1IJX
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![BU of 1ijx by Molmil](/molmil-images/mine/1ijx) | CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF SECRETED FRIZZLED-RELATED PROTEIN 3 (SFRP-3;FZB) | 分子名称: | SECRETED FRIZZLED-RELATED SEQUENCE PROTEIN 3, SULFATE ION | 著者 | Dann III, C.E, Hsieh, J.C, Rattner, A, Sharma, D, Nathans, J, Leahy, D.J. | 登録日 | 2001-04-30 | 公開日 | 2001-07-11 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains. Nature, 412, 2001
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2P8V
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![BU of 2p8v by Molmil](/molmil-images/mine/2p8v) | Crystal structure of human Homer3 EVH1 domain | 分子名称: | Homer protein homolog 3, SULFATE ION | 著者 | Bouyain, S, Tu, J, Huang, G.N, Worley, P.F, Leahy, D. | 登録日 | 2007-03-23 | 公開日 | 2007-11-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins. Science, 319, 2008
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3U7U
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![BU of 3u7u by Molmil](/molmil-images/mine/3u7u) | Crystal structure of extracellular region of human epidermal growth factor receptor 4 in complex with neuregulin-1 beta | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuregulin 1, Receptor tyrosine-protein kinase erbB-4 | 著者 | Liu, P, Cleveland IV, T.E, Bouyain, S, Longo, P.A, Leahy, D.J. | 登録日 | 2011-10-14 | 公開日 | 2012-08-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | A single ligand is sufficient to activate EGFR dimers. Proc.Natl.Acad.Sci.USA, 109, 2012
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3U2P
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![BU of 3u2p by Molmil](/molmil-images/mine/3u2p) | Crystal structure of N-terminal three extracellular domains of ErbB4/Her4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-4 | 著者 | Liu, P, Bouyain, S, Elgenbrot, C, Leahy, D.J. | 登録日 | 2011-10-04 | 公開日 | 2011-11-09 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | The ErbB4 extracellular region retains a tethered-like conformation in the absence of the tether. Protein Sci., 21, 2012
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2IBG
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![BU of 2ibg by Molmil](/molmil-images/mine/2ibg) | |
3U9U
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![BU of 3u9u by Molmil](/molmil-images/mine/3u9u) | Crystal Structure of Extracellular Domain of Human ErbB4/Her4 in complex with the Fab fragment of mAb1479 | 分子名称: | Fab Heavy Chain, Fab Light Chain, Receptor tyrosine-protein kinase erbB-4 | 著者 | Hollmen, M, Liu, P, Wildiers, H, Reinvall, I, Vandorpe, T, Smeets, A, Deraedt, K, Vahlberg, T, Joensuu, H, Leahy, D.J, Schoffski, P, Elenius, K. | 登録日 | 2011-10-19 | 公開日 | 2012-10-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | 主引用文献 | Proteolytic processing of ErbB4 in breast cancer. Plos One, 7, 2012
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1N8Y
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![BU of 1n8y by Molmil](/molmil-images/mine/1n8y) | Crystal structure of the extracellular region of rat HER2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, protooncoprotein | 著者 | Cho, H.-S, Mason, K, Ramyar, K.X, Stanley, A.M, Gabelli, S.B, Denney Jr, D.W, Leahy, D.J. | 登録日 | 2002-11-21 | 公開日 | 2003-02-18 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the Extracellular Region of HER2 Alone and in complex with the Herceptin Fab Nature, 421, 2003
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2IBB
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![BU of 2ibb by Molmil](/molmil-images/mine/2ibb) | |
3TNU
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![BU of 3tnu by Molmil](/molmil-images/mine/3tnu) | Heterocomplex of coil 2B domains of human intermediate filament proteins, keratin 5 (KRT5) and keratin 14 (KRT14) | 分子名称: | Keratin, type I cytoskeletal 14, type II cytoskeletal 5 | 著者 | Lee, C.H, Kim, M.S, Leahy, D.J, Coulombe, P.A. | 登録日 | 2011-09-02 | 公開日 | 2012-06-20 | 最終更新日 | 2012-08-01 | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | 主引用文献 | Structural basis for heteromeric assembly and perinuclear organization of keratin filaments. Nat.Struct.Mol.Biol., 19, 2012
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1N8Z
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![BU of 1n8z by Molmil](/molmil-images/mine/1n8z) | Crystal structure of extracellular domain of human HER2 complexed with Herceptin Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Herceptin Fab (antibody) - heavy chain, Herceptin Fab (antibody) - light chain, ... | 著者 | Cho, H.-S, Mason, K, Ramyar, K.X, Stanley, A.M, Gabelli, S.B, Denney Jr, D.W, Leahy, D.J. | 登録日 | 2002-11-21 | 公開日 | 2003-02-18 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Structure of the Extracellular Region of HER2 Alone and in Complex with the Herceptin Fab Nature, 421, 2003
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1DDV
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![BU of 1ddv by Molmil](/molmil-images/mine/1ddv) | CRYSTAL STRUCTURE OF THE HOMER EVH1 DOMAIN WITH BOUND MGLUR PEPTIDE | 分子名称: | GLGF-DOMAIN PROTEIN HOMER, METABOTROPIC GLUTAMATE RECEPTOR MGLUR5 | 著者 | Beneken, J, Tu, J.C, Xiao, B, Worley, P.F, Leahy, D.J. | 登録日 | 1999-11-11 | 公開日 | 2000-05-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition. Neuron, 26, 2000
