1UTH
 
 | | DntR from Burkholderia sp. strain DNT in complex with Thiocyanate | | Descriptor: | LYSR-TYPE REGULATORY PROTEIN, THIOCYANATE ION | | Authors: | Smirnova, I.A, Dian, C, Leonard, G.A, McSweeney, S, Birse, D, Brzezinski, P. | | Deposit date: | 2003-12-09 | | Release date: | 2004-07-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Development of a Bacterial Biosensor for Nitrotoluenes: The Crystal Structure of the Transcriptional Regulator Dntr
J.Mol.Biol., 340, 2004
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4NB6
 | | Crystal structure of the ligand binding domain of RORC with T0901317 | | Descriptor: | N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, Nuclear receptor ROR-gamma | | Authors: | Hymowitz, S.G, Boenig-de Leon, G. | | Deposit date: | 2013-10-22 | | Release date: | 2013-11-27 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structure-based design of substituted hexafluoroisopropanol-arylsulfonamides as modulators of RORc.
Bioorg.Med.Chem.Lett., 23, 2013
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1UTB
 | | DntR from Burkholderia sp. strain DNT | | Descriptor: | ACETATE ION, GLYCEROL, LYSR-TYPE REGULATORY PROTEIN | | Authors: | Smirnova, I.A, Dian, C, Leonard, G.A, McSweeney, S, Birse, D, Brzezinski, P. | | Deposit date: | 2003-12-05 | | Release date: | 2004-07-01 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Development of a Bacterial Biosensor for Nitrotoluenes: The Crystal Structure of the Transcriptional Regulator Dntr
J.Mol.Biol., 340, 2004
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111D
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404D
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1USP
 | | Organic Hydroperoxide Resistance Protein from Deinococcus radiodurans | | Descriptor: | GLYCEROL, ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN | | Authors: | Meunier-Jamin, C, Kapp, U, Leonard, G, McSweeney, S. | | Deposit date: | 2003-11-27 | | Release date: | 2004-04-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The Structure of the Organic Hydroperoxide Resistance Protein from Deinococcus Radiodurans: Do Conformational Changes Facilitate Recycling of the Redox Disulfide?
J.Biol.Chem., 279, 2004
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2I22
 | | Crystal structure of Escherichia coli phosphoheptose isomerase in complex with reaction substrate sedoheptulose 7-phosphate | | Descriptor: | D-ALTRO-HEPT-2-ULOSE 7-PHOSPHATE, Phosphoheptose isomerase | | Authors: | Blakely, K, Zhang, K, DeLeon, G, Wright, G, Junop, M. | | Deposit date: | 2006-08-15 | | Release date: | 2007-08-21 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure and Function of Sedoheptulose-7-phosphate Isomerase, a Critical Enzyme for Lipopolysaccharide Biosynthesis and a Target for Antibiotic Adjuvants
J.Biol.Chem., 283, 2008
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2PMI
 | | Structure of the Pho85-Pho80 CDK-cyclin Complex of the Phosphate-responsive Signal Transduction Pathway with Bound ATP-gamma-S | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cyclin-dependent protein kinase PHO85, PHO85 cyclin PHO80, ... | | Authors: | Huang, K, Ferrin-O'Connell, I, Zhang, W, Leonard, G.A, O'Shea, E.K, Quiocho, F.A. | | Deposit date: | 2007-04-23 | | Release date: | 2007-12-11 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure of the Pho85-Pho80 CDK-Cyclin Complex of the Phosphate-Responsive Signal Transduction Pathway
Mol.Cell, 28, 2007
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2G3N
 | | Crystal structure of the Sulfolobus solfataricus alpha-glucosidase MalA in complex with beta-octyl-glucopyranoside | | Descriptor: | Alpha-glucosidase, octyl beta-D-glucopyranoside | | Authors: | Ernst, H.A, Lo Leggio, L, Willemoes, M, Leonard, G, Blum, P, Larsen, S. | | Deposit date: | 2006-02-20 | | Release date: | 2006-05-02 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structure of the Sulfolobus solfataricus alpha-Glucosidase: Implications for Domain Conservation and Substrate Recognition in GH31.
J.Mol.Biol., 358, 2006
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2G3M
 | | Crystal structure of the Sulfolobus solfataricus alpha-glucosidase MalA | | Descriptor: | Alpha-glucosidase | | Authors: | Ernst, H.A, Lo Leggio, L, Willemoes, M, Leonard, G, Blum, P, Larsen, S. | | Deposit date: | 2006-02-20 | | Release date: | 2006-05-02 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structure of the Sulfolobus solfataricus alpha-Glucosidase: Implications for Domain Conservation and Substrate Recognition in GH31.
