7F0D

Cryo-EM structure of Mycobacterium tuberculosis 50S ribosome subunit bound with clarithromycin

Summary for 7F0D

Entry DOI	10.2210/pdb7f0d/pdb
EMDB information	31398
Descriptor	50S ribosomal protein L32, 50S ribosomal protein L3, 50S ribosomal protein L4, ... (34 entities in total)
Functional Keywords	mycobacterium tuberculosis;50s ribosomal subunit;gate site a2062;clarithromycin; dynamic interaction;cryo-em;drug resistance, ribosome
Biological source	Mycobacterium tuberculosis H37Ra More
Total number of polymer chains	31
Total formula weight	1458903.71
Authors	Zhang, W.,Sun, Y.,Gao, N.,Li, Z. (deposition date: 2021-06-03, release date: 2022-06-29)
Primary citation	Zhang, W.,Li, Z.,Sun, Y.,Cui, P.,Liang, J.,Xing, Q.,Wu, J.,Xu, Y.,Zhang, W.,Zhang, Y.,He, L.,Gao, N. Cryo-EM structure of Mycobacterium tuberculosis 50S ribosomal subunit bound with clarithromycin reveals dynamic and specific interactions with macrolides. Emerg Microbes Infect, 11:293-305, 2022 Cited by PubMed: 34935599 DOI: 10.1080/22221751.2021.2022439 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation