7WG3
| Structural basis of interleukin-17B receptor in complex with a neutralizing antibody D9 for guiding humanization and affinity maturation for cancer therapy | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of D9 Fab, IL17RB protein, ... | 著者 | Lee, W.H, Chen, X.R, Liu, I.J, Lee, J.H, Hu, C.M, Wu, H.C, Wang, S.K, Lee, W.H, Ma, C. | 登録日 | 2021-12-28 | 公開日 | 2022-11-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation. Cell Rep, 41, 2022
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5GS2
| Crystal structure of diabody complex with repebody and MBP | 分子名称: | Maltose-binding periplasmic protein, anti-MBP, anti-repebody, ... | 著者 | Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. | 登録日 | 2016-08-13 | 公開日 | 2016-10-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.592 Å) | 主引用文献 | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface. Sci Rep, 6, 2016
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7CM4
| Crystal Structure of COVID-19 virus spike receptor-binding domain complexed with a neutralizing antibody CT-P59 | 分子名称: | 1,2-ETHANEDIOL, IgG heavy chain, IgG light chain, ... | 著者 | Kim, Y.G, Jeong, J.H, Bae, J.S, Lee, J. | 登録日 | 2020-07-24 | 公開日 | 2021-01-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein. Nat Commun, 12, 2021
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1N6A
| Structure of SET7/9 | 分子名称: | S-ADENOSYLMETHIONINE, SET domain-containing protein 7 | 著者 | Kwon, T.W, Chang, J.H, Kwak, E, Lee, C.W, Joachimiak, A, Kim, Y.C, Lee, J, Cho, Y. | 登録日 | 2002-11-09 | 公開日 | 2003-02-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet EMBO J., 22, 2003
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1WOG
| Crystal Structure of Agmatinase Reveals Structural Conservation and Inhibition Mechanism of the Ureohydrolase Superfamily | 分子名称: | HEXANE-1,6-DIAMINE, MANGANESE (II) ION, agmatinase | 著者 | Ahn, H.J, Kim, K.H, Lee, J, Ha, J.-Y, Lee, H.H, Kim, D, Yoon, H.-J, Kwon, A.-R, Suh, S.W. | 登録日 | 2004-08-18 | 公開日 | 2004-09-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily J.Biol.Chem., 279, 2004
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1WOH
| Crystal Structure of Agmatinase Reveals Structural Conservation and Inhibition Mechanism of the Ureohydrolase Superfamily | 分子名称: | agmatinase | 著者 | Ahn, H.J, Kim, K.H, Lee, J, Ha, J.-Y, Lee, H.H, Kim, D, Yoon, H.-J, Kwon, A.-R, Suh, S.W. | 登録日 | 2004-08-18 | 公開日 | 2004-09-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily J.Biol.Chem., 279, 2004
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1IX1
| Crystal Structure of P.aeruginosa Peptide deformylase Complexed with Antibiotic Actinonin | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, ACTINONIN, ZINC ION, ... | 著者 | Kim, H.-W, Yoon, H.-J, Lee, J.Y, Han, B.W, Yang, J.K, Lee, B.I, Ahn, H.J, Lee, H.H, Suh, S.W. | 登録日 | 2002-06-07 | 公開日 | 2003-09-09 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of peptide deformylase from Staphylococcus aureus in complex with actinonin, a naturally occurring antibacterial agent Proteins, 57, 2004
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1WOI
| Crystal Structure of Agmatinase Reveals Structural Conservation and Inhibition Mechanism of the Ureohydrolase Superfamily | 分子名称: | MANGANESE (II) ION, agmatinase | 著者 | Ahn, H.J, Kim, K.H, Lee, J, Ha, J.-Y, Lee, H.H, Kim, D, Yoon, H.-J, Kwon, A.-R, Suh, S.W. | 登録日 | 2004-08-18 | 公開日 | 2004-09-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily J.Biol.Chem., 279, 2004
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1J38
| Crystal Structure of Drosophila AnCE | 分子名称: | ZINC ION, angiotensin converting enzyme | 著者 | Kim, H.M, Shin, D.R, Lee, H, Lee, J.-O. | 登録日 | 2003-01-20 | 公開日 | 2003-07-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of Drosophila angiotensin I-converting enzyme bound to captopril and lisinopril Febs Lett., 538, 2003
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1J9J
| CRYSTAL STRUCTURE ANALYSIS OF SURE PROTEIN FROM T.MARITIMA | 分子名称: | MAGNESIUM ION, STATIONARY PHASE SURVIVAL PROTEIN, SULFATE ION | 著者 | Suh, S.W, Lee, J.Y, Kwak, J.E, Moon, J. | 登録日 | 2001-05-27 | 公開日 | 2001-09-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure and functional analysis of the SurE protein identify a novel phosphatase family. Nat.Struct.Biol., 8, 2001
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5TSP
| Crystal structure of the catalytic domain of Clostridium perfringens neuraminidase (NanI) in complex with a CHES | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, Sialidase | 著者 | Lee, Y, Youn, H.-S, Lee, J.-G, An, J.Y, Park, K.R, Kang, J.Y, Jin, M.S, Ryu, Y.B, Park, K.H, Eom, S.H. | 登録日 | 2016-10-31 | 公開日 | 2017-03-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Crystal structure of the catalytic domain of Clostridium perfringens neuraminidase in complex with a non-carbohydrate-based inhibitor, 2-(cyclohexylamino)ethanesulfonic acid Biochem. Biophys. Res. Commun., 486, 2017
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8CZ7
| Crystal structure of SARS-CoV-2 Mpro with compound C2 | 分子名称: | 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)-N-(4-methoxyphenyl)acetamide | 著者 | Worrall, L.J, Lee, J, Strynadka, N.C.J. | 登録日 | 2022-05-24 | 公開日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
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8CYZ
