5F4E
 
 | | Crystal structure of the human sperm Izumo1 and egg Juno complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | | Authors: | Aydin, H, Sultana, A, Lee, J.E. | | Deposit date: | 2015-12-03 | | Release date: | 2016-06-15 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex.
Nature, 534, 2016
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5F4V
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5F4T
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2M55
 | | NMR structure of the complex of an N-terminally acetylated alpha-synuclein peptide with calmodulin | | Descriptor: | Alpha-synuclein, CALCIUM ION, Calmodulin | | Authors: | Gruschus, J.M, Yap, T, Pistolesi, S, Maltsev, A.S, Lee, J.C. | | Deposit date: | 2013-02-13 | | Release date: | 2013-05-08 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | NMR Structure of Calmodulin Complexed to an N-Terminally Acetylated alpha-Synuclein Peptide.
Biochemistry, 52, 2013
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3BL6
 | | Crystal structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase in complex with formycin A | | Descriptor: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase | | Authors: | Siu, K.K.W, Lee, J.E, Smith, G.D, Horvatin, C, Howell, P.L. | | Deposit date: | 2007-12-10 | | Release date: | 2008-06-10 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Acta Crystallogr.,Sect.F, 64, 2008
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3E3Z
 | | Crystal structure of bovine coupling Factor B bound with phenylarsine oxide | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP synthase subunit s, mitochondrial, ... | | Authors: | Stroud, R.M, Lee, J.K, Belogrudov, G.I. | | Deposit date: | 2008-08-08 | | Release date: | 2008-08-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of bovine mitochondrial factor B at 0.96-A resolution.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3E4G
 | | Crystal structure of bovine coupling Factor B, G28E mutant | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP synthase subunit s, mitochondrial, ... | | Authors: | Stroud, R.M, Lee, J.K, Belogrudov, G.I. | | Deposit date: | 2008-08-11 | | Release date: | 2008-08-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (0.96 Å) | | Cite: | Crystal structure of bovine mitochondrial factor B at 0.96-A resolution.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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5H38
 | | Structural analysis of KSHV thymidylate synthase | | Descriptor: | ORF70, PHOSPHATE ION | | Authors: | Choi, Y.M, Yeo, H.K, Park, Y.W, Lee, J.Y. | | Deposit date: | 2016-10-21 | | Release date: | 2017-01-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural Analysis of Thymidylate Synthase from Kaposi's Sarcoma-Associated Herpesvirus with the Anticancer Drug Raltitrexed.
PLoS ONE, 11, 2016
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5H3A
 | | Structural analysis of KSHV thymidylate synthase | | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ORF70, TOMUDEX | | Authors: | Choi, Y.M, Yeo, H.K, Park, Y.W, Lee, J.Y. | | Deposit date: | 2016-10-21 | | Release date: | 2017-01-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Analysis of Thymidylate Synthase from Kaposi's Sarcoma-Associated Herpesvirus with the Anticancer Drug Raltitrexed.
PLoS ONE, 11, 2016
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5H39
 | | Structural analysis of KSHV thymidylate synthase | | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ORF70 | | Authors: | Choi, Y.M, Yeo, H.K, Park, Y.W, Lee, J.Y. | | Deposit date: | 2016-10-21 | | Release date: | 2017-01-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Analysis of Thymidylate Synthase from Kaposi's Sarcoma-Associated Herpesvirus with the Anticancer Drug Raltitrexed.
PLoS ONE, 11, 2016
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5HA6
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3SNV
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3SI8
 | | Human DNA polymerase eta - DNA ternary complex with the 5'T of a CPD in the active site (TT2) | | Descriptor: | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, ... | | Authors: | Biertumpfel, C, Zhao, Y, Kondo, Y, Ramon-Maiques, S, Gregory, M, Lee, J.Y, Masutani, C, Lehmann, A.R, Hanaoka, F, Yang, W. | | Deposit date: | 2011-06-17 | | Release date: | 2011-08-03 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structure and mechanism of human DNA polymerase eta.
