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PDB: 35 results
4HJO
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BU of 4hjo by Molmil
Crystal structure of the inactive EGFR tyrosine kinase domain with erlotinib
Descriptor: Epidermal growth factor receptor, [6,7-BIS(2-METHOXY-ETHOXY)QUINAZOLINE-4-YL]-(3-ETHYNYLPHENYL)AMINE
Authors:Park, J.H, Lemmon, M.A.
Deposit date:2012-10-13
Release date:2012-11-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Erlotinib binds both inactive and active conformations of the EGFR tyrosine kinase domain.
Biochem.J., 448, 2012
3OSM
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BU of 3osm by Molmil
Structure of the Kinase Associated Domain-1 (KA1) from Kcc4p
Descriptor: GLYCEROL, S,R MESO-TARTARIC ACID, serine/threonine-protein kinase KCC4
Authors:Moravcevic, K, Lemmon, M.A.
Deposit date:2010-09-09
Release date:2010-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Kinase Associated-1 Domains Drive MARK/PAR1 Kinases to Membrane Targets by Binding Acidic Phospholipids.
Cell(Cambridge,Mass.), 143, 2010
3OST
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BU of 3ost by Molmil
Structure of the Kinase Associated-1 (KA1) from Kcc4p
Descriptor: GLYCEROL, SULFATE ION, serine/threonine-protein kinase KCC4
Authors:Moravcevic, K, Lemmon, M.A.
Deposit date:2010-09-09
Release date:2010-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.694 Å)
Cite:Kinase Associated-1 Domains Drive MARK/PAR1 Kinases to Membrane Targets by Binding Acidic Phospholipids.
Cell(Cambridge,Mass.), 143, 2010
3OSE
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BU of 3ose by Molmil
Structure of the Kinase Associated Domain 1 (KA1) from MARK1 kinase
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Serine/threonine-protein kinase MARK1
Authors:Moravcevic, K, Lemmon, M.A.
Deposit date:2010-09-08
Release date:2010-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Kinase Associated-1 Domains Drive MARK/PAR1 Kinases to Membrane Targets by Binding Acidic Phospholipids.
Cell(Cambridge,Mass.), 143, 2010
5UTK
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BU of 5utk by Molmil
Crystal structure of the membrane proximal three fibronectin type III (FNIII) domains of Tie2 (Tie2[FNIIIa-c])
Descriptor: Angiopoietin-1 receptor
Authors:Moore, J.O, Lemmon, M.A, Ferguson, K.M.
Deposit date:2017-02-15
Release date:2017-04-12
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dimerization of Tie2 mediated by its membrane-proximal FNIII domains.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1DYN
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BU of 1dyn by Molmil
CRYSTAL STRUCTURE AT 2.2 ANGSTROMS RESOLUTION OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM HUMAN DYNAMIN
Descriptor: DYNAMIN
Authors:Ferguson, K.M, Lemmon, M.A, Schlessinger, J, Sigler, P.B.
Deposit date:1994-12-21
Release date:1995-02-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure at 2.2 A resolution of the pleckstrin homology domain from human dynamin.
Cell(Cambridge,Mass.), 79, 1994
1FHX
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BU of 1fhx by Molmil
Structure of the pleckstrin homology domain from GRP1 in complex with inositol 1,3,4,5-tetrakisphosphate
Descriptor: GUANINE NUCLEOTIDE EXCHANGE FACTOR AND INTEGRIN BINDING PROTEIN HOMOLOG GRP1, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, SULFATE ION
Authors:Ferguson, K.M, Kavran, J.M, Sankaran, V.G, Fournier, E, Isakoff, S.J, Skolnik, E.Y, Lemmon, M.A.
Deposit date:2000-08-02
Release date:2000-08-23
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
Mol.Cell, 6, 2000
1FB8
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BU of 1fb8 by Molmil
STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM DAPP1/PHISH
Descriptor: DUAL ADAPTOR OF PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDES, PHOSPHATE ION
Authors:Ferguson, K.M, Kavran, J.M, Sankaran, V.G, Fournier, E, Isakoff, S.J, Skolnik, E.Y, Lemmon, M.A.
Deposit date:2000-07-14
Release date:2000-07-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains.
Mol.Cell, 6, 2000
1FHW
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BU of 1fhw by Molmil
Structure of the pleckstrin homology domain from GRP1 in complex with inositol(1,3,4,5,6)pentakisphosphate
Descriptor: GUANINE NUCLEOTIDE EXCHANGE FACTOR AND INTEGRIN BINDING PROTEIN HOMOLOG GRP1, INOSITOL-(1,3,4,5,6)-PENTAKISPHOSPHATE, SULFATE ION
Authors:Ferguson, K.M, Kavran, J.M, Sankaran, V.G, Fournier, E, Isakoff, S.J, Skolnik, E.Y, Lemmon, M.A.
Deposit date:2000-08-02
Release date:2000-08-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
Mol.Cell, 6, 2000
1FAO
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BU of 1fao by Molmil
STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM DAPP1/PHISH IN COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE
Descriptor: DUAL ADAPTOR OF PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDES, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE
Authors:Ferguson, K.M, Kavran, J.M, Sankaran, V.G, Fournier, E, Isakoff, S.J, Skolnik, E.Y, Lemmon, M.A.
Deposit date:2000-07-13
Release date:2000-07-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains.
Mol.Cell, 6, 2000
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