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PDB: 653 results

5EE9
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Complex structure of OSYCHF1 with GMP-PNP
Descriptor: GLYCEROL, MAGNESIUM ION, Obg-like ATPase 1, ...
Authors:Li, X, Chen, Z.
Deposit date:2015-10-22
Release date:2016-02-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:ATP binding by the P-loop NTPase OsYchF1 (an unconventional G protein) contributes to biotic but not abiotic stress responses
Proc.Natl.Acad.Sci.USA, 113, 2016
5EE1
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Crystal structure of OsYchF1 at pH 7.85
Descriptor: Obg-like ATPase 1
Authors:Li, X, Chen, Z.
Deposit date:2015-10-22
Release date:2016-02-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:ATP binding by the P-loop NTPase OsYchF1 (an unconventional G protein) contributes to biotic but not abiotic stress responses
Proc.Natl.Acad.Sci.USA, 113, 2016
5EE3
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BU of 5ee3 by Molmil
COMPLEX STRUCTURE OF OSYCHF1 WITH AMP-PNP
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Li, X, Chen, Z.
Deposit date:2015-10-22
Release date:2016-02-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:ATP binding by the P-loop NTPase OsYchF1 (an unconventional G protein) contributes to biotic but not abiotic stress responses
Proc.Natl.Acad.Sci.USA, 113, 2016
5EE0
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Crystal structure of OsYchF1 at pH 6.5
Descriptor: Obg-like ATPase 1
Authors:Li, X, Chen, Z.
Deposit date:2015-10-22
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:ATP binding by the P-loop NTPase OsYchF1 (an unconventional G protein) contributes to biotic but not abiotic stress responses
Proc.Natl.Acad.Sci.USA, 113, 2016
5VQL
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BU of 5vql by Molmil
X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with a inverse agonist and SRC2 peptide
Descriptor: 5'-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-N-{[4-(ethylsulfonyl)phenyl]methyl}spiro[cyclopentane-1,3'-pyrrolo[3,2-b]pyridine]-1'(2'H)-carboxamide, Nuclear receptor ROR-gamma, SRC2 chimera, ...
Authors:Li, X.
Deposit date:2017-05-09
Release date:2018-05-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with a inverse agonist and SRC2 peptide
To Be Published
7T6B
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BU of 7t6b by Molmil
Structure of S1PR2-heterotrimeric G13 signaling complex
Descriptor: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Li, X, Chen, H.
Deposit date:2021-12-13
Release date:2022-04-06
Last modified:2022-06-29
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structure of S1PR2-heterotrimeric G 13 signaling complex.
Sci Adv, 8, 2022
3NDM
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BU of 3ndm by Molmil
Crystal structure of Rho-Associated Protein Kinase (ROCK1) with a potent isoquinolone derivative
Descriptor: (3S,4R)-N-(7-chloro-1-oxo-1,4-dihydroisoquinolin-6-yl)-4-(4-chlorophenyl)pyrrolidine-3-carboxamide, Rho-Associated Protein Kinase (ROCK1)
Authors:Li, X.
Deposit date:2010-06-07
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 3, aryl substituted pyrrolidines.
Bioorg.Med.Chem.Lett., 20, 2010
4WX0
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BU of 4wx0 by Molmil
UndA complexed with beta-hydroxydodecanoic acid
Descriptor: (3R)-3-HYDROXYDODECANOIC ACID, FE (III) ION, PEROXIDE ION, ...
Authors:Li, X, Cate, J.D.H.
Deposit date:2014-11-13
Release date:2014-12-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Microbial biosynthesis of medium-chain 1-alkenes by a nonheme iron oxidase.
Proc.Natl.Acad.Sci.USA, 111, 2014
2XCN
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BU of 2xcn by Molmil
Crystal structure of HCV NS3 protease with a boronate inhibitor
Descriptor: MAGNESIUM ION, N-[(CYCLOPENTYLOXY)CARBONYL]-3-METHYL-L-VALYL-(4R)-N-{(1R)-3-HYDROXY-1-[HYDROXY(OXIDO)BORANYL]PROPYL}-4-(ISOQUINOLIN-1-YLOXY)-L-PROLINAMIDE, NS3 PROTEASE, ...