Nature, 465, 2010
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2OLE
 | | Crystal Structure Of Human Dipeptidyl Peptidase IV (DPPIV) Complex With Cyclic Hydrazine Derivatives | | Descriptor: | (2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE, Dipeptidyl peptidase 4 | | Authors: | Kim, S.S, Ahn, J.H, Lee, J.O. | | Deposit date: | 2007-01-19 | | Release date: | 2008-01-22 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Synthesis, biological evaluation and structural determination of beta-aminoacyl-containing cyclic hydrazine derivatives as dipeptidyl peptidase IV (DPP-IV) inhibitors
Bioorg.Med.Chem.Lett., 17, 2007
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1BI7
 | | MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURE OF THE CDK6-P16INK4A TUMOR SUPPRESSOR COMPLEX | | Descriptor: | CYCLIN-DEPENDENT KINASE 6, MULTIPLE TUMOR SUPPRESSOR | | Authors: | Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P. | | Deposit date: | 1998-06-22 | | Release date: | 1999-01-13 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
Nature, 395, 1998
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4FJS
 | | Crystal structure of ureidoglycolate dehydrogenase enzyme in apo form | | Descriptor: | Ureidoglycolate dehydrogenase | | Authors: | Kim, M.I, Shin, I, Lee, J, Rhee, S. | | Deposit date: | 2012-06-12 | | Release date: | 2013-01-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | Structural and functional insights into (s)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization.
Plos One, 7, 2012
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5W8N
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2HB1
 | | Crystal Structure of PTP1B with Monocyclic Thiophene Inhibitor | | Descriptor: | 4-BROMO-3-(CARBOXYMETHOXY)THIOPHENE-2-CARBOXYLIC ACID, Tyrosine-protein phosphatase non-receptor type 1 | | Authors: | Xu, W, Wan, Z.-K, Lee, J. | | Deposit date: | 2006-06-13 | | Release date: | 2006-08-29 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Monocyclic thiophenes as protein tyrosine phosphatase 1B inhibitors: Capturing interactions with Asp48.
Bioorg.Med.Chem.Lett., 16, 2006
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2IS2
 | | Crystal structure of UvrD-DNA binary complex | | Descriptor: | 33-MER, DNA helicase II, FORMIC ACID, ... | | Authors: | Yang, W, Lee, J.Y. | | Deposit date: | 2006-10-16 | | Release date: | 2007-01-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke.
Cell(Cambridge,Mass.), 127, 2006
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3S2P
 | | Crystal structure of CDK2 with a 2-aminopyrimidine compound | | Descriptor: | (3S,4S)-1-{3-[2-amino-6-(propan-2-yl)pyrimidin-4-yl]-4-hydroxyphenyl}pyrrolidine-3,4-diol, Cyclin-dependent kinase 2 | | Authors: | Kim, K.-H, Lee, J, Jeong, S. | | Deposit date: | 2011-05-17 | | Release date: | 2011-07-20 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Discovery of a novel class of 2-aminopyrimidines as CDK1 and CDK2 inhibitors
Bioorg.Med.Chem.Lett., 21, 2011
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5W8X
 | | Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP | | Descriptor: | Lipid-A-disaccharide synthase, URIDINE-5'-DIPHOSPHATE | | Authors: | Bohl, T.E, Aihara, H, Shi, K, Lee, J.K. | | Deposit date: | 2017-06-22 | | Release date: | 2018-01-31 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Crystal structure of lipid A disaccharide synthase LpxB from Escherichia coli.
Nat Commun, 9, 2018
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5ZLI
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5W8S
 | | Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations | | Descriptor: | LITHIUM ION, Lipid-A-disaccharide synthase, SODIUM ION | | Authors: | Bohl, T.E, Aihara, H, Shi, K, Lee, J.K. | | Deposit date: | 2017-06-22 | | Release date: | 2018-01-31 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of lipid A disaccharide synthase LpxB from Escherichia coli.
Nat Commun, 9, 2018
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4QIS
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4QIT
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