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PDB: 349 件
4ZMI
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BU of 4zmi by Molmil
Crystal structure of the Helical domain of S. pombe Taz1
分子名称: COBALT (II) ION, MAGNESIUM ION, Telomere length regulator taz1
著者Deng, W, Wu, J, Wang, F, Lei, M.
登録日2015-05-04
公開日2015-09-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Fission yeast telomere-binding protein Taz1 is a functional but not a structural counterpart of human TRF1 and TRF2.
Cell Res., 25, 2015
4ZOU
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BU of 4zou by Molmil
Crystal structure of the BTB domain of SLX4
分子名称: Structure-specific endonuclease subunit SLX4
著者Wan, B, Chen, Y, Wu, J, Liu, Y, Lei, M.
登録日2015-05-07
公開日2016-05-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The BTB domain is both a structural and functional pivot of the SLX4-nuclease complex
to be published
4ZMK
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BU of 4zmk by Molmil
Crystal structure of the dimerization domain of S. pombe Taz1
分子名称: Telomere length regulator taz1
著者Deng, W, Wu, J, Wang, F, Lei, M.
登録日2015-05-04
公開日2015-09-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Fission yeast telomere-binding protein Taz1 is a functional but not a structural counterpart of human TRF1 and TRF2.
Cell Res., 25, 2015
4M7C
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BU of 4m7c by Molmil
Crystal structure of the TRF2-binding motif of SLX4 in complex with the TRFH domain of TRF2
分子名称: Peptide from Structure-specific endonuclease subunit SLX4, Telomeric repeat-binding factor 2
著者Wan, B, Chen, Y, Wu, J, Liu, Y, Lei, M.
登録日2013-08-12
公開日2013-09-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres
Cell Rep, 4, 2013
5DOI
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BU of 5doi by Molmil
Crystal structure of Tetrahymena p45N and p19
分子名称: Telomerase associated protein p45, Telomerase-associated protein 19
著者Wan, B, Tang, T, Wu, J, Lei, M.
登録日2015-09-11
公開日2015-11-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex
Nat.Struct.Mol.Biol., 22, 2015
2SRC
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BU of 2src by Molmil
CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC, IN COMPLEX WITH AMP-PNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, TYROSINE-PROTEIN KINASE SRC
著者Xu, W, Doshi, A, Lei, M, Eck, M.J, Harrison, S.C.
登録日1998-12-29
公開日1999-07-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structures of c-Src reveal features of its autoinhibitory mechanism.
Mol.Cell, 3, 1999
5DOF
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BU of 5dof by Molmil
Crystal structure of Tetrahymena p19
分子名称: Telomerase-associated protein 19
著者Wan, B, Tang, T, Wu, J, Lei, M.
登録日2015-09-11
公開日2015-11-25
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex.
Nat.Struct.Mol.Biol., 22, 2015
5DOK
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BU of 5dok by Molmil
Crystal structure of Tetrahymena p45C
分子名称: MAGNESIUM ION, Telomerase associated protein p45
著者Wan, B, Tang, T, Wu, J, Lei, M.
登録日2015-09-11
公開日2015-11-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex
Nat.Struct.Mol.Biol., 22, 2015
5F59
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BU of 5f59 by Molmil
The crystal structure of MLL3 SET domain
分子名称: Histone-lysine N-methyltransferase 2C, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
著者Li, Y, Lei, M, Chen, Y.
登録日2015-12-04
公開日2016-02-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F6L
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The crystal structure of MLL1 (N3861I/Q3867L) in complex with RbBP5 and Ash2L
分子名称: Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Li, Y, Lei, M, Chen, Y.
登録日2015-12-06
公開日2016-02-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F5E
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The Crystal Structure of MLL1 SET domain with N3816I/Q3867L mutation
分子名称: Histone-lysine N-methyltransferase 2A, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
著者Li, Y, Lei, M, Chen, Y.
登録日2015-12-04
公開日2016-02-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F6K
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Crystal structure of the MLL3-Ash2L-RbBP5 complex
分子名称: Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Li, Y, Lei, M, Chen, Y.
登録日2015-12-06
公開日2016-02-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.411 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
4O26
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BU of 4o26 by Molmil
Crystal structure of the TRBD domain of TERT and the CR4/5 of TR
分子名称: SULFATE ION, Telomerase TR, Telomerase reverse transcriptase
著者Huang, J, Wu, J, Lei, M.
登録日2013-12-16
公開日2014-05-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献Structural basis for protein-RNA recognition in telomerase.
