1RLG
 
 | | Molecular basis of Box C/D RNA-protein interaction: co-crystal structure of the Archaeal sRNP intiation complex | | 分子名称: | 25-MER, 50S ribosomal protein L7Ae | | 著者 | Moore, T, Zhang, Y, Fenley, M.O, Li, H. | | 登録日 | 2003-11-25 | | 公開日 | 2004-06-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Molecular Basis of Box C/D RNA-Protein Interactions; Cocrystal Structure of Archaeal L7Ae and a Box C/D RNA.
STRUCTURE, 12, 2004
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3JWT
 | | Structure of rat neuronal nitric oxide synthase R349A mutant heme domain in complex with N1-{(3'R,4'R)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-{(3R,4R)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-[2-(3-fluorophenyl)ethyl]ethane-1,2-diamine, ... | | 著者 | Delker, S.L, Li, H, Poulos, T.L. | | 登録日 | 2009-09-18 | | 公開日 | 2010-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model.
J.Am.Chem.Soc., 132, 2010
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3JX1
 | | Structure of rat neuronal nitric oxide synthase D597N mutant heme domain in complex with N1-{(3'R,4'R)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-{(3R,4R)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-[2-(3-fluorophenyl)ethyl]ethane-1,2-diamine, ... | | 著者 | Delker, S.L, Li, H, Poulos, T.L. | | 登録日 | 2009-09-18 | | 公開日 | 2010-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model.
J.Am.Chem.Soc., 132, 2010
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3JWX
 | | Structure of endothelial nitric oxide synthase heme domain complexed with N1-[(3'R,4'R)-4'-((6"-amino-4"-methylpyridin-2"-yl)methyl)pyrrolidin-3'-yl]-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLIC ACID, ... | | 著者 | Delker, S.L, Li, H, Poulos, T.L. | | 登録日 | 2009-09-18 | | 公開日 | 2010-05-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model.
J.Am.Chem.Soc., 132, 2010
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3JX6
 | | Structure of neuronal nitric oxide synthase D597N/M336V/Y706A mutant heme domain complexed with N1-[(3' R,4' R)-4'-((6"-amino-4"-methylpyridin-2"-yl)methyl)pyrrolidin-3'-yl]-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-{(3R,4R)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-[2-(3-fluorophenyl)ethyl]ethane-1,2-diamine, ... | | 著者 | Delker, S.L, Li, H, Poulos, T.L. | | 登録日 | 2009-09-18 | | 公開日 | 2010-05-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model.
J.Am.Chem.Soc., 132, 2010
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5UN0
 | | Crystal Structure of Mycobacterium Tuberculosis Proteasome-assembly chaperone homologue Rv2125 | | 分子名称: | proteasome assembly chaperone 2 (PAC2) homologue Rv2125 | | 著者 | Bai, L, Jastrab, J.B, Hu, K, Yu, H, Darwin, K.H, Li, H. | | 登録日 | 2017-01-30 | | 公開日 | 2017-03-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Analysis of Mycobacterium tuberculosis Homologues of the Eukaryotic Proteasome Assembly Chaperone 2 (PAC2).
J. Bacteriol., 199, 2017
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7LJF
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3NLE
 | | Structure of endothelial nitric oxide synthase heme domain complexed with 6-{{(3'R,4'R)-3'-[2"-(3'''-fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6-{[(3R,4R)-4-(2-{[2-(3-fluorophenyl)ethyl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine, ACETATE ION, ... | | 著者 | Ji, H, Delker, S.L, Li, H, Martasek, P, Roman, L, Poulos, T.L, Silverman, R.B. | | 登録日 | 2010-06-21 | | 公開日 | 2010-11-03 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Exploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives.
J.Med.Chem., 53, 2010
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5F4Z
 | | The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus | | 分子名称: | (1~{R},2~{R})-2,3-dihydro-1~{H}-indene-1,2-diol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | | 著者 | Tan, K, Li, H, Jedrzejczak, R, BABNIGG, G, BINGMAN, C.A, YENNAMALLI, R, LOHMAN, J, Chang, C.Y, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2015-12-03 | | 公開日 | 2016-02-17 | | 最終更新日 | 2020-09-23 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus
To Be Published
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3NLD
 | | Structure of endothelial nitric oxide synthase heme domain complexed with 6-{{(3'S,4'S)-3'-[2"-(3'''-fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6-{[(3S,4S)-4-(2-{[2-(3-fluorophenyl)ethyl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine, ACETATE ION, ... | | 著者 | Ji, H, Delker, S.L, Li, H, Martasek, P, Roman, L, Poulos, T.L, Silverman, R.B. | | 登録日 | 2010-06-21 | | 公開日 | 2010-11-03 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.285 Å) | | 主引用文献 | Exploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives.
J.Med.Chem., 53, 2010
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3HJW
 | | Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA | | 分子名称: | 5'-R(*GP*AP*GP*CP*GP*(FHU)P*GP*CP*GP*GP*UP*UP*U)-3', 50S ribosomal protein L7Ae, POTASSIUM ION, ... | | 著者 | Liang, B, Zhou, J, Kahen, E, Terns, R.M, Terns, M.P, Li, H. | | 登録日 | 2009-05-22 | | 公開日 | 2009-06-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA
Nat.Struct.Mol.Biol., 16, 2009
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3M91
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3JWY
 | | Structure of endothelial nitric oxide synthase heme domain complexed with N1-{(3'R,4'S)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLIC ACID, ... | | 著者 | Delker, S.L, Li, H, Poulos, T.L. | | 登録日 | 2009-09-18 | | 公開日 | 2010-05-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model.