J.Mol.Biol., 358, 2006
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133D
 | | THE CRYSTAL STRUCTURE OF N4-METHYLCYTOSINE.GUANOSIN BASE-PAIRS IN THE SYNTHETIC HEXANUCLEOTIDE D(CGCGM(4)CG) | | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*(C34)P*G)-3') | | Authors: | Cervi, A.R, Guy, A, Leonard, G.A, Teoule, R, Hunter, W.N. | | Deposit date: | 1993-07-29 | | Release date: | 1994-01-15 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The crystal structure of N4-methylcytosine.guanosine base-pairs in the synthetic hexanucleotide d(CGCGm4CG).
Nucleic Acids Res., 21, 1993
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178D
 | | CRYSTAL STRUCTURE OF A DNA DUPLEX CONTAINING 8-HYDROXYDEOXYGUANINE.ADENINE BASE-PAIRS | | Descriptor: | DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*(8OG)P*GP*CP*G)-3') | | Authors: | McAuley-Hecht, K.E, Leonard, G.A, Gibson, N.J, Thomson, J.B, Watson, W.P, Hunter, W.N, Brown, T. | | Deposit date: | 1994-05-19 | | Release date: | 1994-10-04 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of a DNA duplex containing 8-hydroxydeoxyguanine-adenine base pairs.
Biochemistry, 33, 1994
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2VF8
 | | Crystal structure of UvrA2 from Deinococcus radiodurans | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, EXCINUCLEASE ABC SUBUNIT A, PHOSPHATE ION, ... | | Authors: | Timmins, J, Gordon, E, Caria, S, Leonard, G, Kuo, M.S, Monchois, V, McSweeney, S. | | Deposit date: | 2007-10-31 | | Release date: | 2008-12-16 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural and Mutational Analyses of Deinococcus Radiodurans Uvra2 Provide Insight Into DNA Binding and Damage Recognition by Uvras.
Structure, 17, 2009
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2VF7
 | | Crystal structure of UvrA2 from Deinococcus radiodurans | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, EXCINUCLEASE ABC, SUBUNIT A., ... | | Authors: | Timmins, J, Gordon, E, Caria, S, Leonard, G, Kuo, M.S, Monchois, V, McSweeney, S. | | Deposit date: | 2007-10-31 | | Release date: | 2008-12-16 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and mutational analyses of Deinococcus radiodurans UvrA2 provide insight into DNA binding and damage recognition by UvrAs.
Structure, 17, 2009
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1FSE
 | | CRYSTAL STRUCTURE OF THE BACILLUS SUBTILIS REGULATORY PROTEIN GERE | | Descriptor: | GERE, GLYCEROL, SULFATE ION | | Authors: | Ducros, V.M.-A, Lewis, R.J, Verma, C.S, Dodson, E.J, Leonard, G, Turkenburg, J.P, Murshudov, G.N, Wilkinson, A.J, Brannigan, J.A. | | Deposit date: | 2000-09-08 | | Release date: | 2001-03-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Crystal structure of GerE, the ultimate transcriptional regulator of spore formation in Bacillus subtilis.
