6C9J
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![BU of 6c9j by Molmil](/molmil-images/mine/6c9j) | AMP-activated protein kinase bound to pharmacological activator R734 | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... | Authors: | Yan, Y, Zhou, X.E, Novick, S, Shaw, S.J, Li, Y, Brunzelle, J.S, Hitoshi, Y, Griffin, P.R, Xu, H.E, Melcher, K. | Deposit date: | 2018-01-26 | Release date: | 2018-11-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states. J. Biol. Chem., 294, 2019
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5J3E
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![BU of 5j3e by Molmil](/molmil-images/mine/5j3e) | Crystal Structure of Human THYN1 protein in complex with 5-methylcytosine containing DNA | Descriptor: | 5-methylcytosine containing DNA, Thymocyte nuclear protein 1, UNKNOWN ATOM OR ION | Authors: | Halabelian, L, Tempel, W, Li, Y, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | Deposit date: | 2016-03-30 | Release date: | 2016-04-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of Human THYN1 protein in complex with 5-methylcytosine containing DNA To be published
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6C9H
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![BU of 6c9h by Molmil](/molmil-images/mine/6c9h) | non-phosphorylated AMP-activated protein kinase bound to pharmacological activator R734 | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... | Authors: | Yan, Y, Zhou, X.E, Novick, S, Shaw, S.J, Li, Y, Hitoshi, Y, Brunzelle, J.S, Griffin, P.R, Xu, H.E, Melcher, K. | Deposit date: | 2018-01-26 | Release date: | 2018-11-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states. J. Biol. Chem., 294, 2019
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2P2O
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![BU of 2p2o by Molmil](/molmil-images/mine/2p2o) | Crystal structure of maltose transacetylase from Geobacillus kaustophilus P2(1) crystal form | Descriptor: | Maltose transacetylase | Authors: | Liu, Z.J, Li, Y, Chen, L, Zhu, J, Rose, J.P, Ebihara, A, Yokoyama, S, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-07 | Release date: | 2007-05-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Crystal Structure of Maltose Transacetylase from Geobacillus Kaustophilus at 1.8 Angstrom Resolution To be Published
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6C9G
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![BU of 6c9g by Molmil](/molmil-images/mine/6c9g) | AMP-activated protein kinase bound to pharmacological activator R739 | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-1,5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... | Authors: | Yan, Y, Zhou, X.E, Novick, S, Shaw, S.J, Li, Y, Hitoshi, Y, Brunzelle, J.S, Griffin, P.R, Xu, H.E, Melcher, K. | Deposit date: | 2018-01-26 | Release date: | 2018-11-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states. J. Biol. Chem., 294, 2019
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7YFG
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![BU of 7yfg by Molmil](/molmil-images/mine/7yfg) | Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine and glutamate (major class in asymmetry) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | Authors: | Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S. | Deposit date: | 2022-07-08 | Release date: | 2023-03-29 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits. Nat.Struct.Mol.Biol., 30, 2023
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6C9F
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![BU of 6c9f by Molmil](/molmil-images/mine/6c9f) | AMP-activated protein kinase bound to pharmacological activator R734 | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-1,5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... | Authors: | Yan, Y, Zhou, X.E, Novick, S, Shaw, S.J, Li, Y, Hitoshi, Y, Brunzelle, J.S, Griffin, P.R, Xu, H.E, Melcher, K. | Deposit date: | 2018-01-26 | Release date: | 2018-11-28 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.924 Å) | Cite: | Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states. J. Biol. Chem., 294, 2019
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7YFH
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![BU of 7yfh by Molmil](/molmil-images/mine/7yfh) | Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine, glutamate and (R)-PYD-106 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | Authors: | Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S. | Deposit date: | 2022-07-08 | Release date: | 2023-03-29 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits. Nat.Struct.Mol.Biol., 30, 2023
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5KO9
