5IRO
 
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1Q94
 | | Structures of HLA-A*1101 in complex with immunodominant nonamer and decamer HIV-1 epitopes clearly reveal the presence of a middle anchor residue | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-11 alpha chain, ... | | 著者 | Li, L, McNicholl, J.M, Bouvier, M. | | 登録日 | 2003-08-22 | | 公開日 | 2004-06-01 | | 最終更新日 | 2020-02-05 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of HLA-A*1101 complexed with immunodominant nonamer and decamer HIV-1 epitopes clearly reveal the presence of a middle, secondary anchor residue.
J.Immunol., 172, 2004
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8E13
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8E8I
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8EC5
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8E2Z
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8ELC
 | | Human JNK2 bound to covalent inhibitor YL2056 | | 分子名称: | 4-(dimethylamino)-N-{4-[(3S)-3-({4-[(8R)-2-phenylpyrazolo[1,5-a]pyridin-3-yl]pyrimidin-2-yl}amino)pyrrolidine-1-carbonyl]phenyl}butanamide, Mitogen-activated protein kinase 9 | | 著者 | Li, L, Gurbani, D, Westover, K.D. | | 登録日 | 2022-09-23 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.072 Å) | | 主引用文献 | Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1.
J.Med.Chem., 66, 2023
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7XB0
 | | Crystal structure of Omicron BA.2 RBD complexed with hACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Li, L, Liao, H, Meng, Y, Li, W. | | 登録日 | 2022-03-19 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1.
Cell, 185, 2022
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5DY3
 | | Crystal structure of Dbr2 | | 分子名称: | Artemisinic aldehyde Delta(11(13)) reductase, DI(HYDROXYETHYL)ETHER, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Li, L, Chen, T.T, Xu, Y.C. | | 登録日 | 2015-09-24 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | The Crystal structure of Dbr2
to be published
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5DXY
 | | Crystal structure of Dbr2 | | 分子名称: | Artemisinic aldehyde Delta(11(13)) reductase, FLAVIN MONONUCLEOTIDE, [[(2R,3S,4R,5R)-5-(5-aminocarbonyl-3,4-dihydro-2H-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate | | 著者 | Li, L, Chen, T.T, Xu, Y.C. | | 登録日 | 2015-09-24 | | 公開日 | 2016-10-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | The Crystal structure of Dbr2
to be published
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5DXX
 | | Crystal structure of Dbr2 | | 分子名称: | Artemisinic aldehyde Delta(11(13)) reductase, FLAVIN MONONUCLEOTIDE | | 著者 | Li, L, Chen, T.T, Xu, Y.C. | | 登録日 | 2015-09-24 | | 公開日 | 2016-10-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | The Crystal structure of Dbr2
to be published
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4E5X
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3MUU
 | | Crystal structure of the Sindbis virus E2-E1 heterodimer at low pH | | 分子名称: | Structural polyprotein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Li, L, Jose, J, Xiang, Y, Kuhn, R.J, Rossmann, M.G. | | 登録日 | 2010-05-03 | | 公開日 | 2010-11-24 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.29 Å) | | 主引用文献 | Structural changes of envelope proteins during alphavirus fusion.
Nature, 468, 2010
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3MUW
 | | Pseudo-atomic structure of the E2-E1 protein shell in Sindbis virus | | 分子名称: | Structural polyprotein | | 著者 | Li, L, Jose, J, Xiang, Y, Kuhn, R.J, Rossmann, M.G. | | 登録日 | 2010-05-03 | | 公開日 | 2010-11-24 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Structural changes of envelope proteins during alphavirus fusion.
Nature, 468, 2010
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5EUL
 | | Structure of the SecA-SecY complex with a translocating polypeptide substrate | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, AYC08, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Li, L, Park, E, Ling, J, Ingram, J, Ploegh, H, Rapoport, T.A. | | 登録日 | 2015-11-18 | | 公開日 | 2016-03-09 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Crystal structure of a substrate-engaged SecY protein-translocation channel.
Nature, 531, 2016
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5DY2
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8WMK
 | | Structure of ConA/Man2 | | 分子名称: | 4-[3-(4-carboxyphenyl)phenyl]benzoic acid, CALCIUM ION, Concanavalin-A, ... | | 著者 | Li, L, Chen, G. | | 登録日 | 2023-10-03 | | 公開日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Rational design of inducing ligands with three-dimensional supramolecular interactions to build protein crystalline frameworks.
