6DWU
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5H3O
| Structure of a eukaryotic cyclic nucleotide-gated channel | Descriptor: | CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel, SODIUM ION | Authors: | Li, M, Zhou, X, Wang, S, Michailidis, I, Gong, Y, Su, D, Li, H, Li, X, Yang, J. | Deposit date: | 2016-10-26 | Release date: | 2017-01-25 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of a eukaryotic cyclic-nucleotide-gated channel. Nature, 542, 2017
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8K96
| CryoEM structure of LonC protease hepatmer with Bortezomib | Descriptor: | N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, PHOSPHATE ION, endopeptidase La | Authors: | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | Deposit date: | 2023-07-31 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K93
| CryoEM structure of LonC protease S582A open hexamer with lysozyme | Descriptor: | Endopeptidase La, Monothiophosphate | Authors: | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | Deposit date: | 2023-07-31 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K97
| CryoEM structure of LonC protease hexamer with Bortezomib | Descriptor: | N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, PHOSPHATE ION, endopeptidase La | Authors: | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | Deposit date: | 2023-07-31 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K8Y
| CryoEM structure of LonC heptamer in presence of AGS | Descriptor: | Monothiophosphate, endopeptidase La | Authors: | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | Deposit date: | 2023-07-31 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K8X
| CryoEM of LonC open pentamer, apo state | Descriptor: | endopeptidase La | Authors: | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | Deposit date: | 2023-07-31 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K92
| CryoEM structure of LonC S582A hexamer with Lysozyme | Descriptor: | Endopeptidase La, Monothiophosphate | Authors: | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | Deposit date: | 2023-07-31 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.31 Å) | Cite: | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K8V
| CryoEM structure of LonC protease hepatmer, apo state | Descriptor: | PHOSPHATE ION, endopeptidase La | Authors: | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | Deposit date: | 2023-07-31 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K95
| CryoEM structure of LonC protease open Hexamer, AGS | Descriptor: | Monothiophosphate, endopeptidase La | Authors: | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | Deposit date: | 2023-07-31 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K90
| CryoEM structure of LonC protease open pentamer in presence of AGS | Descriptor: | Monothiophosphate, endopeptidase La | Authors: | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | Deposit date: | 2023-07-31 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K91
| CryoEM structure of LonC S582A hepatmer with Lysozyme | Descriptor: | Endopeptidase La, Monothiophosphate | Authors: | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | Deposit date: | 2023-07-31 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K8Z
| CryoEM structure of LonC protease hexamer in presence of AGS | Descriptor: | Monothiophosphate, endopeptidase La | Authors: | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | Deposit date: | 2023-07-31 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K8W
| CryoEM structure of LonC protease open hexamer, apo state | Descriptor: | endopeptidase La | Authors: | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | Deposit date: | 2023-07-31 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K94
| CryoEM structure of LonC protease S582A open pentamer with lysozyme | Descriptor: | Endopeptidase La, Monothiophosphate | Authors: | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | Deposit date: | 2023-07-31 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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3LJC
| Crystal structure of Lon N-terminal domain. | Descriptor: | ATP-dependent protease La | Authors: | Li, M, Gustchina, A, Dauter, Z, Wlodawer, A. | Deposit date: | 2010-01-26 | Release date: | 2010-07-21 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the N-terminal fragment of Escherichia coli Lon protease Acta Crystallogr.,Sect.D, 66, 2010
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6KHX
| Crystal structure of Prx from Akkermansia muciniphila | Descriptor: | CALCIUM ION, Peroxiredoxin | Authors: | Li, M, Wang, J, Xu, W, Wang, Y, Zhang, M, Wang, M. | Deposit date: | 2019-07-16 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Crystal structure of Akkermansia muciniphila peroxiredoxin reveals a novel regulatory mechanism of typical 2-Cys Prxs by a distinct loop. Febs Lett., 594, 2020
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1AER
| DOMAIN III OF PSEUDOMONAS AERUGINOSA EXOTOXIN COMPLEXED WITH BETA-TAD | Descriptor: | 2-(1,5-DIDEOXYRIBOSE)-4-AMIDO-THIAZOLE, ADENOSINE MONOPHOSPHATE, BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, ... | Authors: | Li, M, Dyda, F, Benhar, I, Pastan, I, Davies, D.R. | Deposit date: | 1995-12-11 | Release date: | 1996-06-10 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation Proc.Natl.Acad.Sci.USA, 93, 1996
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5TJA
| I-II linker of TRPML1 channel at pH 6 | Descriptor: | Mucolipin-1 | Authors: | Li, M, Zhang, W.K, Benvin, N.M, Zhou, X, Su, D, Li, H, Wang, S, Michailidis, I.E, Tong, L, Li, X, Yang, J. | Deposit date: | 2016-10-04 | Release date: | 2017-01-25 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel. Nat. Struct. Mol. Biol., 24, 2017
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5TJC
| I-II linker of TRPML1 channel at pH 7.5 | Descriptor: | Mucolipin-1 | Authors: | Li, M, Zhang, W.K, Benvin, N.M, Zhou, X, Su, D, Li, H, Wang, S, Michailidis, I.E, Tong, L, Li, X, Yang, J. | Deposit date: | 2016-10-04 | Release date: | 2017-01-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel. Nat. Struct. Mol. Biol., 24, 2017
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5TJB
| I-II linker of TRPML1 channel at pH 4.5 | Descriptor: | Mucolipin-1 | Authors: | Li, M, Zhang, W.K, Benvin, N.M, Zhou, X, Su, D, Li, H, Wang, S, Michailidis, I.E, Tong, L, Li, X, Yang, J. | Deposit date: | 2016-10-04 | Release date: | 2017-01-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel. Nat. Struct. Mol. Biol., 24, 2017
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6DWH
| Crystal structure of complex of BBKI and Bovine Trypsin | Descriptor: | CHLORIDE ION, Cationic trypsin, Kunitz-type inihibitor, ... | Authors: | Li, M, Wlodawer, A. | Deposit date: | 2018-06-26 | Release date: | 2019-01-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the complex of a kallikrein inhibitor from Bauhinia bauhinioides with trypsin and modeling of kallikrein complexes. Acta Crystallogr D Struct Biol, 75, 2019
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6DWF
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6LI3
| cryo-EM structure of GPR52-miniGs-NB35 | Descriptor: | G-protein coupled receptor 52, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Li, M, Wang, N, Xu, F, Wu, J, Lei, M. | Deposit date: | 2019-12-10 | Release date: | 2020-02-26 | Last modified: | 2020-03-18 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Structural basis of ligand recognition and self-activation of orphan GPR52. Nature, 579, 2020
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7UT3
| Crystal structure of complex of Fab, G10C with GalNAc-pNP | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-nitrophenyl 2-acetamido-2-deoxy-alpha-D-galactopyranoside, Fab protein heavy chain, ... | Authors: | Li, M, Wlodawer, A. | Deposit date: | 2022-04-26 | Release date: | 2022-09-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Development of a GalNAc-Tyrosine-Specific Monoclonal Antibody and Detection of Tyrosine O -GalNAcylation in Numerous Human Tissues and Cell Lines. J.Am.Chem.Soc., 144, 2022
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