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![BU of 5ko9 by Molmil](/molmil-images/mine/5ko9) | Crystal Structure of the SRAP Domain of Human HMCES Protein | Descriptor: | Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein, UNKNOWN ATOM OR ION | Authors: | Halabelian, L, Li, Y, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | Deposit date: | 2016-06-29 | Release date: | 2016-08-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition. Nat.Struct.Mol.Biol., 26, 2019
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2P91
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![BU of 2p91 by Molmil](/molmil-images/mine/2p91) | Crystal structure of Enoyl-[acyl-carrier-protein] reductase (NADH) from Aquifex aeolicus VF5 | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADH] | Authors: | Chen, L, Li, Y, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Zhao, M, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-23 | Release date: | 2007-04-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of Enoyl-[acyl-carrier-protein] reductase (NADH) from Aquifex aeolicus VF5 To be Published
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2PG0
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![BU of 2pg0 by Molmil](/molmil-images/mine/2pg0) | Crystal structure of acyl-CoA dehydrogenase from Geobacillus kaustophilus | Descriptor: | Acyl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Chen, L, Chen, L.-Q, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Zhao, M, Li, Y, Fu, Z.-Q, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-06 | Release date: | 2007-05-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of acyl-CoA dehydrogenase from G. kaustophilus To be Published
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1SBZ
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![BU of 1sbz by Molmil](/molmil-images/mine/1sbz) | Crystal Structure of dodecameric FMN-dependent Ubix-like Decarboxylase from Escherichia coli O157:H7 | Descriptor: | FLAVIN MONONUCLEOTIDE, Probable aromatic acid decarboxylase | Authors: | Rangarajan, E.S, Li, Y, Iannuzzi, P, Tocilj, A, Hung, L.-W, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2004-02-11 | Release date: | 2004-10-26 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a dodecameric FMN-dependent UbiX-like decarboxylase (Pad1) from Escherichia coli O157: H7. Protein Sci., 13, 2004
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1WM8
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![BU of 1wm8 by Molmil](/molmil-images/mine/1wm8) | Solution Structure of BmP03 from the Venom of Scorpion Buthus martensii Karsch, 10 structures | Descriptor: | Neurotoxin BmP03 | Authors: | Wu, H, He, F, Li, Y, Wu, G, Cao, C, Chen, X. | Deposit date: | 2004-07-05 | Release date: | 2004-07-27 | Last modified: | 2018-04-18 | Method: | SOLUTION NMR | Cite: | Three-Dimensional Structure of BmP03 from Venom of Scorpion Buthus martensii Karsch Acta Chim.Sinica, 58, 2000
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1WT8
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![BU of 1wt8 by Molmil](/molmil-images/mine/1wt8) | Solution Structure of BmP08 from the Venom of Scorpion Buthus martensii Karsch, 20 structures | Descriptor: | Neurotoxin BmK X | Authors: | Wu, H, Chen, X, Tong, X, Li, Y, Zhang, N, Wu, G. | Deposit date: | 2004-11-17 | Release date: | 2005-04-19 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution structure of BmP08, a novel short-chain scorpion toxin from Buthus martensi Karsch. Biochem.Biophys.Res.Commun., 330, 2005
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2MQ6
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![BU of 2mq6 by Molmil](/molmil-images/mine/2mq6) | |
1WM7
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![BU of 1wm7 by Molmil](/molmil-images/mine/1wm7) | Solution Structure of BmP01 from the Venom of Scorpion Buthus martensii Karsch, 9 structures | Descriptor: | Neurotoxin BmP01 | Authors: | Wu, G, Li, Y, Wei, D, He, F, Jiang, S, Hu, G, Wu, H, Chen, X. | Deposit date: | 2004-07-05 | Release date: | 2004-07-27 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution Structure of BmP01 from the Venom of Scorpion Buthus martensii Karsch Biochem.Biophys.Res.Commun., 276, 2000
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2ITY
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![BU of 2ity by Molmil](/molmil-images/mine/2ity) | Crystal structure of EGFR kinase domain in complex with Iressa | Descriptor: | EPIDERMAL GROWTH FACTOR RECEPTOR, Gefitinib | Authors: | Yun, C.-H, Boggon, T.J, Li, Y, Woo, S, Greulich, H, Meyerson, M, Eck, M.J. | Deposit date: | 2006-05-25 | Release date: | 2007-04-03 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity Cancer Cell, 11, 2007
