7YRI
 
 | |
3VBF
 | | Crystal structure of formaldehyde treated human Enterovirus 71 (space group I23) | | 分子名称: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Genome Polyprotein, ... | | 著者 | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | | 登録日 | 2012-01-02 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
|
|
6IY3
 | | Structure of Snf2-MMTV-A nucleosome complex at shl-2 in ADP state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (147-MER), Histone H2A, ... | | 著者 | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | | 登録日 | 2018-12-12 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | | 主引用文献 | Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
|
|
3VBO
 | | Crystal structure of formaldehyde treated empty human Enterovirus 71 particle (cryo at 100K) | | 分子名称: | Genome Polyprotein, capsid protein VP1, capsid protein VP2, ... | | 著者 | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | | 登録日 | 2012-01-02 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | | 主引用文献 | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
|
|
6P02
 | | Crystal structure of Mtb aspartate decarboxylase, 6-Chlorine pyrazinoic acid complex | | 分子名称: | 6-chloropyrazine-2-carboxylic acid, Aspartate 1-decarboxylase alpha chain, Aspartate 1-decarboxylase beta chain | | 著者 | Sun, Q, Li, X, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2019-05-16 | | 公開日 | 2020-02-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD.
Nat Commun, 11, 2020
|
|
6IY2
 | | Structure of Snf2-MMTV-A nucleosome complex at shl2 in ADP state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (147-MER), DNA (167-MER), ... | | 著者 | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | | 登録日 | 2018-12-12 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
|
|
4Q2V
 | | Crystal Structure of Ricin A chain complexed with Baicalin inhibitor | | 分子名称: | 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, Ricin | | 著者 | Deng, X, Li, X, Dong, J, Chen, Y. | | 登録日 | 2014-04-10 | | 公開日 | 2015-04-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | | 主引用文献 | Baicalin inhibits the lethality of ricin in mice by inducing protein oligomerization.
J.Biol.Chem., 290, 2015
|
|
6AYE
 | | Human apo-TRPML3 channel at pH 7.4 | | 分子名称: | Mucolipin-3 | | 著者 | Zhou, X, Li, M, Su, D, Jia, Q, Li, H, Li, X, Yang, J. | | 登録日 | 2017-09-08 | | 公開日 | 2017-11-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.06 Å) | | 主引用文献 | Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states.
Nat. Struct. Mol. Biol., 24, 2017
|
|
6GQJ
 | | Crystal structure of human c-KIT kinase domain in complex with AZD3229-analogue (compound 18) | | 分子名称: | 2-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxy-phenyl]-~{N}-(1-propan-2-ylpyrazol-4-yl)ethanamide, Mast/stem cell growth factor receptor Kit | | 著者 | Schimpl, M, Hardy, C.J, Ogg, D.J, Overman, R.C, Packer, M.J, Kettle, J.G, Anjum, R, Barry, E, Bhavsar, D, Brown, C, Campbell, A, Goldberg, K, Grondine, M, Guichard, S, Hunt, T, Jones, O, Li, X, Moleva, O, Pearson, S, Shao, W, Smith, A, Smith, J, Stead, D, Stokes, S, Tucker, M, Ye, Y. | | 登録日 | 2018-06-07 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors.
J. Med. Chem., 61, 2018
|
|
6GQO
 | | Crystal structure of human KDR (VEGFR2) kinase domain in complex with AZD3229-analogue (compound 18) | | 分子名称: | 2-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxy-phenyl]-~{N}-(1-propan-2-ylpyrazol-4-yl)ethanamide, Vascular endothelial growth factor receptor 2 | | 著者 | Ogg, D.J, Schimpl, M, Hardy, C.J, Overman, R.C, Packer, M.J, Kettle, J.G, Anjum, R, Barry, E, Bhavsar, D, Brown, C, Campbell, A, Goldberg, K, Grondine, M, Guichard, S, Hunt, T, Jones, O, Li, X, Moleva, O, Pearson, S, Shao, W, Smith, A, Smith, J, Stead, D, Stokes, S, Tucker, M, Ye, Y. | | 登録日 | 2018-06-07 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors.
