5H3A

Structural analysis of KSHV thymidylate synthase

Summary for 5H3A

• Entry DOI: 10.2210/pdb5h3a/pdb
• Related: 5H38 5H39
• Descriptor: ORF70, TOMUDEX, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ... (4 entities in total)
• Functional Keywords: thymidylate synthase, inhibitor, raltitrexed, dump, transferase
• Biological source: Human herpesvirus 8 (HHV-8)
• Total number of polymer chains: 2
• Total formula weight: 66774.09

Authors

Choi, Y.M.,Yeo, H.K.,Park, Y.W.,Lee, J.Y. (deposition date: 2016-10-21, release date: 2017-01-18, Last modification date: 2023-11-08)

• Primary citation: Choi, Y.M.,Yeo, H.K.,Park, Y.W.,Lee, J.Y.; Structural Analysis of Thymidylate Synthase from Kaposi's Sarcoma-Associated Herpesvirus with the Anticancer Drug Raltitrexed.; PLoS ONE, 11:e0168019-e0168019, 2016; PubMed: 27936107; DOI: 10.1371/journal.pone.0168019

Experimental method

X-RAY DIFFRACTION (2.4 Å)