4MFA
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![BU of 4mfa by Molmil](/molmil-images/mine/4mfa) | Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template O6MG and incoming TTP | 分子名称: | DNA polymerase beta, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-08-27 | 公開日 | 2014-08-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Structures of human DNA polymerase beta inserting bases opposite templating O6MG To be Published
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4M2Y
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![BU of 4m2y by Molmil](/molmil-images/mine/4m2y) | Structure of human DNA polymerase beta complexed with 8-BrG as the template base in a 1-nucleotide gapped DNA | 分子名称: | DNA polymerase beta, SODIUM ION, down-primer, ... | 著者 | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-08-05 | 公開日 | 2014-01-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
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6JCM
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![BU of 6jcm by Molmil](/molmil-images/mine/6jcm) | Crystal structure of ligand-free Rv0187. | 分子名称: | ACETATE ION, Probable O-methyltransferase | 著者 | Kim, J, Lee, S. | 登録日 | 2019-01-29 | 公開日 | 2019-12-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structural and biochemical characterization of Rv0187, an O-methyltransferase from Mycobacterium tuberculosis. Sci Rep, 9, 2019
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4M47
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![BU of 4m47 by Molmil](/molmil-images/mine/4m47) | structure of human DNA polymerase complexed with 8-BrG in the template base paired with incoming non-hydrolyzable GTP | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA polymerase beta, MAGNESIUM ION, ... | 著者 | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-08-06 | 公開日 | 2014-01-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
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6JCL
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![BU of 6jcl by Molmil](/molmil-images/mine/6jcl) | Crystal structure of cofactor-bound Rv0187 from MTB | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Probable O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Kim, J, Lee, S. | 登録日 | 2019-01-29 | 公開日 | 2019-12-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.644 Å) | 主引用文献 | Structural and biochemical characterization of Rv0187, an O-methyltransferase from Mycobacterium tuberculosis. Sci Rep, 9, 2019
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7LCD
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![BU of 7lcd by Molmil](/molmil-images/mine/7lcd) | |
4MF8
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![BU of 4mf8 by Molmil](/molmil-images/mine/4mf8) | Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template O6MG and incoming CTP | 分子名称: | DNA polymerase beta, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-08-27 | 公開日 | 2014-08-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Structures of human DNA polymerase beta inserting bases opposite templating O6MG To be Published
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4MFF
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![BU of 4mff by Molmil](/molmil-images/mine/4mff) | Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable TTP | 分子名称: | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA polymerase beta, MAGNESIUM ION, ... | 著者 | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-08-27 | 公開日 | 2014-04-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
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4MFC
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![BU of 4mfc by Molmil](/molmil-images/mine/4mfc) | Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable CTP | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA polymerase beta, MAGNESIUM ION, ... | 著者 | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-08-27 | 公開日 | 2014-04-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
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4NM1
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![BU of 4nm1 by Molmil](/molmil-images/mine/4nm1) | Structure of human DNA polymerase beta complexed with a nicked DNA containing a 8BrG-C at N-1 position and G-C at N position | 分子名称: | 5'-D(*CP*CP*GP*AP*CP*GP*(BGM)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | 著者 | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-11-14 | 公開日 | 2014-01-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.415 Å) | 主引用文献 | Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
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4NM2
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![BU of 4nm2 by Molmil](/molmil-images/mine/4nm2) | Structure of human DNA polymerase beta complexed with a nicked DNA containing a 8BrG-G at N-1 position and G-C at N position | 分子名称: | 5'-D(*CP*CP*GP*AP*CP*GP*(BGM)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | 著者 | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-11-14 | 公開日 | 2014-01-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.524 Å) | 主引用文献 | Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
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4NLK
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![BU of 4nlk by Molmil](/molmil-images/mine/4nlk) | Structure of human DNA polymerase beta complexed with 8BrG in the template base-paired with incoming non-hydrolyzable CTP | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', ... | 著者 | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-11-14 | 公開日 | 2014-01-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.494 Å) | 主引用文献 | Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