To Be Published
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8WMG
 | | Structure of ConA/Man3 | | 分子名称: | 4-[3,5-bis(4-carboxyphenyl)phenyl]benzoic acid, CALCIUM ION, Concanavalin-A, ... | | 著者 | Li, L, Chen, G. | | 登録日 | 2023-10-03 | | 公開日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Rational design of inducing ligands with three-dimensional supramolecular interactions to build protein crystalline frameworks.
To Be Published
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2I5N
 | | 1.96 A X-ray structure of photosynthetic reaction center from Rhodopseudomonas viridis:Crystals grown by microfluidic technique | | 分子名称: | 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL B, BACTERIOPHEOPHYTIN B, ... | | 著者 | Li, L, Mustafi, D, Fu, Q, Tereshko, V, Chen, D.L, Tice, J.D, Ismagilov, R.F. | | 登録日 | 2006-08-25 | | 公開日 | 2006-09-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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7N8T
 | | Crystal Structure of AMP-bound Human JNK2 | | 分子名称: | ADENOSINE MONOPHOSPHATE, HEXAETHYLENE GLYCOL, Mitogen-activated protein kinase 9 | | 著者 | Li, L, Gurbani, D, Westover, K.D. | | 登録日 | 2021-06-15 | | 公開日 | 2022-06-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1.
J.Med.Chem., 66, 2023
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2MMF
 | | Solution structure of AGA modified | | 分子名称: | DNA_(5'-D(*CP*TP*AP*AP*(FAG)P*AP*TP*TP*CP*A)-3'), DNA_(5'-D(*TP*GP*AP*AP*TP*CP*TP*TP*AP*G)-3') | | 著者 | Li, L, Stone, M. | | 登録日 | 2014-03-14 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | DNA Sequence Modulates Geometrical Isomerism of the trans-8,9-Dihydro-8-(2,6-diamino-4-oxo-3,4-dihydropyrimid-5-yl-formamido)-9-hydroxy Aflatoxin B1 Adduct.
Chem.Res.Toxicol., 28, 2015
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2MMR
 | | AGC FAPY modified duplex Major isomer | | 分子名称: | DNA_(5'-D(*CP*TP*AP*AP*(FAG)P*CP*TP*TP*CP*A)-3'), DNA_(5'-D(*TP*GP*AP*AP*GP*CP*TP*TP*AP*G)-3') | | 著者 | Li, L, Stone, M. | | 登録日 | 2014-03-17 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | DNA Sequence Modulates Geometrical Isomerism of the trans-8,9-Dihydro-8-(2,6-diamino-4-oxo-3,4-dihydropyrimid-5-yl-formamido)-9-hydroxy Aflatoxin B1 Adduct.
Chem.Res.Toxicol., 28, 2015
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2MMQ
 | | Solution structure of AGT FAPY Modified duplex | | 分子名称: | DNA_(5'-D(*CP*TP*AP*AP*(FAG)P*TP*TP*TP*CP*A)-3'), DNA_(5'-D(*TP*GP*AP*AP*AP*CP*TP*TP*AP*G)-3') | | 著者 | Li, L, Stone, M. | | 登録日 | 2014-03-17 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | DNA Sequence Modulates Geometrical Isomerism of the trans-8,9-Dihydro-8-(2,6-diamino-4-oxo-3,4-dihydropyrimid-5-yl-formamido)-9-hydroxy Aflatoxin B1 Adduct.
Chem.Res.Toxicol., 28, 2015
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2MMS
 | | AG(7-deaza)G FAPY modified duplex | | 分子名称: | DNA_(5'-D(*CP*TP*AP*AP*(FAG)P*(7GU)P*TP*TP*CP*A)-3'), DNA_(5'-D(*TP*GP*AP*AP*CP*CP*TP*TP*AP*G)-3') | | 著者 | Li, L, Stone, M. | | 登録日 | 2014-03-17 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | DNA Sequence Modulates Geometrical Isomerism of the trans-8,9-Dihydro-8-(2,6-diamino-4-oxo-3,4-dihydropyrimid-5-yl-formamido)-9-hydroxy Aflatoxin B1 Adduct.
Chem.Res.Toxicol., 28, 2015
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3IPZ
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