4FWI
 
 | | Crystal structure of the nucleotide-binding domain of a dipeptide ABC transporter | | Descriptor: | ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Li, X, Ge, J, Yang, M, Wang, N. | | Deposit date: | 2012-07-01 | | Release date: | 2013-01-30 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.892 Å) | | Cite: | Structure of the nucleotide-binding domain of a dipeptide ABC transporter reveals a novel iron-sulfur cluster-binding domain
Acta Crystallogr.,Sect.D, 69, 2013
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4QRD
 | | Structure of Methionyl-tRNA Synthetase in complex with N-(1H-benzimidazol-2-ylmethyl)-N'-(2,4-dichlorophenyl)-6-(morpholin-4-yl)-1,3,5-triazine-2,4-diamine | | Descriptor: | MAGNESIUM ION, Methionyl-tRNA synthetase, N-(1H-benzimidazol-2-ylmethyl)-N'-(2,4-dichlorophenyl)-6-(morpholin-4-yl)-1,3,5-triazine-2,4-diamine | | Authors: | Li, X, Hilgers, M.T, Stidham, M, Brown-Driver, V, Shaw, K.J, Finn, J. | | Deposit date: | 2014-06-30 | | Release date: | 2015-07-29 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Discovery and SAR of a Novel Series of Pyrimidine Antibacterials Targeting Methionyl-tRNA Synthetase
to be published
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4QUV
 | | Structure of an integral membrane delta(14)-sterol reductase | | Descriptor: | Delta(14)-sterol reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Li, X, Blobel, G. | | Deposit date: | 2014-07-12 | | Release date: | 2014-10-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.743 Å) | | Cite: | Structure of an integral membrane sterol reductase from Methylomicrobium alcaliphilum.
Nature, 517, 2015
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7WJQ
 | | Crystal structure of GSDMB in complex with Ipah7.8 | | Descriptor: | Isoform 2 of Gasdermin-B, Probable E3 ubiquitin-protein ligase ipaH7.8 | | Authors: | Li, X, Zhang, H, Yin, H. | | Deposit date: | 2022-01-07 | | Release date: | 2023-01-11 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Insights into the GSDMB-mediated cellular lysis and its targeting by IpaH7.8
Nat Commun, 14, 2023
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4JPB
 | | The structure of a ternary complex between CheA domains P4 and P5 with CheW and with an unzipped fragment of TM14, a chemoreceptor analog from Thermotoga maritima. | | Descriptor: | Chemotaxis protein CheA, Chemotaxis protein CheW, Methyl-accepting chemotaxis protein | | Authors: | Li, X, Bayas, C, Bilwes, A.M, Crane, B.R. | | Deposit date: | 2013-03-19 | | Release date: | 2013-08-28 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.186 Å) | | Cite: | The 3.2 angstrom resolution structure of a receptor: CheA:CheW signaling complex defines overlapping binding sites and key residue interactions within bacterial chemosensory arrays.
Biochemistry, 52, 2013
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2M9H
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5X5S
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4KMP
 | | Structure of XIAP-BIR3 and inhibitor | | Descriptor: | (2S,2'S)-N,N'-[(6,6'-difluoro-1H,1'H-2,2'-biindole-3,3'-diyl)bis{methanediyl[(2R,4S)-4-hydroxypyrrolidine-2,1-diyl][(2S)-1-oxobutane-1,2-diyl]}]bis[2-(methylamino)propanamide], E3 ubiquitin-protein ligase XIAP, ZINC ION | | Authors: | Li, X, Wang, J, Condon, S.M, Shi, Y. | | Deposit date: | 2013-05-08 | | Release date: | 2014-05-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure of XIAP-BIR3 and inhibitor
To be Published
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4KMN
 | | Structure of cIAP1-BIR3 and inhibitor | | Descriptor: | (2S)-N-{(2R)-1-[(2R,4S)-2-{[6,6'-difluoro-3'-({(2R,4S)-4-hydroxy-1-[(2S)-2-{[(2S)-2-(methylamino)propanoyl]amino}butanoyl]pyrrolidin-2-yl}methyl)-1H,1'H-2,2'-biindol-3-yl]methyl}-4-hydroxypyrrolidin-1-yl]-1-oxobutan-2-yl}-2-(methylamino)propanamide, Baculoviral IAP repeat-containing protein 2, PHOSPHATE ION, ... | | Authors: | Li, X, Wang, J, Condon, S.M, Shi, Y. | | Deposit date: | 2013-05-08 | | Release date: | 2014-05-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.523 Å) | | Cite: | Structure of cIAP1-BIR3 and inhibitor
To be Published
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3B9Y
 | | Crystal structure of the Nitrosomonas europaea Rh protein | | Descriptor: | Ammonium transporter family Rh-like protein, UNKNOWN LIGAND, octyl beta-D-glucopyranoside | | Authors: | Li, X, Jayachandran, S, Nguyen, H.-H.T, Chan, M.K. | | Deposit date: | 2007-11-07 | | Release date: | 2007-12-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure of the Nitrosomonas europaea Rh protein.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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3B9Z
 | | Crystal structure of the Nitrosomonas europaea Rh protein complexed with carbon dioxide | | Descriptor: | Ammonium transporter family Rh-like protein, CARBON DIOXIDE, UNKNOWN LIGAND, ... | | Authors: | Li, X, Jayachandran, S, Nguyen, H.-H.T, Chan, M.K. | | Deposit date: | 2007-11-07 | | Release date: | 2007-12-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure of the Nitrosomonas europaea Rh protein.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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6N7X
 | | S. cerevisiae U1 snRNP | | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, Pre-mRNA-processing factor 39, Protein NAM8, ... | | Authors: | Li, X, Liu, S, Jiang, J, Zhang, L, Espinosa, S, Hill, R.C, Hansen, K.C, Zhou, Z.H, Zhao, R. | | Deposit date: | 2018-11-28 | | Release date: | 2019-07-24 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing.
