7F0D
Cryo-EM structure of Mycobacterium tuberculosis 50S ribosome subunit bound with clarithromycin
Summary for 7F0D
Entry DOI | 10.2210/pdb7f0d/pdb |
EMDB information | 31398 |
Descriptor | 50S ribosomal protein L32, 50S ribosomal protein L3, 50S ribosomal protein L4, ... (34 entities in total) |
Functional Keywords | mycobacterium tuberculosis;50s ribosomal subunit;gate site a2062;clarithromycin; dynamic interaction;cryo-em;drug resistance, ribosome |
Biological source | Mycobacterium tuberculosis H37Ra More |
Total number of polymer chains | 31 |
Total formula weight | 1458903.71 |
Authors | |
Primary citation | Zhang, W.,Li, Z.,Sun, Y.,Cui, P.,Liang, J.,Xing, Q.,Wu, J.,Xu, Y.,Zhang, W.,Zhang, Y.,He, L.,Gao, N. Cryo-EM structure of Mycobacterium tuberculosis 50S ribosomal subunit bound with clarithromycin reveals dynamic and specific interactions with macrolides. Emerg Microbes Infect, 11:293-305, 2022 Cited by PubMed: 34935599DOI: 10.1080/22221751.2021.2022439 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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