Nat.Struct.Mol.Biol., 21, 2014
3OIP
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BU of 3oip by Molmil
Crystal structure of Yeast telomere protein Cdc13 OB1
分子名称: Cell division control protein 13
著者Sun, J, Yang, Y, Wan, K, Mao, N, Yu, T.Y, Lin, Y.C, DeZwaan, D.C, Freeman, B.C, Lin, J.J, Lue, N.F, Lei, M.
登録日2010-08-19
公開日2010-11-03
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.504 Å)
主引用文献Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase alpha.
Cell Res., 21, 2011
3RSN
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BU of 3rsn by Molmil
Crystal Structure of the N-terminal region of Human Ash2L
分子名称: Set1/Ash2 histone methyltransferase complex subunit ASH2, ZINC ION
著者Chen, Y, Wan, B, Wang, K.C, Cao, F, Yang, Y, Protacio, A, Dou, Y, Chang, H.Y, Lei, M.
登録日2011-05-02
公開日2011-06-22
最終更新日2011-12-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding.
Embo Rep., 12, 2011
3RMH
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BU of 3rmh by Molmil
Crystal Structure of yeast telomere protein Cdc13 OB4
分子名称: Yeast Cdc13 OB4
著者Sun, J, Yang, Y, Lei, M.
登録日2011-04-20
公開日2011-11-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Analyses of Candida Cdc13 Orthologues Revealed a Novel OB Fold Dimer Arrangement, Dimerization-Assisted DNA Binding, and Substantial Structural Differences between Cdc13 and RPA70.
Mol.Cell.Biol., 32, 2012
3OIQ
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BU of 3oiq by Molmil
Crystal structure of yeast telomere protein Cdc13 OB1 and the catalytic subunit of DNA polymerase alpha Pol1
分子名称: Cell division control protein 13, DNA polymerase alpha catalytic subunit A
著者Sun, J, Yang, Y, Wan, K, Mao, N, Yu, T.Y, Lin, Y.C, DeZwaan, D.C, Freeman, B.C, Lin, J.J, Lue, N.F, Lei, M.
登録日2010-08-19
公開日2010-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase alpha.
Cell Res., 21, 2011
3OWT
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BU of 3owt by Molmil
Crystal structure of S. cerevisiae RAP1-Sir3 complex
分子名称: DNA-binding protein RAP1, Regulatory protein SIR3
著者Chen, Y, Yang, Y, Lei, M.
登録日2010-09-20
公開日2011-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms.
Nat.Struct.Mol.Biol., 18, 2011
6AHV
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BU of 6ahv by Molmil
Crystal structure of human RPP40
分子名称: Ribonuclease P protein subunit p40
著者Wu, J, Niu, S, Tan, M, Lan, P, Lei, M.
登録日2018-08-20
公開日2018-12-05
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Cryo-EM Structure of the Human Ribonuclease P Holoenzyme.
Cell, 175, 2018
6AHU
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BU of 6ahu by Molmil
Cryo-EM structure of human Ribonuclease P with mature tRNA
分子名称: H1 RNA, Ribonuclease P protein subunit p14, Ribonuclease P protein subunit p20, ...
著者Wu, J, Niu, S, Tan, M, Lan, P, Lei, M.
登録日2018-08-20
公開日2018-12-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Cryo-EM Structure of the Human Ribonuclease P Holoenzyme.
Cell, 175, 2018
6AHR
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BU of 6ahr by Molmil
Cryo-EM structure of human Ribonuclease P
分子名称: H1 RNA, Ribonuclease P protein subunit p14, Ribonuclease P protein subunit p20, ...
著者Wu, J, Niu, S, Tan, M, Lan, P, Lei, M.
登録日2018-08-20
公開日2018-12-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Cryo-EM Structure of the Human Ribonuclease P Holoenzyme.
Cell, 175, 2018
3U50
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BU of 3u50 by Molmil
Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 OB-C
分子名称: Telomerase-associated protein 82, ZINC ION
著者Zeng, Z, Huang, J, Yang, Y, Lei, M.
登録日2011-10-10
公開日2011-12-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U84
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Crystal Structure of Human Menin
分子名称: Menin
著者Huang, J, Wan, B, Lei, M.
登録日2011-10-15
公開日2012-02-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
8HMD
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base module state 2 of Tetrahymena IFT-A
分子名称: Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, Tetratricopeptide repeat protein, ...
著者Ma, Y, Wu, J, Lei, M.
登録日2022-12-03
公開日2023-06-14
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train.
Nat Commun, 14, 2023
8HME
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head module state 1 of Tetrahymena IFT-A
分子名称: Intraflagellar transport protein 122 homolog, Intraflagellar transporter, WD40 repeat protein, ...
著者Ma, Y, Wu, J, Lei, M.
登録日2022-12-03
公開日2023-06-14
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train.
Nat Commun, 14, 2023

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