7WVJ
 
 | | NT-mut(K117D,K139D,K145D) TLR3 -poly I:C complex | | 分子名称: | RNA (46-MER), Toll-like receptor 3 | | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | 登録日 | 2022-02-10 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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7WV5
 | | ectoTLR3-poly(I:C) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (46-MER), ... | | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | 登録日 | 2022-02-09 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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7WV4
 | | ectoTLR3-poly(I:C) cluster | | 分子名称: | RNA (80-MER), Toll-like receptor 3 | | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | 登録日 | 2022-02-09 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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7WVE
 | | CT-mut (D523K,D524K,E527K) TLR3-poly(I:C) complex | | 分子名称: | RNA (46-MER), Toll-like receptor 3 | | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | 登録日 | 2022-02-10 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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7WV3
 | | Toll-like receptor3 linear cluster | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (80-MER), ... | | 著者 | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | 登録日 | 2022-02-09 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | | 主引用文献 | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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5X3F
 | | Crystal structure of the YgjG-Protein A-Zpa963-PKA catalytic domain | | 分子名称: | Putrescine aminotransferase,Immunoglobulin G-binding protein A, Zpa963,cAMP-dependent protein kinase catalytic subunit alpha | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2017-02-05 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5XBY
 | | Crystal structure of the PKA-Protein A fusion protein (end-to-end fusion) | | 分子名称: | cAMP-dependent protein kinase type II-alpha regulatory subunit,Immunoglobulin G-binding protein A | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2017-03-21 | | 公開日 | 2017-07-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H76
 | | Crystal structure of the DARPin-Protein A fusion protein | | 分子名称: | DARPin,Immunoglobulin G-binding protein A | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H77
 | | Crystal structure of the PKA-protein A fusion protein | | 分子名称: | cAMP-dependent protein kinase type II-alpha regulatory subunit,Immunoglobulin G-binding protein A | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.197 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H78
 | | Crystal structure of the PKA-DHR14 fusion protein | | 分子名称: | cAMP-dependent protein kinase type II-alpha regulatory subunit,DHR14 | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H7C
 | | Crystal structure of a repeat protein with two Protein A-DHR14 repeat modules | | 分子名称: | Immunoglobulin G-binding protein A, DHR14 | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H7D
 | | Crystal structure of the YgjG-protein A-Zpa963-calmodulin complex | | 分子名称: | CALCIUM ION, Putrescine aminotransferase,Immunoglobulin G-binding protein A, Zpa963,Calmodulin | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H75
 | | Crystal structure of the MrsD-Protein A fusion protein | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Mersacidin decarboxylase,Immunoglobulin G-binding protein A | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.738 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H79
 | | Crystal structure of a repeat protein with three Protein A repeat module | | 分子名称: | Immunoglobulin G-binding protein A | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H7B
 | | Crystal structure of a repeat protein with five Protein A repeat modules | | 分子名称: | Immunoglobulin G-binding protein A | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H7A
 | | Crystal structure of a repeat protein with four Protein A repeat module | | 分子名称: | Immunoglobulin G-binding protein A | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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2OLE
 | | Crystal Structure Of Human Dipeptidyl Peptidase IV (DPPIV) Complex With Cyclic Hydrazine Derivatives | | 分子名称: | (2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE, Dipeptidyl peptidase 4 | | 著者 | Kim, S.S, Ahn, J.H, Lee, J.O. | | 登録日 | 2007-01-19 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Synthesis, biological evaluation and structural determination of beta-aminoacyl-containing cyclic hydrazine derivatives as dipeptidyl peptidase IV (DPP-IV) inhibitors
Bioorg.Med.Chem.Lett., 17, 2007
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5GRX
 | | Crystal structure of disulfide-bonded diabody | | 分子名称: | diabody protein | | 著者 | Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. | | 登録日 | 2016-08-12 | | 公開日 | 2016-10-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | | 主引用文献 | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface.
Sci Rep, 6, 2016
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1BI7
 | | MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURE OF THE CDK6-P16INK4A TUMOR SUPPRESSOR COMPLEX | | 分子名称: | CYCLIN-DEPENDENT KINASE 6, MULTIPLE TUMOR SUPPRESSOR | | 著者 | Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P. | | 登録日 | 1998-06-22 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
Nature, 395, 1998
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1BI8
 | | MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEX | | 分子名称: | CYCLIN-DEPENDENT KINASE 6, CYCLIN-DEPENDENT KINASE INHIBITOR | | 著者 | Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P. | | 登録日 | 1998-06-22 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
Nature, 395, 1998
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5EWX
 | | Fusion protein of T4 lysozyme and B4 domain of protein A from staphylococcal aureus with chemical cross-linker EY-CBS | | 分子名称: | 2,2'-ethyne-1,2-diylbis{5-[(chloroacetyl)amino]benzenesulfonic acid}, Endolysin,Immunoglobulin G-binding protein A,Endolysin | | 著者 | Jeong, W.H, Lee, H, Song, D.H, Lee, J.O. | | 登録日 | 2015-11-22 | | 公開日 | 2016-03-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker.
Nat Commun, 7, 2016
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4XTT
 | | Structural Studies of Potassium Transport Protein KtrA Regulator of Conductance of K+ (RCK) C domain in Complex with Cyclic Diadenosine Monophosphate (c-di-AMP) | | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Putative potassium transport protein | | 著者 | Kim, H, Youn, S.J, Kim, S.O, Ko, J, Lee, J.O, Choi, B.S. | | 登録日 | 2015-01-24 | | 公開日 | 2015-05-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.708 Å) | | 主引用文献 | Structural Studies of Potassium Transport Protein KtrA Regulator of Conductance of K+ (RCK) C Domain in Complex with Cyclic Diadenosine Monophosphate (c-di-AMP)
J.Biol.Chem., 290, 2015
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1X8D
 | | Crystal structure of E. coli YiiL protein containing L-rhamnose | | 分子名称: | Hypothetical protein yiiL, L-RHAMNOSE | | 著者 | Ryu, K.S, Kim, J.I, Cho, S.J, Park, D, Park, C, Lee, J.O, Choi, B.S. | | 登録日 | 2004-08-18 | | 公開日 | 2005-05-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Insights into the Monosaccharide Specificity of Escherichia coli Rhamnose Mutarotase
J.Mol.Biol., 349, 2005
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4M4D
 | | Crystal structure of lipopolysaccharide binding protein | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Lipopolysaccharide-binding protein | | 著者 | Eckert, J.K, Kim, Y.J, Kim, J.I, Gurtler, K, Oh, D.Y, Ploeg, A.H, Pickkers, P, Lundvall, L, Hamann, L, Giamarellos-Bourboulis, E, Kubarenko, A.V, Weber, A.N, Kabesch, M, Kumpf, O, An, H.J, Lee, J.O, Schumann, R.R. | | 登録日 | 2013-08-07 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.909 Å) | | 主引用文献 | The crystal structure of lipopolysaccharide binding protein reveals the location of a frequent mutation that impairs innate immunity.
Immunity, 39, 2013
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5GRZ
 | | Crystal structure of disulfide-bonded diabody | | 分子名称: | diabody | | 著者 | Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. | | 登録日 | 2016-08-13 | | 公開日 | 2016-10-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface.
Sci Rep, 6, 2016
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