3NLD
Structure of endothelial nitric oxide synthase heme domain complexed with 6-{{(3'S,4'S)-3'-[2"-(3'''-fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
Summary for 3NLD
Entry DOI | 10.2210/pdb3nld/pdb |
Related | 3NLE 3NLF 3NLG 3NLH 3NLI 3NLJ 3NLK 3NLM 3NLN 3NLO 3NLP 3NLQ 3NLR 3NLT 3NLU 3NLV 3NLW 3NLX 3NLY 3NLZ 3NM0 |
Descriptor | Nitric oxide synthase, endothelial, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (9 entities in total) |
Functional Keywords | nitric oxide synthase, heme enzyme, substrate inhibitor, oxidoreductase |
Biological source | Bos taurus (bovine,cow,domestic cattle,domestic cow) |
Total number of polymer chains | 2 |
Total formula weight | 102524.32 |
Authors | Ji, H.,Delker, S.L.,Li, H.,Martasek, P.,Roman, L.,Poulos, T.L.,Silverman, R.B. (deposition date: 2010-06-21, release date: 2010-11-03, Last modification date: 2024-02-21) |
Primary citation | Ji, H.,Delker, S.L.,Li, H.,Martasek, P.,Roman, L.J.,Poulos, T.L.,Silverman, R.B. Exploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives. J.Med.Chem., 53:7804-7824, 2010 Cited by PubMed: 20958055DOI: 10.1021/jm100947x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.285 Å) |
Structure validation
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