8SZR
| Dog DHX9 bound to ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RNA helicase, ... | Authors: | Lee, Y.-T, Sickmier, E.A, Grigoriu, S, Boriack-Sjodin, P.A. | Deposit date: | 2023-05-30 | Release date: | 2023-08-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Crystal structures of the DExH-box RNA helicase DHX9. Acta Crystallogr D Struct Biol, 79, 2023
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4EK1
| Crystal Structure of Electron-Spin Labeled Cytochrome P450cam | Descriptor: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | Authors: | Lee, Y.-T, Goodin, D.B. | Deposit date: | 2012-04-08 | Release date: | 2012-07-25 | Last modified: | 2012-08-29 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Double electron-electron resonance shows cytochrome P450cam undergoes a conformational change in solution upon binding substrate. Proc.Natl.Acad.Sci.USA, 109, 2012
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1K0F
| Crystal structure of Zn(II)-free T. pallidum TroA | Descriptor: | Periplasmic zinc-binding protein troA | Authors: | Lee, Y.H, Dorwart, M.R, Hazlett, K.R, Deka, R.K, Norgard, M.V, Radolf, J.D, Hasemann, C.A. | Deposit date: | 2001-09-19 | Release date: | 2002-04-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of Zn(II)-free Treponema pallidum TroA, a periplasmic metal-binding protein, reveals a closed conformation. J.Bacteriol., 184, 2002
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3IKL
| Crystal structure of Pol gB delta-I4. | Descriptor: | DNA polymerase subunit gamma-2, mitochondrial | Authors: | Lee, Y.S, Kennedy, W.D, Yin, Y.W. | Deposit date: | 2009-08-06 | Release date: | 2010-08-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations. Cell(Cambridge,Mass.), 139, 2009
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1K6M
| Crystal Structure of Human Liver 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase | Descriptor: | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2-phosphatase, PHOSPHATE ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Lee, Y.H, Li, Y, Uyeda, K, Hasemann, C.A. | Deposit date: | 2001-10-16 | Release date: | 2002-12-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Tissue-specific structure/function differentiation of the liver isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. J.Biol.Chem., 278, 2003
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7LHQ
| Solution structure of SARS-CoV-2 nonstructural protein 7 at pH 7.0 | Descriptor: | Non-structural protein 7 | Authors: | Lee, Y, Tonelli, M, Anderson, T.K, Kirchdoerfer, R.N, Henzler-Wildman, K, Lee, W. | Deposit date: | 2021-01-26 | Release date: | 2022-02-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | pH-dependent polymorphism of the structure of SARS-CoV-2 nsp7 Biorxiv, 2021
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4HQR
| Crystal Structure of mutant form of Caspase-7 | Descriptor: | Ac-Asp-Glu-Val-Asp-Aldehyde, Caspase-7 | Authors: | Lee, Y, Kang, H.J, Bae, K.-H, Kim, S.J, Chung, S.J. | Deposit date: | 2012-10-26 | Release date: | 2013-09-11 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural asymmetry of procaspase-7 bound to a specific inhibitor Acta Crystallogr.,Sect.D, 69, 2013
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4HQ0
| Crystal Structure of mutant form of Caspase-7 | Descriptor: | Caspase-7 | Authors: | Lee, Y, Kang, H.J, Bae, K.-H, Kim, S.J, Chung, S.J. | Deposit date: | 2012-10-25 | Release date: | 2013-09-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural asymmetry of procaspase-7 bound to a specific inhibitor Acta Crystallogr.,Sect.D, 69, 2013
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5HIJ
| Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with betaine | Descriptor: | Glycine sarcosine N-methyltransferase, TRIMETHYL GLYCINE | Authors: | Lee, Y.R, Lin, T.S, Lai, S.J, Liu, M.S, Lai, M.C, Chan, N.L. | Deposit date: | 2016-01-12 | Release date: | 2016-11-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity Sci Rep, 6, 2016
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5HIM
| Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with S-adenosylhomocysteine and dimethylglycine | Descriptor: | 1,2-ETHANEDIOL, Glycine sarcosine N-methyltransferase, N,N-DIMETHYLGLYCINE, ... | Authors: | Lee, Y.R, Lin, T.S, Lai, S.J, Liu, M.S, Lai, M.C, Chan, N.L. | Deposit date: | 2016-01-12 | Release date: | 2016-11-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.338 Å) | Cite: | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity Sci Rep, 6, 2016
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6JG0
| Crystal structure of the N-terminal domain single mutant (S92E) of the human mitochondrial calcium uniporter fused with T4 lysozyme | Descriptor: | Endolysin,Calcium uniporter protein, SULFATE ION | Authors: | Lee, Y, Park, J, Min, C.K, Kang, J.Y, Kim, T.G, Yamamoto, T, Kim, D.H, Eom, S.H. | Deposit date: | 2019-02-13 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of calcium channel domain To Be Published
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5HII
| Crystal structure of glycine sarcosine N-methyltransferase (GSMT) from Methanohalophilus portucalensis (apo form) | Descriptor: | 1,2-ETHANEDIOL, Glycine sarcosine N-methyltransferase | Authors: | Lee, Y.R, Lin, T.S, Lai, S.J, Liu, M.S, Lai, M.C, Chan, N.L. | Deposit date: | 2016-01-12 | Release date: | 2016-11-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity Sci Rep, 6, 2016
