cell differentiation |
| A | 0035567 | biological_process | non-canonical Wnt signaling pathway |
| A | 0060070 | biological_process | canonical Wnt signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | LYS26 |
| A | VAL28 |
| A | LEU47 |
| A | ASN55 |
| A | MET56 |
| A | HOH417 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | LEU70 |
| A | GLN71 |
| A | ARG79 |
| A | ALA35 |
| A | MET36 |
| A | GLN67 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 303 |
| Chain | Residue |
| A | ASN178 |
| A | ARG258 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 304 |
| Chain | Residue |
| A | GLU58 |
| A | LEU161 |
| A | ILE162 |
| A | LYS234 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 305 |
| Chain | Residue |
| A | PRO240 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 307 |
| Chain | Residue |
| A | CYS115 |
| A | SER155 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 309 |
| Chain | Residue |
| A | GLN263 |
| A | LYS264 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 310 |
| Chain | Residue |
| A | ASN179 |
| A | HOH414 |