J.Am.Chem.Soc., 132, 2010
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1MMV
 | | Rat neuronal NOS heme domain with NG-propyl-L-arginine bound | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-OMEGA-PROPYL-L-ARGININE, ... | | 著者 | Bretscher, L.E, Li, H, Poulos, T.L, Griffith, O.W. | | 登録日 | 2002-09-04 | | 公開日 | 2003-09-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural characterization and kinetics of nitric-oxide synthase inhibition by novel N5-(iminoalkyl)- and N5-(iminoalkenyl)-ornithines
J.Biol.Chem., 278, 2003
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1Y1O
 | | X-ray crystal Structure of Penicillin-binding protein-related factor A from Bacillus stearothermophilus | | 分子名称: | NICKEL (II) ION, Penicillin-binding protein-related factor A, SULFATE ION | | 著者 | Osipiuk, J, Li, H, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2004-11-19 | | 公開日 | 2004-12-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | X-ray crystal Structure of Penicillin-binding protein-related factor A from Bacillus stearothermophilus
To be Published
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2B81
 | | Crystal Structure of the Luciferase-like Monooxygenase from Bacillus cereus | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Luciferase-like monooxygenase, ... | | 著者 | Kim, Y, Li, H, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-10-06 | | 公開日 | 2005-11-22 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of the Luciferase-like Monooxygenase from Bacillus cereus
To be Published
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5BU9
 | | Crystal structure of Beta-N-acetylhexosaminidase from Beutenbergia cavernae DSM 12333 | | 分子名称: | Beta-N-acetylhexosaminidase, GLYCEROL | | 著者 | Chang, C, Tan, K, Li, H, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2015-06-03 | | 公開日 | 2015-06-17 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.255 Å) | | 主引用文献 | Crystal structure of Beta-N-acetylhexosaminidase from Beutenbergia cavernae DSM 12333
To Be Published
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1N97
 | | Crystal Structure of CYP175A1 from Thermus thermophillus strain HB27 | | 分子名称: | 1,2-ETHANEDIOL, CYP175A1, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Yano, J.K, Blasco, F, Li, H, Schmid, R.D, Henne, A, Poulos, T.L. | | 登録日 | 2002-11-22 | | 公開日 | 2003-02-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Preliminary Characterization and Crystal Structure of a Thermostable Cytochrome P450 from Thermus thermophilus
J.Biol.Chem., 278, 2003
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3JX3
 | | Structure of rat neuronal nitric oxide synthase D597N/M336V mutant heme domain in complex with N1-{(3'R,4'R)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-{(3R,4R)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-[2-(3-fluorophenyl)ethyl]ethane-1,2-diamine, ... | | 著者 | Delker, S.L, Li, H, Poulos, T.L. | | 登録日 | 2009-09-18 | | 公開日 | 2010-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model.
J.Am.Chem.Soc., 132, 2010
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3JX0
 | | Structure of rat neuronal nitric oxide synthase D597N mutant heme domain in complex with N1-{(3'S,4'S)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, GLYCEROL, ... | | 著者 | Delker, S.L, Li, H, Poulos, T.L. | | 登録日 | 2009-09-18 | | 公開日 | 2010-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model.
J.Am.Chem.Soc., 132, 2010
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2P0N
 | | NMB1532 protein from Neisseria meningitidis, unknown function | | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, GLYCEROL, ... | | 著者 | Osipiuk, J, Li, H, Bargassa, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-02-28 | | 公開日 | 2007-03-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | X-ray crystal structure of NMB1532 protein of unknown function from Neisseria meningitidis.
To be Published
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6AYG
 | | Human Apo-TRPML3 channel at pH 4.8 | | 分子名称: | Mucolipin-3 | | 著者 | Zhou, X, Li, M, Su, D, Jia, Q, Li, H, Li, X, Yang, J. | | 登録日 | 2017-09-08 | | 公開日 | 2017-11-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.65 Å) | | 主引用文献 | Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states.
Nat. Struct. Mol. Biol., 24, 2017
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3BHG
 | | Crystal structure of adenylosuccinate lyase from Legionella pneumophila | | 分子名称: | Adenylosuccinate lyase, GLYCEROL, SULFATE ION | | 著者 | Chang, C, Li, H, Freeman, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-11-28 | | 公開日 | 2007-12-04 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of adenylosuccinate lyase from Legionella pneumophila.
To be Published
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2FHG
 | | Crystal Structure of Mycobacterial Tuberculosis Proteasome | | 分子名称: | 20S proteasome, alpha and beta subunits, proteasome, ... | | 著者 | Hu, G, Lin, G, Wang, M, Dick, L, Xu, R.M, Nathan, C, Li, H. | | 登録日 | 2005-12-23 | | 公開日 | 2006-02-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.23 Å) | | 主引用文献 | Structure of the Mycobacterium tuberculosis proteasome and mechanism of inhibition by a peptidyl boronate.
Mol.Microbiol., 59, 2006
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2FCK
 | | Structure of a putative ribosomal-protein-serine acetyltransferase from Vibrio cholerae. | | 分子名称: | GLYCEROL, NITRATE ION, ribosomal-protein-serine acetyltransferase, ... | | 著者 | Cuff, M.E, Li, H, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-12-12 | | 公開日 | 2006-02-28 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of an acetyltransferase protein from Vibrio cholerae strain N16961.
Proteins, 69, 2007
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