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4MA4
| S-glutathionylated PFKFB3 | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3, ACETIC ACID, ... | Authors: | Lee, Y.-H, Seo, M.-S. | Deposit date: | 2013-08-15 | Release date: | 2013-12-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | PFKFB3 Regulates Oxidative Stress Homeostasis via Its S-Glutathionylation in Cancer. J.Mol.Biol., 426, 2014
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2F7N
| Structure of D. radiodurans Dps-1 | Descriptor: | COBALT (II) ION, DNA-binding stress response protein, Dps family, ... | Authors: | Lee, Y.H, Kim, S.G, Bhattacharyya, G, Grove, A. | Deposit date: | 2005-12-01 | Release date: | 2006-11-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of Dps-1, a functionally distinct Dps protein from Deinococcus radiodurans. J.Mol.Biol., 361, 2006
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3L62
| Crystal structure of substrate-free P450cam at low [K+] | Descriptor: | Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Lee, Y.-T, Wilson, R.F, Rupniewski, I, Goodin, D.B. | Deposit date: | 2009-12-22 | Release date: | 2010-04-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | P450cam visits an open conformation in the absence of substrate. Biochemistry, 49, 2010
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4QFQ
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6JMQ
| LAT1-CD98hc complex bound to MEM-108 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, ... | Authors: | Lee, Y, Nishizawa, T, Kusakizako, T, Oda, K, Ishitani, R, Nakane, T, Nureki, O. | Deposit date: | 2019-03-13 | Release date: | 2019-06-19 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.31 Å) | Cite: | Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc. Nat.Struct.Mol.Biol., 26, 2019
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5EUR
| Hypothetical protein SF216 from shigella flexneri 5a M90T | Descriptor: | MAGNESIUM ION, SULFATE ION, Uncharacterized protein | Authors: | Lee, Y.-S, Seok, S.-H, Kim, H.-N, An, J.-G, Chung, K.Y, Won, H.-S, Seo, M.-D. | Deposit date: | 2015-11-19 | Release date: | 2016-11-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.698 Å) | Cite: | Crystal structure of SF216 from Shigella flexneri strain 5a To Be Published
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6JMR
| CD98hc extracellular domain bound to HBJ127 Fab and MEM-108 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, ... | Authors: | Lee, Y, Nishizawa, T, Kusakizako, T, Oda, K, Ishitani, R, Yokoyama, T, Nakane, T, Shirouzu, M, Nureki, O. | Deposit date: | 2019-03-13 | Release date: | 2019-06-19 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc. Nat.Struct.Mol.Biol., 26, 2019
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1RL1
| Solution structure of human Sgt1 CS domain | Descriptor: | Suppressor of G2 allele of SKP1 homolog | Authors: | Lee, Y.-T, Jacob, J, Michowski, W, Nowotny, M, Kuznicki, J, Chazin, W.J. | Deposit date: | 2003-11-24 | Release date: | 2004-05-04 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Human Sgt1 Binds HSP90 through the CHORD-Sgt1 Domain and Not the Tetratricopeptide Repeat Domain J.Biol.Chem., 279, 2004
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2JTT
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1TOA
| PERIPLASMIC ZINC BINDING PROTEIN TROA FROM TREPONEMA PALLIDUM | Descriptor: | GLYCEROL, PROTEIN (PERIPLASMIC BINDING PROTEIN TROA), ZINC ION | Authors: | Lee, Y.H, Deka, R.K, Norgard, M.V, Radolf, J.D, Hasemann, C.A. | Deposit date: | 1999-03-03 | Release date: | 1999-07-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Treponema pallidum TroA is a periplasmic zinc-binding protein with a helical backbone. Nat.Struct.Biol., 6, 1999
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5Y78
| Crystal structure of the triose-phosphate/phosphate translocator in complex with inorganic phosphate | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PHOSPHATE ION, Putative hexose phosphate translocator | Authors: | Lee, Y, Nishizawa, T, Takemoto, M, Kumazaki, K, Yamashita, K, Hirata, K, Minoda, A, Nagatoishi, S, Tsumoto, K, Ishitani, R, Nureki, O. | Deposit date: | 2017-08-16 | Release date: | 2017-10-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity Nat Plants, 3, 2017
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2DWO
| PFKFB3 in complex with ADP and PEP | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Lee, Y.H. | Deposit date: | 2006-08-16 | Release date: | 2007-07-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | A Direct Substrate-Substrate Interaction Found in the Kinase Domain of the Bifunctional Enzyme, 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase J.Mol.Biol., 370, 2007
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5Y79
| Crystal structure of the triose-phosphate/phosphate translocator in complex with 3-phosphoglycerate | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-PHOSPHOGLYCERIC ACID, CITRATE ANION, ... | Authors: | Lee, Y, Nishizawa, T, Takemoto, M, Kumazaki, K, Yamashita, K, Hirata, K, Minoda, A, Nagatoishi, S, Tsumoto, K, Ishitani, R, Nureki, O. | Deposit date: | 2017-08-16 | Release date: | 2017-10-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity Nat Plants, 3, 2017
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