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1AT0
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![BU of 1at0 by Molmil](/molmil-images/mine/1at0) | 17-kDA fragment of hedgehog C-terminal autoprocessing domain | 分子名称: | 17-HEDGEHOG | 著者 | Hall, T.M.T, Porter, J.A, Young, K.E, Koonin, E.V, Beachy, P.A, Leahy, D.J. | 登録日 | 1997-08-15 | 公開日 | 1997-11-12 | 最終更新日 | 2017-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins. Cell(Cambridge,Mass.), 91, 1997
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3N1F
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![BU of 3n1f by Molmil](/molmil-images/mine/3n1f) | Crystal Structure of IhhN bound to CDOFn3 | 分子名称: | CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Indian hedgehog protein, ... | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-15 | 公開日 | 2010-06-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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3BXK
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![BU of 3bxk by Molmil](/molmil-images/mine/3bxk) | Crystal structure of the P/Q-type calcium channel (CaV2.1) IQ domain and CA2+calmodulin complex | 分子名称: | CALCIUM ION, Calmodulin, SULFATE ION, ... | 著者 | Mori, M.X, Vander Kooi, C.W, Leahy, D.J, Yue, D.T. | 登録日 | 2008-01-14 | 公開日 | 2008-03-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal structure of the P/Q-type calcium channel (CaV2.1) IQ domain and CA2+calmodulin complex To be Published
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3BXL
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![BU of 3bxl by Molmil](/molmil-images/mine/3bxl) | Crystal structure of the R-type calcium channeL (CaV2.3) IQ domain and CA2+calmodulin complex | 分子名称: | CALCIUM ION, Calmodulin, SULFATE ION, ... | 著者 | Mori, M.X, Vander Kooi, C.W, Leahy, D.J, Yue, D.T. | 登録日 | 2008-01-14 | 公開日 | 2008-03-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the CaV2 IQ domain in complex with Ca2+/calmodulin To be Published
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3N1Q
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![BU of 3n1q by Molmil](/molmil-images/mine/3n1q) | Crystal Structure of DhhN bound to CDOFn3 | 分子名称: | CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Desert hedgehog protein, ... | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-16 | 公開日 | 2010-06-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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3N1M
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![BU of 3n1m by Molmil](/molmil-images/mine/3n1m) | Crystal Structure of IhhN bound to BOCFn3 | 分子名称: | Brother of CDO, CALCIUM ION, Indian hedgehog protein, ... | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-15 | 公開日 | 2010-06-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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3N1O
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![BU of 3n1o by Molmil](/molmil-images/mine/3n1o) | Crystal structure of IhhN | 分子名称: | CALCIUM ION, Indian hedgehog protein, ZINC ION | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-16 | 公開日 | 2010-06-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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3N1G
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![BU of 3n1g by Molmil](/molmil-images/mine/3n1g) | Crystal structure of DhhN bound to BOCFn3 | 分子名称: | Brother of CDO, CALCIUM ION, Desert hedgehog protein, ... | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-15 | 公開日 | 2010-06-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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3N1P
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![BU of 3n1p by Molmil](/molmil-images/mine/3n1p) | Crystal Structure of IhhN bound to BOCFn3 | 分子名称: | Brother of CDO, CALCIUM ION, Indian hedgehog protein, ... | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-16 | 公開日 | 2010-06-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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3N1R
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![BU of 3n1r by Molmil](/molmil-images/mine/3n1r) | |
1DDW
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![BU of 1ddw by Molmil](/molmil-images/mine/1ddw) | HOMER EVH1 DOMAIN UNLIGANDED | 分子名称: | GLGF-DOMAIN PROTEIN HOMER | 著者 | Beneken, J, Tu, J.C, Xiao, B, Worley, P.F, Leahy, D.J. | 登録日 | 1999-11-11 | 公開日 | 2000-05-10 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition. Neuron, 26, 2000
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3D1M
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1YN4
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![BU of 1yn4 by Molmil](/molmil-images/mine/1yn4) | Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens | 分子名称: | EapH1, ZINC ION | 著者 | Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J. | 登録日 | 2005-01-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens. J.Biol.Chem., 280, 2005
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1YN5
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![BU of 1yn5 by Molmil](/molmil-images/mine/1yn5) | Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens | 分子名称: | EapH2 | 著者 | Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J. | 登録日 | 2005-01-23 | 公開日 | 2005-03-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens. J.Biol.Chem., 280, 2005
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