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4NLN
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![BU of 4nln by Molmil](/molmil-images/mine/4nln) | Structure of human DNA polymerase beta complexed with nicked DNA containing a template 8BrG and incoming CTP | 分子名称: | 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | 著者 | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-11-14 | 公開日 | 2014-01-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.261 Å) | 主引用文献 | Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
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4NLZ
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![BU of 4nlz by Molmil](/molmil-images/mine/4nlz) | Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template 8BrG and incoming GTP | 分子名称: | 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*AP*G)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | 著者 | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-11-14 | 公開日 | 2014-01-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.683 Å) | 主引用文献 | Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
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4NXZ
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![BU of 4nxz by Molmil](/molmil-images/mine/4nxz) | DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable TTP with manganese in the active site | 分子名称: | 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | 著者 | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-12-09 | 公開日 | 2014-04-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.557 Å) | 主引用文献 | Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
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4NY8
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![BU of 4ny8 by Molmil](/molmil-images/mine/4ny8) | DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable CTP with manganese in the active site | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', ... | 著者 | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-12-10 | 公開日 | 2014-04-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.246 Å) | 主引用文献 | Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
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4O5C
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![BU of 4o5c by Molmil](/molmil-images/mine/4o5c) | |
4O5E
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![BU of 4o5e by Molmil](/molmil-images/mine/4o5e) | |
4O5K
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![BU of 4o5k by Molmil](/molmil-images/mine/4o5k) | |
6LHU
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![BU of 6lhu by Molmil](/molmil-images/mine/6lhu) | High resolution structure of FANCA C-terminal domain (CTD) | 分子名称: | Fanconi anemia complementation group A | 著者 | Jeong, E, Lee, S, Shin, J, Kim, Y, Kim, J, Scharer, O, Kim, Y, Kim, H, Cho, Y. | 登録日 | 2019-12-10 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex. Nucleic Acids Res., 48, 2020
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6LHW
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![BU of 6lhw by Molmil](/molmil-images/mine/6lhw) | Structure of N-terminal and C-terminal domains of FANCA | 分子名称: | Fanconi anemia complementation group A | 著者 | Jeong, E, Lee, S, Shin, J, Kim, Y, Kim, J, Scharer, O, Kim, Y, Kim, H, Cho, Y. | 登録日 | 2019-12-10 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.84 Å) | 主引用文献 | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex. Nucleic Acids Res., 48, 2020
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6LHV
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![BU of 6lhv by Molmil](/molmil-images/mine/6lhv) | Structure of FANCA and FANCG Complex | 分子名称: | Fanconi anemia complementation group A, Fanconi anemia complementation group G | 著者 | Jeong, E, Lee, S, Shin, J, Kim, Y, Scharer, O, Kim, Y, Kim, H, Cho, Y. | 登録日 | 2019-12-10 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.59 Å) | 主引用文献 | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex. Nucleic Acids Res., 48, 2020
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2AG2
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![BU of 2ag2 by Molmil](/molmil-images/mine/2ag2) | Crystal Structure Analysis of GM2-activator protein complexed with Phosphatidylcholine | 分子名称: | (7R)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM 4-OXIDE, 2-(((R)-2,3-DIHYDROXYPROPYL)PHOSPHORYLOXY)-N,N,N-TRIMETHYLETHANAMINIUM, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F. | 登録日 | 2005-07-26 | 公開日 | 2005-10-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity. Biochemistry, 44, 2005
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2AG9
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![BU of 2ag9 by Molmil](/molmil-images/mine/2ag9) | Crystal Structure of the Y137S mutant of GM2-Activator Protein | 分子名称: | Ganglioside GM2 activator, ISOPROPYL ALCOHOL, MYRISTIC ACID | 著者 | Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F. | 登録日 | 2005-07-26 | 公開日 | 2005-10-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity. Biochemistry, 44, 2005
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2AGC
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![BU of 2agc by Molmil](/molmil-images/mine/2agc) | Crystal Structure of mouse GM2- activator Protein | 分子名称: | Ganglioside GM2 activator, LAURIC ACID, MYRISTIC ACID | 著者 | Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F. | 登録日 | 2005-07-26 | 公開日 | 2005-10-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity. Biochemistry, 44, 2005
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