Nat Commun, 8, 2017
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2FQD
 | | Crystal Structures of E. coli Laccase CueO under different copper binding situations | | Descriptor: | Blue copper oxidase cueO, CITRIC ACID, COPPER (II) ION, ... | | Authors: | Li, X, Wei, Z, Zhang, M, Teng, M, Gong, W. | | Deposit date: | 2006-01-18 | | Release date: | 2007-01-30 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structures of E. coli laccase CueO at different copper concentrations.
Biochem.Biophys.Res.Commun., 354, 2007
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9F3E
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8HPE
 | | Crystal structure of Leucine dehydrogenase | | Descriptor: | GLYCEROL, Leucine dehydrogenase, SULFATE ION | | Authors: | Li, X, Song, W. | | Deposit date: | 2022-12-12 | | Release date: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.22 Å) | | Cite: | A Tri-Enzyme Cascade for Efficient Production of L-2-Aminobutyrate from L-Threonine.
Chembiochem, 24, 2023
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5WNF
 | | X-RAY CO-STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE (ROCK1) WITH A HIGHLY SELECTIVE INHIBITOR | | Descriptor: | 1-(4-amino-1,2,5-oxadiazol-3-yl)-5-methyl-N-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)-1H-1,2,3-triazole-4-carboxamide, GLYCEROL, Rho-associated protein kinase 1 | | Authors: | Li, X. | | Deposit date: | 2017-07-31 | | Release date: | 2018-08-01 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Novel mechanism of Rho kinase selectivity: beyond the ATP pocket
To Be Published
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5VQL
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5WNG
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5WNE
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5WNH
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2DC2
 | | Solution Structure of PDZ Domain | | Descriptor: | golgi associated PDZ and coiled-coil motif containing isoform b | | Authors: | Li, X, Wu, J, Shi, Y. | | Deposit date: | 2005-12-20 | | Release date: | 2006-09-26 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of GOPC PDZ domain and its interaction with the C-terminal motif of neuroligin
Protein Sci., 15, 2006
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2FLU
 | | Crystal Structure of the Kelch-Neh2 Complex | | Descriptor: | Kelch-like ECH-associated protein 1, Nrf2 | | Authors: | Li, X, Lo, J, Beamer, L, Hannink, M. | | Deposit date: | 2006-01-06 | | Release date: | 2006-08-15 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling.
Embo J., 25, 2006
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8J45
 | | Crystal structure of a Pichia pastoris-expressed IsPETase variant | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Poly(ethylene terephthalate) hydrolase | | Authors: | Li, X, He, H.L, Long, X, Niu, D, Huang, J.-W, Chen, C.-C, Guo, R.-T. | | Deposit date: | 2023-04-19 | | Release date: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Complete decomposition of poly(ethylene terephthalate) by crude PET hydrolytic enzyme produced in Pichia pastoris
Chem Eng J, 2023
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8HR6
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2GNC
 | | Crystal structure of srGAP1 SH3 domain in the slit-robo signaling pathway | | Descriptor: | SLIT-ROBO Rho GTPase-activating protein 1 | | Authors: | Li, X, Liu, Y, Gao, F, Bartlam, M, Wu, J.Y, Rao, Z. | | Deposit date: | 2006-04-10 | | Release date: | 2006-07-18 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Basis of Robo Proline-rich Motif Recognition by the srGAP1 Src Homology 3 Domain in the Slit-Robo Signaling Pathway
J.Biol.Chem., 281, 2006
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