4HYD
| Structure of a presenilin family intramembrane aspartate protease in C2221 space group | Descriptor: | Putative uncharacterized protein | Authors: | Li, X, Dang, S, Yan, C, Wang, J, Shi, Y. | Deposit date: | 2012-11-13 | Release date: | 2012-12-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structure of a presenilin family intramembrane aspartate protease Nature, 493, 2013
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6A5M
| Crystal structure of Arabidopsis thaliana SUVH6 in complex with SAM, form 2 | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6, S-ADENOSYLMETHIONINE, ... | Authors: | Li, X, Du, J. | Deposit date: | 2018-06-24 | Release date: | 2018-08-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6A5N
| Crystal structure of Arabidopsis thaliana SUVH6 in complex with methylated DNA | Descriptor: | DNA (5'-D(*CP*AP*CP*TP*GP*CP*TP*GP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*GP*AP*GP*TP*AP*CP*TP*(5CM)P*AP*GP*CP*AP*GP*T)-3'), Histone-lysine N-methyltransferase, ... | Authors: | Li, X, Du, J. | Deposit date: | 2018-06-24 | Release date: | 2018-08-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6A5K
| Crystal structure of Arabidopsis thaliana SUVH6 in complex with SAM, form 1 | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6, S-ADENOSYLMETHIONINE, ... | Authors: | Li, X, Du, J. | Deposit date: | 2018-06-24 | Release date: | 2018-08-29 | Last modified: | 2018-09-26 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3SIP
| Crystal structure of drICE and dIAP1-BIR1 complex | Descriptor: | Apoptosis 1 inhibitor, Caspase, ZINC ION | Authors: | Li, X, Wang, J, Shi, Y. | Deposit date: | 2011-06-20 | Release date: | 2011-08-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.496 Å) | Cite: | Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICE. Nat Commun, 2, 2011
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5U73
| Crystal structure of human Niemann-Pick C1 protein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Niemann-Pick C1 protein, ... | Authors: | Li, X, Wang, J, Blobel, G. | Deposit date: | 2016-12-11 | Release date: | 2017-09-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.348 Å) | Cite: | 3.3 angstrom structure of Niemann-Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4DXA
| Co-crystal structure of Rap1 in complex with KRIT1 | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Krev interaction trapped protein 1, MAGNESIUM ION, ... | Authors: | Li, X, Zhang, R, Boggon, T.J. | Deposit date: | 2012-02-27 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural Basis for Small G Protein Effector Interaction of Ras-related Protein 1 (Rap1) and Adaptor Protein Krev Interaction Trapped 1 (KRIT1). J.Biol.Chem., 287, 2012
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5U74
| Structure of human Niemann-Pick C1 protein | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, X. | Deposit date: | 2016-12-11 | Release date: | 2017-10-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.335 Å) | Cite: | 3.3 angstrom structure of Niemann-Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4FWI
| Crystal structure of the nucleotide-binding domain of a dipeptide ABC transporter | Descriptor: | ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Li, X, Ge, J, Yang, M, Wang, N. | Deposit date: | 2012-07-01 | Release date: | 2013-01-30 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.892 Å) | Cite: | Structure of the nucleotide-binding domain of a dipeptide ABC transporter reveals a novel iron-sulfur cluster-binding domain Acta Crystallogr.,Sect.D, 69, 2013
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5VB3
| X-ray structure of nuclear receptor ROR-gammat Ligand Binding Domain + SRC2 peptide | Descriptor: | Nuclear receptor ROR-gamma, SRC2 chimera, SODIUM ION | Authors: | Li, X. | Deposit date: | 2017-03-28 | Release date: | 2017-06-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural studies unravel the active conformation of apo ROR gamma t nuclear receptor and a common inverse agonism of two diverse classes of ROR gamma t inhibitors. J. Biol. Chem., 292, 2017
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5V5L
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5VB6
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3SIQ
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3SIR
| Crystal Structure of drICE | Descriptor: | Caspase | Authors: | Li, X, Wang, J, Shi, Y. | Deposit date: | 2011-06-20 | Release date: | 2011-08-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICE. Nat Commun, 2, 2011
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4EIR
| Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases (PMO-2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, GLYCEROL, ... | Authors: | Li, X, Beeson, W.T, Phillips, C.M, Marletta, M.A, Cate, J.H. | Deposit date: | 2012-04-05 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases. Structure, 20, 2012
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5VB5
| X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with an inverse agonist and SRC2 peptide | Descriptor: | N-[(2R)-3-(4-{[3-(4-chlorophenyl)propanoyl]amino}phenyl)-1-(4-methylpiperidin-1-yl)-1-oxopropan-2-yl]-4-methylpentanamide, Nuclear receptor ROR-gamma, SRC2 chimera, ... | Authors: | Li, X. | Deposit date: | 2017-03-28 | Release date: | 2017-06-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.226 Å) | Cite: | Structural studies unravel the active conformation of apo ROR gamma t nuclear receptor and a common inverse agonism of two diverse classes of ROR gamma t inhibitors. J. Biol. Chem., 292, 2017
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5V5M
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5VB7
| X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with an agonist and SRC2 peptide | Descriptor: | N-methyl-N'-(3-methylbut-2-en-1-yl)-N'-(3-phenoxyphenyl)-N-[trans-4-(pyridin-4-yl)cyclohexyl]urea, Nuclear receptor ROR-gamma, SRC2 chimera, ... | Authors: | Li, X. | Deposit date: | 2017-03-28 | Release date: | 2017-06-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.335 Å) | Cite: | Structural studies unravel the active conformation of apo ROR gamma t nuclear receptor and a common inverse agonism of two diverse classes of ROR gamma t inhibitors. J. Biol. Chem., 292, 2017
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4EIS
| Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases (PMO-3) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, PEROXIDE ION, ... | Authors: | Li, X, Beeson, W.T, Phillips, C.M, Marletta, M.A, Cate, J.H. | Deposit date: | 2012-04-05 | Release date: | 2012-05-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases. Structure, 20, 2012
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5VQK
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3UR1
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4HYG
| Structure of a presenilin family intramembrane aspartate protease in C222 space group | Descriptor: | Putative uncharacterized protein | Authors: | Li, X, Dang, S, Yan, C, Wang, J, Shi, Y. | Deposit date: | 2012-11-13 | Release date: | 2012-12-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.32 Å) | Cite: | Structure of a presenilin family intramembrane aspartate protease Nature, 493, 2013
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4HYC
| Structure of a presenilin family intramembrane aspartate protease in P2 space group | Descriptor: | Putative uncharacterized protein | Authors: | Li, X, Dang, S, Yan, C, Wang, J, Shi, Y. | Deposit date: | 2012-11-13 | Release date: | 2012-12-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.95 Å) | Cite: | Structure of a presenilin family intramembrane aspartate protease Nature, 493, 2013
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3L8J
| Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity | Descriptor: | Programmed cell death protein 10 | Authors: | Li, X, Zhang, R, Zhang, H, He, Y, Ji, W, Min, W, Boggon, T.J. | Deposit date: | 2009-12-31 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity. J.Biol.Chem., 285, 2010
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3L8I
| Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity | Descriptor: | Programmed cell death protein 10 | Authors: | Li, X, Zhang, R, Zhang, H, He, Y, Ji, W, Min, W, Boggon, T.J. | Deposit date: | 2009-12-31 | Release date: | 2010-05-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity. J.Biol.Chem., 285, 2010
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