Authors:Li, X, Zhang, Y.-K, Liu, Y, Ding, C.Z, Li, Q, Zhou, Y, Plattner, J.J, Baker, S.J, Qian, X, Fan, D, Liao, L, Ni, Z.-J, White, G.V, Mordaunt, J.E, Lazarides, L.X, Slater, M.J, Jarvest, R.L, Thommes, P, Ellis, M, Edge, C.M, Hubbard, J.A, Nassau, P, McDowell, B, Skarzynski, T.J, Rowland, P, Somers, D.O, Kazmierski, W.M, Grimes, R.M, Wright, L.L, Smith, G.K, Zou, W, Wright, J, Pennicott, L.E.
Deposit date:2010-04-23
Release date:2010-06-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Synthesis and Evaluation of Novel Alpha-Amino Cyclic Boronates as Inhibitors of Hcv Ns3 Protease.
Bioorg.Med.Chem.Lett., 20, 2010
2XCF
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BU of 2xcf by Molmil
Crystal structure of HCV NS3 protease with a boronate inhibitor
Descriptor: CYCLOPENTYL N-[(2S)-1-[(2S,4R)-2-[[(4R)-8-HYDROXY-1,6,10-TRIOXA-5$L^{4}-BORASPIRO[4.5]DECAN-4-YL]CARBAMOYL]-4-ISOQUINOLIN-1-YLOXY-PYRROLIDIN-1-YL]-3,3-DIMETHYL-1-OXO-BUTAN-2-YL]CARBAMATE, MAGNESIUM ION, NS3 PROTEASE, ...
Authors:Li, X, Zhang, Y.-K, Liu, Y, Ding, C.Z, Li, Q, Zhou, Y, Plattner, J.J, Baker, S.J, Qian, X, Fan, D, Liao, L, Ni, Z.-J, White, G.V, Mordaunt, J.E, Lazarides, L.X, Slater, M.J, Jarvest, R.L, Thommes, P, Ellis, M, Edge, C.M, Hubbard, J.A, Nassau, P, McDowell, B, Skarzynski, T.J, Rowland, P, Somers, D.O, Kazmierski, W.M, Grimes, R.M, Wright, L.L, Smith, G.K, Zou, W, Wright, J, Pennicott, L.E.
Deposit date:2010-04-22
Release date:2010-06-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Synthesis and Evaluation of Novel Alpha-Amino Cyclic Boronates as Inhibitors of Hcv Ns3 Protease.
Bioorg.Med.Chem.Lett., 20, 2010
2XNI
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Protein-ligand complex of a novel macrocyclic HCV NS3 protease inhibitor derived from amino cyclic boronates
Descriptor: (1-{[(10-tert-butyl-15,15-dimethyl-3,9,12-trioxo-6,7,9,10,11,12,14,15,16,17,18,19,23,23a-tetradecahydro-1H,5H-2,23:5,8-dimethano-4,13,2,8,11-benzodioxatriazacyclohenicosin-7(3H)-yl)carbonyl]amino}-3-hydroxypropyl)(trihydroxy)borate(1-), MAGNESIUM ION, NS3 PROTEASE, ...
Authors:Li, X, Zhang, Y.-K, Liu, Y, Ding, C.Z, Zhou, Y, Li, Q, Plattner, J.J, Baker, S.J, Zhang, S, Kazmierski, W.M, Wright, L.L, Smith, G.K, Grimes, R.M, Crosby, R.M, Creech, K.L, Carballo, L.H, Slater, M.J, Jarvest, R.L, Thommes, P, Hubbard, J.A, Convery, M.A, Nassau, P.M, McDowell, W, Skarzynski, T.J, Qian, X, Fan, D, Liao, L, Ni, Z.-J, Pennicott, L.E, Zou, W, Wright, J.
Deposit date:2010-08-02
Release date:2011-08-17
Last modified:2012-09-26
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Novel Macrocyclic Hcv Ns3 Protease Inhibitors Derived from Alpha-Amino Cyclic Boronates.
Bioorg.Med.Chem.Lett., 20, 2010
4WCW
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BU of 4wcw by Molmil
Ribosomal silencing factor during starvation or stationary phase (RsfS) from Mycobacterium tuberculosis
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, Ribosomal silencing factor RsfS
Authors:Li, X, Sun, Q, Jiang, C, Yang, K, Hung, L, Zhang, J, Sacchettini, J, TB Structural Genomics Consortium (TBSGC)
Deposit date:2014-09-05
Release date:2014-09-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of Ribosomal Silencing Factor Bound to Mycobacterium tuberculosis Ribosome.