| Crystal structure of SARS-CoV-2 Mpro with compound C4 | 分子名称: | 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)-N-[4-(methylsulfanyl)phenyl]acetamide | 著者 | Worrall, L.J, Lee, J, Strynadka, N.C.J. | 登録日 | 2022-05-24 | 公開日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
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8CYU
| Crystal structure of SARS-CoV-2 Mpro with compound C5 | 分子名称: | 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-N-[4-(dimethylamino)phenyl]-2-(isoquinolin-4-yl)acetamide | 著者 | Worrall, L.J, Lee, J, Strynadka, N.C.J. | 登録日 | 2022-05-24 | 公開日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
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8CZ4
| Crystal structure of SARS-CoV-2 Mpro with compound C3 | 分子名称: | 3C-like proteinase, N-(4-tert-butylphenyl)-N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)acetamide | 著者 | Worrall, L.J, Lee, J, Strynadka, N.C.J. | 登録日 | 2022-05-24 | 公開日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
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4MM2
| Crystal structure of yeast primase catalytic subunit | 分子名称: | CADMIUM ION, CITRIC ACID, DNA primase small subunit | 著者 | Park, K.R, An, J.Y, Lee, Y, Youn, H.S, Lee, J.G, Kang, J.Y, Kim, T.G, Lim, J.J, Eom, S.H, Wang, J. | 登録日 | 2013-09-07 | 公開日 | 2014-09-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of yeast primase catalytic subunit To be Published
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7VPF
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7NFX
| Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A | 分子名称: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Jomaa, A, Lee, J.H, Shan, S, Ban, N. | 登録日 | 2021-02-08 | 公開日 | 2021-06-02 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER. Sci Adv, 7, 2021
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4XTT
| Structural Studies of Potassium Transport Protein KtrA Regulator of Conductance of K+ (RCK) C domain in Complex with Cyclic Diadenosine Monophosphate (c-di-AMP) | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Putative potassium transport protein | 著者 | Kim, H, Youn, S.J, Kim, S.O, Ko, J, Lee, J.O, Choi, B.S. | 登録日 | 2015-01-24 | 公開日 | 2015-05-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.708 Å) | 主引用文献 | Structural Studies of Potassium Transport Protein KtrA Regulator of Conductance of K+ (RCK) C Domain in Complex with Cyclic Diadenosine Monophosphate (c-di-AMP) J.Biol.Chem., 290, 2015
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6ILB
| Native crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi | 分子名称: | 1,2-ETHANEDIOL, Fructuronate-tagaturonate epimerase UxaE, MANGANESE (II) ION | 著者 | Choi, M.Y, Kang, L.W, Ho, T.H, Nguyen, D.Q, Lee, I.H, Lee, J.H, Park, Y.S, Park, H.J. | 登録日 | 2018-10-17 | 公開日 | 2019-10-23 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi To be published
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5GRU
| Structure of mono-specific diabody | 分子名称: | Maltose-binding periplasmic protein, diabody protein | 著者 | Kim, J.H, Song, D.H, Youn, S.J, Cho, G, Lee, H, Lee, J.O. | 登録日 | 2016-08-12 | 公開日 | 2016-10-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.955 Å) | 主引用文献 | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface. Sci Rep, 6, 2016
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6ILA
| Two Glycerol complexed Crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi | 分子名称: | Fructuronate-tagaturonate epimerase UxaE, GLYCEROL, PHOSPHATE ION, ... | 著者 | Choi, M.Y, Kang, L.W, Ho, T.H, Nguyen, D.Q, Lee, I.H, Lee, J.H, Park, Y.S, Park, H.J. | 登録日 | 2018-10-17 | 公開日 | 2019-10-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi To be published
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5H0P
| Crystal structure of EF-hand protein mutant | 分子名称: | CALCIUM ION, EF-hand domain-containing protein D2 | 著者 | Park, K.R, An, J.Y, Kang, J.Y, Lee, J.G, Youn, H.S, Lee, Y, Mun, S.A, Jun, C.D, Song, W.K, Eom, S.H. | 登録日 | 2016-10-06 | 公開日 | 2017-09-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.862 Å) | 主引用文献 | Structural mechanism underlying regulation of human EFhd2/Swiprosin-1 actin-bundling activity by Ser183 phosphorylation. Biochem. Biophys. Res. Commun., 483, 2017
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6IL9
| One Glycerol complexed Crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi | 分子名称: | Fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi in complex with 1 glycerol, GLYCEROL, ZINC ION | 著者 | Choi, M.Y, Kang, L.W, Ho, T.H, Nguyen, D.Q, Lee, I.H, Lee, J.H, Park, Y.S, Park, H.J. | 登録日 | 2018-10-17 | 公開日 | 2019-10-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.72005355 Å) | 主引用文献 | Crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi To Be Published
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5XMH
| Crystal structure of an IgM rheumatoid factor YES8c in complex with IgG1 Fc | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain, ... | 著者 | Shiroishi, M, Shimokawa, K, Lee, J.M, Kusakabe, M, Ueda, T. | 登録日 | 2017-05-15 | 公開日 | 2018-03-21 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-function analyses of a stereotypic rheumatoid factor unravel the structural basis for germline-encoded antibody autoreactivity. J. Biol. Chem., 293, 2018
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