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PDB: 157 件

3LRR
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Crystal structure of human RIG-I CTD bound to a 12 bp AU rich 5' ppp dsRNA
分子名称: Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(ATP)P*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*U)-3'), ZINC ION
著者Li, P.
登録日2010-02-11
公開日2010-06-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
Structure, 18, 2010
7OP3
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BU of 7op3 by Molmil
Cryo-EM structure of P5B-ATPase E2PiSPM
分子名称: Cation-transporting ATPase, SPERMINE
著者Li, P, Gronberg, C, Wang, K.T, Salustros, N, Gourdon, P.E.
登録日2021-05-28
公開日2021-06-30
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
1J4H
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BU of 1j4h by Molmil
crystal structure analysis of the FKBP12 complexed with 000107 small molecule
分子名称: 3-PHENYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PROPIONIC ACID ETHYL ESTER, FKBP12
著者Li, P, Ding, Y, Wang, L, Wu, B, Shu, C, Li, S, Shen, B, Rao, Z.
登録日2001-09-30
公開日2003-06-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design and structure-based study of new potential FKBP12 inhibitors.
Biophys.J., 85, 2003
1J4I
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crystal structure analysis of the FKBP12 complexed with 000308 small molecule
分子名称: 4-METHYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PENTANOIC ACID, FKBP12
著者Li, P, Ding, Y, Wang, L, Wu, B, Shu, C, Li, S, Shen, B, Rao, Z.
登録日2001-09-30
公開日2003-06-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design and structure-based study of new potential FKBP12 inhibitors.
Biophys.J., 85, 2003
7OP1
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Cryo-EM structure of P5B-ATPase E2PiAlF/SPM
分子名称: Cation-transporting ATPase, MAGNESIUM ION, SPERMINE, ...
著者Li, P, Gourdon, P.
登録日2021-05-28
公開日2021-06-30
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
7OP8
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BU of 7op8 by Molmil
Cryo-EM structure of P5B-ATPase E2Pinhibit
分子名称: BERYLLIUM TRIFLUORIDE ION, Cation-transporting ATPase, MAGNESIUM ION
著者Li, P, Gourdon, P.
登録日2021-05-31
公開日2021-06-30
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
7OP5
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BU of 7op5 by Molmil
Cryo-EM structure of P5B-ATPase E2P
分子名称: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, P5B-ATPase
著者Li, P, Gourdon, P.
登録日2021-05-29
公開日2021-06-30
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
7PGE
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BU of 7pge by Molmil
copper transporter PcoB
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Copper resistance protein B, LAURYL DIMETHYLAMINE-N-OXIDE, ...
著者Li, P, Gourdon, P.E.
登録日2021-08-13
公開日2022-07-06
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献PcoB is a defense outer membrane protein that facilitates cellular uptake of copper.
Protein Sci., 31, 2022
7PRO
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BU of 7pro by Molmil
Structure of CtAtm1 in the inward-open with Glutathione-complexed [2Fe-2S] cluster bound
分子名称: Putative iron-sulfur protein
著者Li, P, Wang, K.T, Gourdon, P.E.
登録日2021-09-22
公開日2022-08-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.
Nat Commun, 13, 2022
7PR1
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BU of 7pr1 by Molmil
Structure of CtAtm1 in the occluded conformation with ATP bound
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative iron-sulfur protein
著者Li, P, Wang, K.T, Gourdon, P.E.
登録日2021-09-20
公開日2022-08-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.
Nat Commun, 13, 2022
7PRU
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BU of 7pru by Molmil
Structure of CtAtm1 in the inward-facing partially occluded with cargo bound
分子名称: GLUTATHIONE, Putative iron-sulfur protein
著者Li, P, Wang, K.T, Gourdon, P.E.
登録日2021-09-22
公開日2022-08-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.
Nat Commun, 13, 2022
7PQX
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BU of 7pqx by Molmil
Structure of CtAtm1 in the inward-facing open conformation
分子名称: Putative iron-sulfur protein
著者Li, P, Wang, K.T, Gourdon, P.E.
登録日2021-09-20
公開日2022-08-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.
Nat Commun, 13, 2022
7PSD
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BU of 7psd by Molmil
Structure of CtAtm1(E603Q) in the inward-facing open conformation
分子名称: Putative iron-sulfur protein
著者Li, P, Wang, K.T, Gourdon, P.E.
登録日2021-09-22
公開日2022-08-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.
Nat Commun, 13, 2022
5HNV
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BU of 5hnv by Molmil
Crystal structure of PpkA
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Li, P.P, Ran, T.T, Wang, W.W.
登録日2016-01-19
公開日2017-01-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Crystal structures of the kinase domain of PpkA, a key regulatory component of T6SS, reveal a general inhibitory mechanism.
Biochem.J., 475, 2018
6O8C
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BU of 6o8c by Molmil
Crystal structure of STING CTT in complex with TBK1
分子名称: N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein
著者Li, P, Zhao, B, Du, F.