Structure, 23, 2015
3NCZ
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BU of 3ncz by Molmil
X-Ray Co-structure of Rho-Associated Protein Kinase (ROCK1) with a potent 2H-isoquinolin-1-one inhibitor
Descriptor: Rho-associated protein kinase 1, cis-4-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)cyclohexanecarboxamide
Authors:Li, X.
Deposit date:2010-06-06
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: Part 2, optimization for blood pressure reduction in spontaneously hypertensive rats.
Bioorg.Med.Chem.Lett., 20, 2010
8HPE
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BU of 8hpe by Molmil
Crystal structure of Leucine dehydrogenase
Descriptor: GLYCEROL, Leucine dehydrogenase, SULFATE ION
Authors:Li, X, Song, W.
Deposit date:2022-12-12
Release date:2024-03-20
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:A Tri-Enzyme Cascade for Efficient Production of L-2-Aminobutyrate from L-Threonine.
Chembiochem, 24, 2023
8XSX
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BU of 8xsx by Molmil
Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Li, X, Wang, M, Cheng, J.
Deposit date:2024-01-10
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8XSZ
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BU of 8xsz by Molmil
Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Li, X, Wang, M, Cheng, J.
Deposit date:2024-01-10
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8XSY
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BU of 8xsy by Molmil
Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled)
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Li, X, Wang, M, Cheng, J.
Deposit date:2024-01-10
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8YOP
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BU of 8yop by Molmil
Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Li, X, Wang, M, Denk, T, Cheng, J.
Deposit date:2024-03-13
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8XT1
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BU of 8xt1 by Molmil
Cryo-EM structure of the human 39S mitoribosome with 5uM Tigecycline
Descriptor: 16s rRNA, 39S ribosomal protein L22, mitochondrial, ...
Authors:Li, X, Wang, M, Cheng, J.
Deposit date:2024-01-10
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8XT3
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BU of 8xt3 by Molmil
Cryo-EM structure of the human 39S mitoribosome with 10uM Tigecycline
Descriptor: 16s rRNA, 39S ribosomal protein L22, mitochondrial, ...
Authors:Li, X, Wang, M, Cheng, J.
Deposit date:2024-01-10
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8XT0
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BU of 8xt0 by Molmil
Cryo-EM structure of the human 55S mitoribosome with 5um Tigecycline
Descriptor: 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ...
Authors:Li, X, Wang, M, Cheng, J.
Deposit date:2024-01-10
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8XT2
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BU of 8xt2 by Molmil
Cryo-EM structure of the human 55S mitoribosome with 10uM Tigecycline
Descriptor: 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ...
Authors:Li, X, Wang, M, Cheng, J.
Deposit date:2024-01-10
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8YOO
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BU of 8yoo by Molmil
Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Li, X, Wang, M, Denk, T, Cheng, J.
Deposit date:2024-03-13
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
3PWU
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BU of 3pwu by Molmil
An immmunodominant CTL epitope from rinderpest virus presented by cattle MHC class I molecule N*01801(BoLA-A11)
Descriptor: Beta-2-microglobulin, IPA from Hemagglutinin glycoprotein, MHC class I antigen
Authors:Li, X, Liu, J, Qi, J, Gao, F, Li, Q, Li, X, Zhang, N, Xia, C, Gao, G.F.
Deposit date:2010-12-09
Release date:2011-08-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Two distinct conformations of a rinderpest virus epitope presented by bovine major histocompatibility complex class I N*01801: a host strategy to present featured peptides
J.Virol., 85, 2011
3PWV
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BU of 3pwv by Molmil
An immmunodominant CTL epitope from rinderpest virus presented by cattle MHC class I molecule N*01801 (BoLA-A11)
Descriptor: 9-mer peptide from Hemagglutinin, Beta-2-microglobulin, MHC class I antigen
Authors:Li, X, Liu, J, Qi, J, Gao, F, Li, Q, Li, X, Zhang, N, Xia, C, Gao, G.F.
Deposit date:2010-12-09
Release date:2011-08-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.696 Å)
Cite:Two distinct conformations of a rinderpest virus epitope presented by bovine major histocompatibility complex class I N*01801: a host strategy to present featured peptides
J.Virol., 85, 2011

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