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5VB3

X-ray structure of nuclear receptor ROR-gammat Ligand Binding Domain + SRC2 peptide

Summary for 5VB3
Entry DOI10.2210/pdb5vb3/pdb
Related5VB5 5VB6 5VB7
DescriptorNuclear receptor ROR-gamma, SRC2 chimera, SODIUM ION (3 entities in total)
Functional Keywordsnuclear receptor, nuclear hormone receptor, transcription
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains1
Total formula weight32465.43
Authors
Li, X. (deposition date: 2017-03-28, release date: 2017-06-07, Last modification date: 2024-03-06)
Primary citationLi, X.,Anderson, M.,Collin, D.,Muegge, I.,Wan, J.,Brennan, D.,Kugler, S.,Terenzio, D.,Kennedy, C.,Lin, S.,Labadia, M.E.,Cook, B.,Hughes, R.,Farrow, N.A.
Structural studies unravel the active conformation of apo ROR gamma t nuclear receptor and a common inverse agonism of two diverse classes of ROR gamma t inhibitors.
J. Biol. Chem., 292:11618-11630, 2017
Cited by
PubMed: 28546429
DOI: 10.1074/jbc.M117.789024
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

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