4OCZ
 
 | | Crystal structure of human soluble epoxide hydrolase complexed with 1-(1-isobutyrylpiperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea | | 分子名称: | 1-[1-(2-methylpropanoyl)piperidin-4-yl]-3-[4-(trifluoromethyl)phenyl]urea, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... | | 著者 | Lee, K.S.S, Liu, J, Wagner, K.M, Pakhomova, S, Dong, H, Morriseau, C, Fu, S.H, Yang, J, Wang, P, Ulu, A, Mate, C, Nguyen, L, Wullf, H, Eldin, M.L, Mara, A.A, Newcomer, M.E, Zeldin, D.C, Hammock, B.D. | | 登録日 | 2014-01-09 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy.
J.Med.Chem., 57, 2014
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4OD0
 | | Crystal structure of human soluble epoxide hydrolase complexed with 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea | | 分子名称: | 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... | | 著者 | Lee, K.S.S, Liu, J, Wagner, K.M, Pakhomova, S, Dong, H, Morisseau, C, Fu, S.H, Yang, J, Wang, P, Ulu, A, Mate, C, Nguyen, L, Wullf, H, Eldin, M.L, Mara, A.A, Newcomer, M.E, Zeldin, D.C, Hammock, B.D. | | 登録日 | 2014-01-09 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy.
J.Med.Chem., 57, 2014
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3HAF
 | | Human prion protein variant V129 domain swapped dimer | | 分子名称: | CADMIUM ION, CHLORIDE ION, Major prion protein | | 著者 | Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C. | | 登録日 | 2009-05-01 | | 公開日 | 2010-01-12 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
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3HAK
 | | Human prion protein variant V129 | | 分子名称: | Major prion protein | | 著者 | Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C. | | 登録日 | 2009-05-01 | | 公開日 | 2010-01-12 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
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3HEQ
 | | Human prion protein variant D178N with M129 | | 分子名称: | CADMIUM ION, Major prion protein | | 著者 | Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C. | | 登録日 | 2009-05-10 | | 公開日 | 2010-01-12 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
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3HES
 | | Human prion protein variant F198S with M129 | | 分子名称: | CADMIUM ION, Major prion protein | | 著者 | Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C. | | 登録日 | 2009-05-10 | | 公開日 | 2010-01-12 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
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3HER
 | | Human prion protein variant F198S with V129 | | 分子名称: | CADMIUM ION, Major prion protein | | 著者 | Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C. | | 登録日 | 2009-05-10 | | 公開日 | 2010-01-12 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
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3HJX
 | | Human prion protein variant D178N with V129 | | 分子名称: | CADMIUM ION, CHLORIDE ION, Major prion protein | | 著者 | Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C. | | 登録日 | 2009-05-22 | | 公開日 | 2010-01-12 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
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3HJ5
 | | Human prion protein variant V129 domain swapped dimer | | 分子名称: | Major prion protein | | 著者 | Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C. | | 登録日 | 2009-05-20 | | 公開日 | 2010-01-12 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
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3HR8
 | | Crystal Structure of Thermotoga maritima RecA | | 分子名称: | Protein recA | | 著者 | Lee, S, Kim, T.G, Jeong, E.-Y, Ban, C, Jeon, W.-J, Min, K.I, Song, K.-M, Heo, S.-D, Ku, J.K. | | 登録日 | 2009-06-09 | | 公開日 | 2010-06-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal Structure of RecA Protein from Thermotoga maritima MSB8
to be published
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8DEH
 | | Ankyrin domain of SKD3 | | 分子名称: | Caseinolytic peptidase B protein homolog | | 著者 | Lee, S, Tsai, F.T.F. | | 登録日 | 2022-06-20 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.815 Å) | | 主引用文献 | Structural basis of impaired disaggregase function in the oxidation-sensitive SKD3 mutant causing 3-methylglutaconic aciduria.
Nat Commun, 14, 2023
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8FDS
 | | Ankyrin domain of SKD3 isoform 2 | | 分子名称: | Caseinolytic peptidase B protein homolog, FORMIC ACID | | 著者 | Lee, S, Tsai, F.T.F, Chang, C. | | 登録日 | 2022-12-04 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural basis of impaired disaggregase function in the oxidation-sensitive SKD3 mutant causing 3-methylglutaconic aciduria.
Nat Commun, 14, 2023
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6NZ5
 | | YcjX-GDPCP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, YcjX Stress Protein | | 著者 | Lee, S, Tsai, J, Tsai, F.T, Sung, N, Lee, J, Chang, C. | | 登録日 | 2019-02-12 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.233 Å) | | 主引用文献 | Crystal Structure of the YcjX Stress Protein Reveals a Ras-Like GTP-Binding Protein.
