2DWO

PFKFB3 in complex with ADP and PEP

Summary for 2DWO

Entry DOI	10.2210/pdb2dwo/pdb
Related	2AXN 2DWP 2I1V
Descriptor	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, 6-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywords	bifunctional enzyme, transferase, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	60549.52
Authors	Lee, Y.H. (deposition date: 2006-08-16, release date: 2007-07-03, Last modification date: 2023-10-25)
Primary citation	Kim, S.G.,Cavalier, M.,El-Maghrabi, M.R.,Lee, Y.H. A Direct Substrate-Substrate Interaction Found in the Kinase Domain of the Bifunctional Enzyme, 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase J.Mol.Biol., 370:14-26, 2007 Cited by PubMed: 17499765 DOI: 10.1016/j.jmb.2007.03.038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation