7L8J
 
 | | SARS-CoV-2 Main Protease (Mpro) in Complex with Rupintrivir (P21212) | | 分子名称: | 3C-like proteinase, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | | 著者 | Lockbaum, G.J, Henes, M, Lee, J.M, Timm, J, Nalivaika, E.A, Yilmaz, N.K, Thompson, P.R, Schiffer, C.A. | | 登録日 | 2020-12-31 | | 公開日 | 2021-09-22 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode.
Biochemistry, 60, 2021
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7L8H
 | | EV68 3C protease (3Cpro) in Complex with Rupintrivir | | 分子名称: | 3C Protease, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | | 著者 | Lockbaum, G.J, Henes, M, Lee, J.M, Timm, J, Nalivaika, E.A, Yilmaz, N.K, Thompson, P.R, Schiffer, C.A. | | 登録日 | 2020-12-31 | | 公開日 | 2021-09-22 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode.
Biochemistry, 60, 2021
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6JZL
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3ROU
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6BVB
 | | Crystal structure of HIF-2alpha-pVHL-elongin B-elongin C | | 分子名称: | Elongin-B, Elongin-C, Hypoxia-Inducible Factor 2 alpha, ... | | 著者 | Tarade, D, Ohh, M, Lee, J.E. | | 登録日 | 2017-12-12 | | 公開日 | 2018-08-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | | 主引用文献 | HIF-2 alpha-pVHL complex reveals broad genotype-phenotype correlations in HIF-2 alpha-driven disease.
Nat Commun, 9, 2018
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2KCC
 | | Solution Structure of biotinoyl domain from human acetyl-CoA carboxylase 2 | | 分子名称: | Acetyl-CoA carboxylase 2 | | 著者 | Lee, C, Cheong, H, Ryu, K, Lee, J, Lee, W, Jeon, Y, Cheong, C. | | 登録日 | 2008-12-19 | | 公開日 | 2009-02-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Biotinoyl domain of human acetyl-CoA carboxylase: Structural insights into the carboxyl transfer mechanism.
Proteins, 72, 2008
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3E2J
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3TJ6
 | | human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-C; residues 812-835) from Rickettsia rickettsii | | 分子名称: | Antigenic heat-stable 120 kDa protein, Vinculin | | 著者 | Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T. | | 登録日 | 2011-08-23 | | 公開日 | 2011-09-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
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3RPQ
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3RYP
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3QOP
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3RYR
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5ZZ6
 | | Redox-sensing transcriptional repressor Rex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Redox-sensing transcriptional repressor Rex 1 | | 著者 | Park, Y.W, Jang, Y.Y, Joo, H.K, Lee, J.Y. | | 登録日 | 2018-05-30 | | 公開日 | 2018-11-07 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Analysis of Redox-sensing Transcriptional Repressor Rex from Thermotoga maritima
Sci Rep, 8, 2018
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4JPR
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3RDI
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7CQ0
 | | Crystal structure of Streptoavidin-C1 from Streptomyces cinamonensis | | 分子名称: | Mature Streptoavidin-C1 | | 著者 | Jeon, B.J, Kim, S, Lee, J.-H, Kim, M.S, Hwang, K.Y. | | 登録日 | 2020-08-08 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Insights into the structure of mature streptavidin C1 from Streptomyces cinnamonensis reveal the self-binding of the extension C-terminal peptide to biotin-binding sites.
Iucrj, 8, 2021
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7CPZ
 | | Crystal structure of Streptoavidin-C1 from Streptomyces cinamonensis | | 分子名称: | BIOTIN, Mature Streptoavidin-C1 | | 著者 | Jeon, B.J, Kim, S, Lee, J.-H, Kim, M.S, Hwang, K.Y. | | 登録日 | 2020-08-08 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Insights into the structure of mature streptavidin C1 from Streptomyces cinnamonensis reveal the self-binding of the extension C-terminal peptide to biotin-binding sites.
Iucrj, 8, 2021
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3CRG
 | | Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ala, Glu82Asn and Lys101Ala | | 分子名称: | FORMIC ACID, GLYCEROL, Heparin-binding growth factor 1, ... | | 著者 | Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M. | | 登録日 | 2008-04-07 | | 公開日 | 2009-02-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
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3MR3
 | | Human DNA polymerase eta - DNA ternary complex with the 3'T of a CPD in the active site (TT1) | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*AP*(TTD)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*CP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... | | 著者 | Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W. | | 登録日 | 2010-04-28 | | 公開日 | 2010-06-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structure and mechanism of human DNA polymerase eta.
Nature, 465, 2010
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3MR5
 | | Human DNA polymerase eta - DNA ternary complex with a CPD 1bp upstream of the active site (TT3) | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*CP*GP*TP*CP*AP*TP*AP*A)-3'), DNA (5'-D(*TP*AP*AP*CP*(TTD)P*AP*TP*GP*AP*CP*GP*A)-3'), ... | | 著者 | Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W. | | 登録日 | 2010-04-28 | | 公開日 | 2010-06-30 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure and mechanism of human DNA polymerase eta.
Nature, 465, 2010
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3E2W
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7UJV
 | | Structure of PHD2 in complex with HIF2a-CODD | | 分子名称: | Egl nine homolog 1, Endothelial PAS domain-containing protein 1, FE (III) ION, ... | | 著者 | Ferens, F.G, Tarade, D, Lee, J.E, Ohh, M. | | 登録日 | 2022-03-31 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Deficiency in PHD2-mediated hydroxylation of HIF2 alpha underlies Pacak-Zhuang syndrome.
Commun Biol, 7, 2024
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2GEF
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3E24
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3MR6
 | | Human DNA polymerase eta - DNA ternary complex with a CPD 2bp upstream of the active site (TT4) | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*C*AP*TP*CP*AP*(TTD)P*AP*CP*GP*AP*GP*C)-3'), DNA (5'-D(*TP*CP*TP*CP*GP*TP*AP*AP*T)-3'), ... | | 著者 | Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W. | | 登録日 | 2010-04-28 | | 公開日 | 2010-06-30 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and mechanism of human DNA polymerase eta.
Nature, 465, 2010
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