J.Mol.Biol., 306, 2001
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1W3P
 | | NimA from D. radiodurans with a His71-Pyruvate residue | | Descriptor: | ACETATE ION, NIMA-RELATED PROTEIN, PYRUVIC ACID | | Authors: | Leiros, H.-K.S, Kozielski-Stuhrmann, S, Kapp, U, Terradot, L, Leonard, G.A, McSweeney, S.M. | | Deposit date: | 2004-07-17 | | Release date: | 2004-10-18 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Basis of 5-Nitroimidazole Antibiotic Resistance: The Crystal Structure of Nima from Deinococcus Radiodurans
J.Biol.Chem., 279, 2004
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1W3R
 | | NimA from D. radiodurans with Metronidazole and Pyruvate | | Descriptor: | ACETATE ION, Metronidazole, NIMA-RELATED PROTEIN, ... | | Authors: | Leiros, H.-K.S, Kozielski-Stuhrmann, S, Kapp, U, Terradot, L, Leonard, G.A, McSweeney, S.M. | | Deposit date: | 2004-07-17 | | Release date: | 2004-10-18 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis of 5-Nitroimidazole Antibiotic Resistance: The Crystal Structure of Nima from Deinococcus Radiodurans
J.Biol.Chem., 279, 2004
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1W3Q
 | | NimA from D. radiodurans with covalenly bound lactate | | Descriptor: | ACETATE ION, LACTIC ACID, NIMA-RELATED PROTEIN | | Authors: | Leiros, H.-K.S, Kozielski-Stuhrmann, S, Kapp, U, Terradot, L, Leonard, G.A, Mcsweeney, S.M. | | Deposit date: | 2004-07-17 | | Release date: | 2004-10-18 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Structural Basis of 5-Nitroimidazole Antibiotic Resistance: The Crystal Structure of Nima from Deinococcus Radiodurans
J.Biol.Chem., 279, 2004
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1W3O
 | | Crystal structure of NimA from D. radiodurans | | Descriptor: | ACETATE ION, NIMA-RELATED PROTEIN, PYRUVIC ACID | | Authors: | Leiros, H.-K.S, Kozielski-Stuhrmann, S, Kapp, U, Terradot, L, Leonard, G.A, McSweeney, S.M. | | Deposit date: | 2004-07-17 | | Release date: | 2004-10-18 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural Basis of 5-Nitroimidazole Antibiotic Resistance: The Crystal Structure of Nima from Deinococcus Radiodurans
J.Biol.Chem., 279, 2004
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1DZ3
 | | DOMAIN-SWAPPING IN THE SPORULATION RESPONSE REGULATOR SPO0A | | Descriptor: | SULFATE ION, Stage 0 sporulation protein A | | Authors: | Lewis, R.J, Brannigan, J.A, Muchova, K, Leonard, G, Barak, I, Wilkinson, A.J. | | Deposit date: | 2000-02-15 | | Release date: | 2000-04-10 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Domain swapping in the sporulation response regulator Spo0A.
J. Mol. Biol., 297, 2000
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2GMW
 | | Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli. | | Descriptor: | D,D-heptose 1,7-bisphosphate phosphatase, ZINC ION | | Authors: | Zhang, K, DeLeon, G, Wright, G.D, Junop, M.S. | | Deposit date: | 2006-04-07 | | Release date: | 2007-04-10 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural and kinetic characterization of the LPS biosynthetic enzyme D-alpha,beta-D-heptose-1,7-bisphosphate phosphatase (GmhB) from Escherichia coli.
Biochemistry, 49, 2010
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2UYE
 | | Double mutant Y110S,F111V DntR from Burkholderia sp. strain DNT in complex with thiocyanate | | Descriptor: | GLYCEROL, REGULATORY PROTEIN, THIOCYANATE ION | | Authors: | Lonneborg, R, Smirova, I, Dian, C, leonard, G.A, McSweeney, S, Brzezinski, P. | | Deposit date: | 2007-04-04 | | Release date: | 2007-08-21 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | In Vivo and in Vitro Investigation of Transcriptional Regulation by Dntr.
J.Mol.Biol., 372, 2007
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2UYF
 | | Single mutant F111L DntR from Burkholderia sp. strain DNT in complex with thiocyanate | | Descriptor: | ACETATE ION, GLYCEROL, REGULATORY PROTEIN, ... | | Authors: | Lonneborg, R, Smirova, I, Dian, C, Leonard, G.A, Mcsweeney, S, Brzezinski, P. | | Deposit date: | 2007-04-04 | | Release date: | 2007-08-21 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | In Vivo and in Vitro Investigation of Transcriptional Regulation by Dntr.
J.Mol.Biol., 372, 2007
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242D
 | | MAD PHASING STRATEGIES EXPLORED WITH A BROMINATED OLIGONUCLEOTIDE CRYSTAL AT 1.65 A RESOLUTION. | | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*(CBR)P*G)-3') | | Authors: | Peterson, M.R, Harrop, S.J, McSweeney, S.M, Leonard, G.A, Thompson, A.W, Hunter, W.N, Helliwell, J.R. | | Deposit date: | 1996-06-20 | | Release date: | 1996-09-19 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | MAD Phasing Strategies Explored with a Brominated Oligonucleotide Crystal at 1.65A Resolution.
J.Synchrotron Radiat., 3, 1996
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2Y84
 | | DntR Inducer Binding Domain | | Descriptor: | GLYCEROL, LYSR-TYPE REGULATORY PROTEIN | | Authors: | Devesse, L, Smirnova, I, Lonneborg, R, Kapp, U, Brzezinski, P, Leonard, G.A, Dian, C. | | Deposit date: | 2011-02-03 | | Release date: | 2011-07-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structures of Dntr Inducer Binding Domains in Complex with Salicylate Offer Insights Into the Activation of Lysr-Type Transcriptional Regulators.
Mol.Microbiol., 81, 2011
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