登録日2019-03-09
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature, 569, 2019
6O8B
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Crystal structure of STING CTD in complex with TBK1
分子名称: N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein
著者Li, P, Zhao, B, Du, F.
登録日2019-03-09
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature, 569, 2019
4Q05
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BU of 4q05 by Molmil
Crystal structure of an esterase E25
分子名称: SODIUM ION, esterase E25
著者Li, P.Y, Li, C.Y, Zhang, Y.Z.
登録日2014-03-31
公開日2014-06-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for dimerization and catalysis of a novel esterase from the GTSAG motif subfamily of the bacterial hormone-sensitive lipase family
J.Biol.Chem., 289, 2014
2GSG
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BU of 2gsg by Molmil
Crystal structure of the Fv fragment of a monoclonal antibody specific for poly-glutamine
分子名称: SULFATE ION, monoclonal antibody heavy chain, monoclonal antibody light chain
著者Li, P, Huey-Tubman, K.E, West Jr, A.P, Bennett, M.J, Bjorkman, P.J.
登録日2006-04-26
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of a polyQ-anti-polyQ complex reveals binding according to a linear lattice model.
Nat.Struct.Mol.Biol., 14, 2007
1HYR
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BU of 1hyr by Molmil
CRYSTAL STRUCTURE OF HUMAN MICA IN COMPLEX WITH NATURAL KILLER CELL RECEPTOR NKG2D
分子名称: MHC CLASS I CHAIN-RELATED PROTEIN A, NKG2-D TYPE II INTEGRAL MEMBRANE PROTEIN
著者Li, P, Strong, R.K.
登録日2001-01-21
公開日2001-05-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA.
Nat.Immunol., 2, 2001
3EQT
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BU of 3eqt by Molmil
Crystal structure of human LGP2 C-terminal domain in complex with dsRNA
分子名称: 5'-R(*GP*CP*GP*CP*GP*CP*GP*C)-3', ATP-dependent RNA helicase DHX58, ZINC ION
著者Li, P, Li, X.
登録日2008-10-01
公開日2009-03-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The RIG-I-like Receptor LGP2 Recognizes the Termini of Double-stranded RNA
J.Biol.Chem., 284, 2009
6LKA
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BU of 6lka by Molmil
Crystal Structure of EV71-3C protease with a Novel Macrocyclic Compounds
分子名称: 3C proteinase, ~{N}-[(2~{S})-1-[[(2~{S},3~{S},6~{S},7~{Z},12~{E})-4,9-bis(oxidanylidene)-6-[[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]methyl]-2-phenyl-1,10-dioxa-5-azacyclopentadeca-7,12-dien-3-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide
著者Li, P, Wu, S.Q, Xiao, T.Y.C, Li, Y.L, Su, Z.M, Hao, F, Hu, G.P, Hu, J, Lin, F.S, Chen, X.S, Gu, Z.X, He, H.Y, Li, J, Chen, S.H.
登録日2019-12-18
公開日2020-06-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.033 Å)
主引用文献Design, synthesis, and evaluation of a novel macrocyclic anti-EV71 agent.
Bioorg.Med.Chem., 28, 2020
6J76
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Structure of 3,6-anhydro-L-galactose Dehydrogenase in Complex with NAP
分子名称: Aldehyde dehydrogenase A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Li, P.Y, Wang, Y, Chen, X.L, Zhang, Y.Z.
登録日2019-01-17
公開日2020-01-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.368 Å)
主引用文献3,6-Anhydro-L-Galactose Dehydrogenase VvAHGD is a Member of a New Aldehyde Dehydrogenase Family and Catalyzes by a Novel Mechanism with Conformational Switch of Two Catalytic Residues Cysteine 282 and Glutamate 248.
J.Mol.Biol., 432, 2020
4LEZ
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BU of 4lez by Molmil
Structure of mouse cGAS bound to an 18bp DNA and cGAS product
分子名称: 18bp dsDNA, Cyclic GMP-AMP synthase, ZINC ION, ...
著者Li, P.
登録日2013-06-26
公開日2013-12-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization.
Immunity, 39, 2013
1B3J
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STRUCTURE OF THE MHC CLASS I HOMOLOG MIC-A, A GAMMADELTA T CELL LIGAND
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS I HOMOLOG MIC-A
著者Li, P, Willie, S, Bauer, S, Morris, D, Spies, T, Strong, R.
登録日1998-12-11
公開日1999-07-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the MHC class I homolog MIC-A, a gammadelta T cell ligand.
Immunity, 10, 1999
6J75
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Structure of 3,6-anhydro-L-galactose Dehydrogenase
分子名称: Aldehyde dehydrogenase A
著者Li, P.Y, Wang, Y, Chen, X.L, Zhang, Y.Z.
登録日2019-01-17
公開日2020-01-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.695 Å)
主引用文献3,6-Anhydro-L-Galactose Dehydrogenase VvAHGD is a Member of a New Aldehyde Dehydrogenase Family and Catalyzes by a Novel Mechanism with Conformational Switch of Two Catalytic Residues Cysteine 282 and Glutamate 248.
J.Mol.Biol., 432, 2020

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