J. Med. Chem., 61, 2018
|
|
6GQK
 | | Crystal structure of human c-KIT kinase domain in complex with AZD3229-analogue (compound 23) | | 分子名称: | Mast/stem cell growth factor receptor Kit, ~{N}-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-2-(1-ethylpyrazol-4-yl)ethanamide | | 著者 | Schimpl, M, Hardy, C.J, Ogg, D.J, Overman, R.C, Packer, M.J, Kettle, J.G, Anjum, R, Barry, E, Bhavsar, D, Brown, C, Campbell, A, Goldberg, K, Grondine, M, Guichard, S, Hunt, T, Jones, O, Li, X, Moleva, O, Pearson, S, Shao, W, Smith, A, Smith, J, Stead, D, Stokes, S, Tucker, M, Ye, Y. | | 登録日 | 2018-06-07 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors.
J. Med. Chem., 61, 2018
|
|
3E6U
 | | Crystal structure of Human LanCL1 | | 分子名称: | LanC-like protein 1, ZINC ION | | 著者 | Zhang, W, Zhu, G, Li, X, Rao, Z, Zhang, C. | | 登録日 | 2008-08-16 | | 公開日 | 2009-06-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione
Genes Dev., 23, 2009
|
|
6LH8
 | | Structure of aerolysin-like protein (Bombina maxima) | | 分子名称: | aerolysin-like protein | | 著者 | Bian, X.L, Wang, Q.Q, Li, X, Teng, M.Q, Zhang, Y. | | 登録日 | 2019-12-07 | | 公開日 | 2020-06-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.729 Å) | | 主引用文献 | A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions.
J.Biol.Chem., 295, 2020
|
|
6LHZ
 | | Structure of aerolysin-like protein (Bombina maxima) | | 分子名称: | aerolysin-like protein | | 著者 | Bian, X.L, Wang, Q.Q, Li, X, Teng, M.Q, Zhang, Y. | | 登録日 | 2019-12-10 | | 公開日 | 2020-06-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions.
J.Biol.Chem., 295, 2020
|
|
7YLT
 | |
3EQT
 | |
6J60
 | | hnRNP A1 reversible amyloid core GFGGNDNFG (residues 209-217) | | 分子名称: | 9-mer peptide (GFGGNDNFG) from Heterogeneous nuclear ribonucleoprotein A1 | | 著者 | Luo, F, Zhou, H, Gui, X, Li, D, Li, X, Liu, C. | | 登録日 | 2019-01-12 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (0.96 Å) | | 主引用文献 | Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly.
Nat Commun, 10, 2019
|
|
8SDE
 | |
8CUF
 | | Synthetic epi-Novo29 (2R,3S), X-ray diffractometer structure | | 分子名称: | ACETATE ION, IODIDE ION, Synthetic epi-Novo29 (2R,3S) | | 著者 | Kreutzer, A.G, Li, X, Krumberger, M, Nowick, J.S. | | 登録日 | 2022-05-17 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Synthesis and Stereochemical Determination of the Peptide Antibiotic Novo29.
J.Org.Chem., 88, 2023
|
|
6AYF
 | | TRPML3/ML-SA1 complex at pH 7.4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-3 | | 著者 | Zhou, X, Li, M, Su, D, Jia, Q, Li, H, Li, X, Yang, J. | | 登録日 | 2017-09-08 | | 公開日 | 2017-11-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states.
Nat. Struct. Mol. Biol., 24, 2017
|
|
8T05
 | | Structure of Ciona Myomaker bound to Fab1A1 | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1A1 Fab heavy chain, 1A1 Fab light chain, ... | | 著者 | Long, T, Li, X. | | 登録日 | 2023-05-31 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
|
|
8T03
 | | Structure of mouse Myomaker bound to Fab18G7 in detergent | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 18G7 Fab heavy chain, 18G7 Fab light chain, ... | | 著者 | Long, T, Li, X. | | 登録日 | 2023-05-31 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
|
|
8T07
 | |
8T04
 | | Structure of mouse Myomaker bound to Fab18G7 in nanodiscs | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 18G7 Fab heavy chain, 18G7 Fab light chain, ... | | 著者 | Long, T, Li, X. | | 登録日 | 2023-05-31 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | | 主引用文献 | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
|
|
8T06
 | |