J.Mol.Biol., 431, 2019
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8JZI
 | | Mutant S-adenosylmethionine synthase from C. glutamicum | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... | | 著者 | Lee, S, Kim, K.J. | | 登録日 | 2023-07-05 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Structural and Biochemical Studies on Product Inhibition of S-Adenosylmethionine Synthetase from Corynebacterium glutamicum .
J.Agric.Food Chem., 71, 2023
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8JZH
 | | C. glutamicum S-adenosylmethionine synthase | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, S-adenosylmethionine synthase, ... | | 著者 | Lee, S, Kim, K.J. | | 登録日 | 2023-07-05 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural and Biochemical Studies on Product Inhibition of S-Adenosylmethionine Synthetase from Corynebacterium glutamicum .
J.Agric.Food Chem., 71, 2023
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8JZG
 | | C. glutamicum S-adenosylmethionine synthase co-crystallized with Adenosine, triphosphate, and SAM | | 分子名称: | ADENOSINE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Lee, S, Kim, K.J. | | 登録日 | 2023-07-05 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Structural and Biochemical Studies on Product Inhibition of S-Adenosylmethionine Synthetase from Corynebacterium glutamicum .
J.Agric.Food Chem., 71, 2023
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7YMO
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1WYK
 | | SINDBIS VIRUS CAPSID PROTEIN (114-264) | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, FORMYL GROUP, SINDBIS VIRUS CAPSID PROTEIN | | 著者 | Lee, S, Kuhn, R.J, Rossmann, M.G. | | 登録日 | 1998-01-12 | | 公開日 | 1998-04-29 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Probing the potential glycoprotein binding site of sindbis virus capsid protein with dioxane and model building.
Proteins, 33, 1998
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6N8V
 | | Hsp104DWB open conformation | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 104 | | 著者 | Lee, S, Rho, S.H, Lee, J, Sung, N, Liu, J, Tsai, F.T.F. | | 登録日 | 2018-11-30 | | 公開日 | 2019-01-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (9.3 Å) | | 主引用文献 | Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation.
Cell Rep, 26, 2019
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6N8Z
 | | HSP104DWB extended conformation | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 104 | | 著者 | Lee, S, Rho, S.H, Lee, J, Sung, N, Liu, J, Tsai, F.T.F. | | 登録日 | 2018-11-30 | | 公開日 | 2019-01-02 | | 最終更新日 | 2019-01-16 | | 実験手法 | ELECTRON MICROSCOPY (9.3 Å) | | 主引用文献 | Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation.
Cell Rep, 26, 2019
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6N8T
 | | Hsp104DWB closed conformation | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 104 | | 著者 | Lee, S, Rho, S.H, Lee, J, Sung, N, Liu, J, Tsai, F.T.F. | | 登録日 | 2018-11-30 | | 公開日 | 2019-01-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | | 主引用文献 | Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation.
Cell Rep, 26, 2019
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5ZCH
 | | Crystal structure of OsPP2C50 I267W:OsPYL/RCAR3 with (+)-ABA | | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Abscisic acid receptor PYL3, MAGNESIUM ION, ... | | 著者 | Lee, S, Han, S. | | 登録日 | 2018-02-17 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.474 Å) | | 主引用文献 | Comprehensive survey of the VxG Phi L motif of PP2Cs from Oryza sativa reveals the critical role of the fourth position in regulation of ABA responsiveness.
Plant Mol.Biol., 101, 2019
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5ZCG
 | | Crystal structure of OsPP2C50 S265L/I267V:OsPYL/RCAR3 with (+)-ABA | | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ABA receptor RCAR3, MAGNESIUM ION, ... | | 著者 | Lee, S, Han, S. | | 登録日 | 2018-02-17 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Comprehensive survey of the VxG Phi L motif of PP2Cs from Oryza sativa reveals the critical role of the fourth position in regulation of ABA responsiveness.
Plant Mol.Biol., 101, 2019
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5ZCL
 | | Crystal structure of OsPP2C50 I267L:OsPYL/RCAR3 with (+)-ABA | | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ABA receptor RCAR3, MAGNESIUM ION, ... | | 著者 | Lee, S, Han, S. | | 登録日 | 2018-02-19 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.661 Å) | | 主引用文献 | Comprehensive survey of the VxG Phi L motif of PP2Cs from Oryza sativa reveals the critical role of the fourth position in regulation of ABA responsiveness.
Plant Mol.Biol., 101, 2019
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6NZ4
 | | YcjX-GDP (type I) | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, YcjX Stress Protein | | 著者 | Lee, S, Tsai, J, Tsai, F.T. | | 登録日 | 2019-02-12 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Crystal Structure of the YcjX Stress Protein Reveals a Ras-Like GTP-Binding Protein.
J.Mol.Biol., 431, 2019
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