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2ITP
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![BU of 2itp by Molmil](/molmil-images/mine/2itp) | Crystal structure of EGFR kinase domain G719S mutation in complex with AEE788 | Descriptor: | 6-{4-[(4-ETHYLPIPERAZIN-1-YL)METHYL]PHENYL}-N-[(1R)-1-PHENYLETHYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE, EPIDERMAL GROWTH FACTOR RECEPTOR PRECURSOR | Authors: | Yun, C.-H, Boggon, T.J, Li, Y, Woo, S, Greulich, H, Meyerson, M, Eck, M.J. | Deposit date: | 2006-05-25 | Release date: | 2007-04-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity Cancer Cell, 11, 2007
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2ITW
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![BU of 2itw by Molmil](/molmil-images/mine/2itw) | Crystal structure of EGFR kinase domain in complex with AFN941 | Descriptor: | 1,2,3,4-Tetrahydrogen Staurosporine, EPIDERMAL GROWTH FACTOR RECEPTOR | Authors: | Yun, C.-H, Boggon, T.J, Li, Y, Woo, S, Greulich, H, Meyerson, M, Eck, M.J. | Deposit date: | 2006-05-25 | Release date: | 2007-04-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity Cancer Cell, 11, 2007
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2J0M
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![BU of 2j0m by Molmil](/molmil-images/mine/2j0m) | Crystal structure a two-chain complex between the FERM and kinase domains of focal adhesion kinase. | Descriptor: | 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, FOCAL ADHESION KINASE 1 | Authors: | Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J. | Deposit date: | 2006-08-03 | Release date: | 2007-07-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for the Autoinhibition of Focal Adhesion Kinase. Cell(Cambridge,Mass.), 129, 2007
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2ITT
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![BU of 2itt by Molmil](/molmil-images/mine/2itt) | Crystal structure of EGFR kinase domain L858R mutation in complex with AEE788 | Descriptor: | 6-{4-[(4-ETHYLPIPERAZIN-1-YL)METHYL]PHENYL}-N-[(1R)-1-PHENYLETHYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE, EPIDERMAL GROWTH FACTOR RECEPTOR | Authors: | Yun, C.-H, Boggon, T.J, Li, Y, Woo, S, Greulich, H, Meyerson, M, Eck, M.J. | Deposit date: | 2006-05-25 | Release date: | 2007-04-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity Cancer Cell, 11, 2007
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2J0K
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![BU of 2j0k by Molmil](/molmil-images/mine/2j0k) | Crystal structure of a fragment of focal adhesion kinase containing the FERM and kinase domains. | Descriptor: | 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, FOCAL ADHESION KINASE 1 | Authors: | Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J. | Deposit date: | 2006-08-03 | Release date: | 2007-07-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for the Autoinhibition of Focal Adhesion Kinase. Cell(Cambridge,Mass.), 129, 2007
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2J0J
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![BU of 2j0j by Molmil](/molmil-images/mine/2j0j) | Crystal structure of a fragment of focal adhesion kinase containing the FERM and kinase domains. | Descriptor: | 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, FOCAL ADHESION KINASE 1 | Authors: | Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J. | Deposit date: | 2006-08-03 | Release date: | 2007-06-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for the Autoinhibition of Focal Adhesion Kinase Cell(Cambridge,Mass.), 129, 2007
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2ITN
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![BU of 2itn by Molmil](/molmil-images/mine/2itn) | Crystal structure of EGFR kinase domain G719S mutation in complex with AMP-PNP | Descriptor: | EPIDERMAL GROWTH FACTOR RECEPTOR, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Yun, C.-H, Boggon, T.J, Li, Y, Woo, S, Greulich, H, Meyerson, M, Eck, M.J. | Deposit date: | 2006-05-25 | Release date: | 2007-04-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity Cancer Cell, 11, 2007
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2ITQ
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![BU of 2itq by Molmil](/molmil-images/mine/2itq) | Crystal structure of EGFR kinase domain G719S mutation in complex with AFN941 | Descriptor: | 1,2,3,4-Tetrahydrogen Staurosporine, EPIDERMAL GROWTH FACTOR RECEPTOR | Authors: | Yun, C.-H, Boggon, T.J, Li, Y, Woo, S, Greulich, H, Meyerson, M, Eck, M.J. | Deposit date: | 2006-05-25 | Release date: | 2007-04-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity Cancer Cell, 11, 2007
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